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Project

Internationale Wetenschappelijke Samenwerking: Rijksuniversiteit Groningen - VUB. Thema: Penology - Criminology Titel project: Prisoners' return to society: (semi-) automatic versus discretionary release. A comparative study of early' release pathways...

Vrije Universiteit Brussel

With regard to early release, Belgium and the Netherlands have different legal systems, policies and practices, each with their own obstacles and opportunities. This research aims to contribute to the understanding of these practices by comparing the Dutch system of semi-automatic conditional release and the Belgian system of discretionary conditional release, to reveal the barriers and opportunities of these different release trajectories for prisoners who already served at least one prison ...

Project

Internationale workshop/School over tracer- en tijdsschaalmethoden voor complexe geofysische- en milieuprocessen.(Louvain-la-Neuve van 16/8/2011 tot 19/08/2011) Historic

Vrije Universiteit Brussel

Understanding advective-diffusive transport and production/destruction processes of trace constituents in natural fluid flows is an important challenge in Earth and environmental sciences with many diverse applications. Moreover, geophysical and environmental models routinely produce huge amounts of real numbers. To make sense of them, computer graphics is not sufficient, and has to be complemented with specific interpretation methods. Among them, an approach that is progressively becoming po...

Project

International Francqui Chair 2011-12 Recently ended

Ghent University

Professor Heikki Pihlajamäki (full professor of Legal history at the University of Helsinki) resided in the Ghent University Law School, between October 2012 and March 2013 as international Francqui Professor (2011-12). He delivered several guest lectures, organised a national and an international congress, guided young researchers and gave several master classes voor doctoral students in the area of comparative legal history.

Project

International Francqui Professor 2009-2010 for Prof. Ingrid Daubechies Historic

Vrije Universiteit Brussel

In recent years exciting new developments in mathematics and computer science have opened up new domains of application for computational mathematics. These developments bring new challenges, for which new approaches and tools must be developed. Machine learning and compressed sensing are two typical examples; they draw not only from traditional linear-algebra-based numerical analysis or approximation theory, but also from information theory, graph theory, the geometry of Banach spaces, proba...

Project

International Francqui Professor Leerstoel 2010-2011 : toegekend aan Prof. dr. Jostein Gripsrud. (University of Bergen, Norway) (Voorheen Interuniversitaire Buitenlandse Francqui Leerstoel genoemd) Recently ended

Vrije Universiteit Brussel

The general theme of the class of excellence, which includes an inaugural lecture and 4 seminars is "Democracy and the digitisation of audiovisual culture". Also the end symposium will deal with this theme. Inaugural Lecture: 'Media and the public sphere' - This lecture aims to generate attention for the class of excellence, but most importantly for evidence-based debates on the media and their importance for democratic societies. Seminar 1: 'Changing structures of the public sphere - The...

Project

International Francqui Professor Leerstoel 2013-2014 : toegekend aan Prof. dr. Frans Halzen. (University of Wisconsin, USA)

Vrije Universiteit Brussel

Annualy, the Francqui Foundation grants 3 International Francqui Professor Chairs to enable a foreign scientist to stay in Belgium for a periode from 3 to 6 months.

Project

International Francqui Professorship – Bruce Ernest Logan Recently ended

Ghent University

This scholarship finances Bruce Ernest Logan’s sabbatical in Belgium

Project

International interdisciplinary course: children's rights in a globalized world. Historic

University of Antwerp

iImplementation of the project "International interdisciplinary course: children's rights in a globalized world: from principles to practice". Expansion and deepening of globalisation results in the challenges of poverty, environmental degradation, child soldiering, child labour and migration assuming a new dimension. These developments challenge the concept of chldren's rights and ask for critical reflection on the role of children's rights as leverage for societal change.

Project

International judicial politics: EU and US responses to WTO litigation.

University of Antwerp

How do the European Union and the United States respond to legal challenges brought in WTO litigation? As the current Doha Round of multilateral trade negotiations at the World Trade Organization is deadlocked, answering this question is key to assess the strength and nature of the WTO judicial arm, and to assess whether and how the WTO can remain a key institution in global economic governance. We will investigate responses to WTO litigation of the European Union (EU) and the United States (...

