Physiology (Research unit)
Id: VUB_438
Vrije Universiteit Brussel
The focus of the Department of Physiology - Immunology is directed towards the application of basic immunological knowledge and molecular biotechnology for the understanding, diagnosis and treatment of human diseases, in particular haematological malignancies and solid tumors. Molecular techniques and tools developed in a research setting are made available for the diagnosis and the follow-up of patients. Studies in pre- clinical animal models are performed with the aim to develop strategies for immune intervention in human malignancies. Several phase I-II clinical trials of 'active specific immunotherapy' of cancer patients (i.e. cancer vaccine trials) have been initiated and are co-ordinated by the Laboratory of Physiology-Immunology. The Laboratory participates actively in a collaborative project of 'Cell Therapy', using genetically modified dendritic cells as therapeutic cancer vaccine. Since a major part of the laboratory activities and efforts are oriented towards the application into the clinic, the research can be best described as 'translational R & D'.
- Post addresses:
Laarbeeklaan 103, 1090 Jette, BE
- Electronic addresses:
- +32-2-4774568
- Electronic addresses:
- +32-2-4774569
- Electronic addresses:
- http://www.vub.ac.be/infovoor/onderzoekers/research/team.php?team_code=FYSP
- Acronym:
- FYSP
- Keywords:
- Bispecific Antibodies,Dendritic Cells,Evoked Potentials,Immunology,Immunotherapy,Oncology,Tonic Pain
- Discipline codes:
- BIOMEDICAL SCIENCES (B)
- Biophysics
- Cytology, oncology, cancerology
- Medicine (human and vertebrates)
- Physiology
- Haematology, extracellular fluids
- Biophysics
- BIOMEDICAL SCIENCES (B)
Research projects
Dissecting dendritic cell biology and the signals that control lymphocyte activation.
Co-ordinator 1 Oct 2005 → 30 Sep 2011
HEPADIP : Hepatic and adipose tissue and functions in the Metabolic Syndrome.
Co-ordinator 1 Nov 2005 → 31 Oct 2010
Liver and adipose Tissue: Functions in the Metabolic Syndrome
Co-ordinator 1 Jan 2007 → 31 Dec 2010
MTA - Material Transfer Agreement. Evaluation of soluble CD83 variants on human monocyte-derived dendritic cells and in allo-MLR.
Co-ordinator 6 Jun 2007 → 5 Jun 2012
Mechanisms responsible for dysfunction of cytotoxic T lymfocytes in patients infected with HIV-1.
Co-ordinator 1 Jan 2009 → 31 Dec 2010
Novel macrophage and myeloid dendritic cell markers for in vivo imaging and therapy of inflammatory diseases; inflammation trackin "inflammatrack".
Co-ordinator 1 Jan 2009 → 31 Dec 2012
Leader
KRISTIAAN THIELEMANS
Member 1 Oct 2006 → 30 Sep 2010
Leader 31 Dec 1999 → 31 Dec 2099
Members
Griet STEURS
Member (Recently ended) 1 Sep 2000 → 31 Dec 2009
Member 15 Feb 2010 → 14 Feb 2011Sofie MOORTHAMERS Recently ended
Member (Recently ended) 11 Jan 2010 → 26 Jan 2010
Member (Recently ended) 1 Feb 2010 → 23 Feb 2010Sonja VAN MEIRVENNE
Member (Recently ended) 11 Jan 2010 → 9 May 2010
Member (Historic) 1 Oct 1996 → 30 Sep 2000
Member 15 Feb 2008 → 31 Dec 9999
Member (Historic) 1 Oct 2007 → 31 Dec 2007
Member (Historic) 1 Nov 2000 → 31 Oct 2006
Member (Historic) 1 Nov 2000 → 30 Sep 2007
Member (Historic) 1 Nov 2000 → 31 Oct 2004
Member (Historic) 1 Nov 2000 → 31 Oct 2002
Member (Historic) 1 Nov 2000 → 7 Oct 2006
Member (Historic) 1 Nov 2000 → 7 Jan 2005
Member (Historic) 1 Nov 2000 → 8 Feb 2006
Member (Historic) 1 Nov 2000 → 5 Jan 2005Inge BETZ
Member (Recently ended) 1 Jul 2009 → 31 Dec 2009
Member 1 Jan 2010 → 31 Dec 2010
Member (Recently ended) 1 Jan 2010 → 12 Feb 2010
Member (Recently ended) 18 Dec 2008 → 30 Jun 2009
Member (Recently ended) 1 Jan 2009 → 30 Jun 2009
Member (Recently ended) 16 Aug 2007 → 31 Dec 2008
Member (Recently ended) 1 Oct 2007 → 31 Dec 2008Brenda DE KEERSMAECKER
Member 1 Jan 2010 → 31 Dec 2010
Member (Historic) 15 Feb 2007 → 31 Dec 2007
Member (Recently ended) 15 Feb 2007 → 31 Dec 2008
Member (Recently ended) 15 Feb 2007 → 31 Dec 2009
Member 15 Feb 2007 → 31 Dec 2010PETRA ROMAN
Member (Historic) 1 Jan 2006 → 4 Jan 2006
Member (Historic) 1 Oct 2007 → 31 Dec 2007
Member 1 Jan 2008 → 31 Dec 9999
Member (Historic) 1 Jan 2007 → 31 Dec 2007
Member (Historic) 1 May 1999 → 31 Dec 2001
Member (Historic) 1 May 1999 → 31 Dec 2002
Member (Historic) 1 Jan 2004 → 22 Jan 2004
Member (Historic) 1 Jan 2002 → 15 Dec 2004
Member (Historic) 1 Jan 2002 → 16 Nov 2005
Member (Historic) 1 Jan 2004 → 13 Jan 2004
Member (Historic) 1 Jan 2002 → 7 Oct 2006
Member (Recently ended) 1 Jan 2008 → 31 Dec 2009
Member (Recently ended) 1 Jan 2008 → 31 Dec 2008
Member (Historic) 1 Feb 2007 → 31 Dec 2007
Member (Historic) 1 Jan 2002 → 7 Jan 2005
Member (Historic) 1 Jan 2002 → 8 Feb 2006
Member (Historic) 1 Jan 2002 → 30 Sep 2006
Member (Historic) 1 Jan 2002 → 31 Dec 2003
Member (Historic) 1 Jan 2002 → 31 Dec 2005
Member (Historic) 1 Jan 2002 → 31 Dec 2007
Member (Historic) 1 Jan 2002 → 5 Jan 2005
Member 1 Jan 2008 → 30 Nov 2036
Member (Recently ended) 1 Jan 2009 → 31 Dec 2009
Member 1 Jan 2010 → 31 Dec 2010Kurt VANHOUTTE
Member 1 Jan 2010 → 31 Dec 2010
Member (Historic) 1 Jul 2007 → 30 Sep 2007
Member (Recently ended) 19 Sep 2008 → 30 Jun 2009
Member (Recently ended) 1 Feb 2008 → 30 Jun 2009Xavier DEBAERE Recently ended
Member (Recently ended) 23 Nov 2009 → 31 Dec 2009
Member (Recently ended) 1 Jan 2010 → 30 Jun 2010