Project

International mission on prognosis and analysis of clinical trials in traumatic brain injury. Historic

University of Antwerp

IMPACT: International Mission for Prognosis and Analysis of Clinical Trials in TBI. Traumatic Brain Injury (TBI) may afflict us all, but young adult males are particularly at risk. IMPACT is an international multidisciplinary effort to advance clinical research programmes in search of better treatment. Nearly 10 years of work has resulted in the development of a prognostic calculator for establishing prognosis in individual patients, proposals for standardization of data collection in TBI stu...

Project

International negotiations in the European Council: Preferences of Negotiators Identified. Historic

University of Antwerp

Negotiations in the EU are of prime importance for international and domestic politics. Explaining EU decision making requires good data regarding the preferences of negotiators. Collecting this data is an ambitious empirical undertaking. This project aims to develop a database of negotiators' preferences. This will create an important stimulus for research on international negotiations, of which several researchers will profit.

Project

International Network for Sensory Research.

University of Antwerp

Psychologists, philosophers and cognitive scientists have assumed until very recently that we can study the senses – vision, audition, olfaction – independently from one another. The assumption was that we can study various aspects of, say, vision, without paying much attention to the other sense modalities. But recent empirical evidence shows that this has been a mistake: our perceptual processes are normally multimodal – different sense modalities influence each other in various ways. The a...

Project

International Neuroinformatics Coordinating Facility. (INCF) Historic

University of Antwerp

This is a fundamental research project financed by the Research Foundation - Flanders (FWO). The project was subsidized after selection by the FWO-expert panel.

Project

International Photonics Access and Research Center (iPARC@VUB)

Vrije Universiteit Brussel

The main objective is to enable the assembly and integration of optical and optoelectronic components with micro-electronic, micro-electronic-mechanic, and micro-fluidic components. As such it will be possible to engineer photonics-enhanced micro-systems that feature novel functionalities and that can be made available to everyone at low cost. These photonic microsystems can then support a variety of research domains, be deployed in inter-disciplinary research, or supply newly-opened economic...

Project

International place of death study Recently ended

Vrije Universiteit Brussel

Demographic and cultural changes will increasingly confront health care systems with the care needs of dying people. According to the WHO, the delivery of appropriate palliative care has grown into a major public health issue. Regardless the aspiration of many to die at home, in Belgium, a majority of patients die in hospital and many are, often unnecessarily, transferred to hospital near the end of life. More systematic knowledge regarding place of death and end-of-life hospitalization is ne...

Project

International remittances and poverty reduction in the Philippines: evidence from the community-based monitoring system (CBMS) data?

University of Antwerp

The research aims to analyze international remittances and poverty reduction in the Philippines using the community-based monitoring system data (CBMS). It aims to determine the extent remittances can raise incomes and alleviate poverty among households by analyzing the existing household-level data from CBMS.

Project

International research in political sciences. Recently ended

University of Antwerp

This project represents a research contract awarded by the University of Antwerp. The supervisor provides the Antwerp University research mentioned in the title of the project under the conditions stipulated by the university.

Project

International research seminar in the series "Antwerp Chapters". Historic

University of Antwerp

This project represents a formal research agreement between UA and on the other hand a private institution. UA provides the private institution research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

International symposium : Multilingual neuroimaging research in Brussels and Europe- state of art and policy implications (22 september 2006 in Mariott Hotel Brussels)

Vrije Universiteit Brussel

The goal of this symposium is to offer a platform for neuroimaging research and research on bi/multilingualism and its possible implications for scientific and educational policy. A state of the art of neurocognitive research on bilingualism will be presented. Scientists and policy makers are given the opportunity to enter into a debate about the subject.

Project

International technological diffusion and productivity impact of R&D Historic

Vrije Universiteit Brussel

This project analyses the importance of comercially oriented domestic and foreign R&D for explaining the evolution of countries' productivity. Cross-section analyses are undertaken at various levels of aggregation with respect to a set of OECD countries during the youngest three decades. Estimations are made of the elasticity of total factor productivity with respect to domestic and foreign R&D capital, as well as of the corresponding rates of return on R&D expenditure. The possible occurance...

Project

International trade and economic development in the Austrian Netherlands, 1759-1791. Historic

University of Antwerp

My project, titled "International trade and economic development in the Austrian Netherlands, 1759-1791", means to initiate a study of the so far disregarded dialectic relationship between international trade and the economic growth of the Austrian Netherlands in the second half of the eighteenth century. I will investigate the impact of international trade and the trade policy on a number of economic sectors in order to reveal the different actors and effects. On the one hand it aims to deli...

Project

International trade and economic development in the Austrian Netherlands, 1760-1790. Recently ended

University of Antwerp

With this research we intend to study the impact foreign trade exerted upon the eighteenth-century economic development of the Austrian Netherlands. On the basis of documents generated by the Council of Finance (Department of Custom Duties) a comprehensive reconstruction and interpretation of the foreign trade and foreign trade policy is envisaged.

Project

International Trade: threats and opportunities in a globalized world. Historic

University of Antwerp

The aim of the conference is to bring together high quality academic papers that analyze the interactions between the new wave of globalization and the real economy of developed countries, and especially contributions that study the determinants and consequences of participation to international trade and foreign direct investments. The fragmentation of the production processes across the world has resulted in a massive increase in the vertical trade of parts and components and has given rise...

Project

International training in food safety, quality Assurance and risk analysis

Ghent University

The ITP Food Safety is covering different aspects of food safety (microbiological, chemical and physical hazards) and the possibilities to control these hazards along the agri-food chain. In this frame, different tools are disseminated e.g. Codex Alimentarius guidelines, implementation of Food Safety Management Systems based on Pre Requisite Programs and HACCP principles but also international acknowledge quality assurance standards as ISO 22000 and Global G.A.P. The concept of risk analysis ...

Project

International training in food safety, quality Assurance and risk analysis

Ghent University

The ITP Food Safety is covering different aspects of food safety (microbiological, chemical and physical hazards) and the possibilities to control these hazards along the agri-food chain. In this frame, different tools are disseminated e.g. Codex Alimentarius guidelines, implementation of Food Safety Management Systems based on Pre Requisite Programs and HACCP principles but also international acknowledge quality assurance standards as ISO 22000 and Global G.A.P. The concept of risk analysis ...

Project

International workshop on principles of software evolution. Historic

University of Antwerp

The International Workshop on Principles of Software Evolution (IWPSE) is the flagship workshop for research on software evolution and as such it is the prime candidate for publishing the end results of the RELEASE project. Several members of the RELEASE network are part of the organization committee and we agreed to have a special slots devoted solely to RELEASE results. Several members of the network submitted papers and six of them have been accepted after rigorous reviewing by the program...

Project

Internet-panel local elections 2006. Historic

University of Antwerp

Gelieve aan te vullen a.u.b.

Project

Internet panel municipal elections 2006. Historic

University of Antwerp

Internet panel municipal elections 2006.

Project

Internship agreement Katsuyuki Maeno Fabrication and evaluation of pillar array columns for liquid chromotography Recently ended

Vrije Universiteit Brussel

The research institute 'VUB' and the 'Shiseido Company, Limited' have entered into a service-agreement concerning the project' Internship agreement'. The research results can be transferred to the company, there can be a reasonable return in case of commercialisation or there is another kind of agreement on intellectual property, as outlined in the concluded agreement.

Project

Interoperability Middleware for Wireless Sensor Networks

KU Leuven

21st century objectives such as smart cities require sensing at massivescale. To cost effectively realize massive-scale sensor networks, we advocate for the integration of purpose-deployed sensor networks with consumer mobile devices (such as smartphones and web pads) and humans actors. To realize this vision, a common middleware is required that allows humans and heterogeneous nodes with different hardware resources, network media and software stacks to be composed into coherent distributed ...

Project

Interoperable Sensor Networks (ISN) Recently ended

Vrije Universiteit Brussel

The goal of the European ISN project is the creation of a semantic interoperable platform based on a wireless sensor network, and to test and validate this platform on a selected set of vertical applications. The aim is to expand the application platform from the Leonardo platform to a wireless sensor world and secondly to valorise its power to a real-world wireless sensor context.

Project

Interpersonal communication training of natural language interaction with autonomous virtual characters (deLearyous). Recently ended

University of Antwerp

The goal of the deLearyous project is to develop an interactive serious 3D-game for training interpersonal communication skills in a professional context, e.g., employer-employee or customer-seller relations. The game allows trainees to interact woth virtual autonomous characters who react in a realistic and expressive way to the input of the trainee. In this way, the trainee can exercise different behavioural patterns and roles in a safe virtual environment. The role of CLiPS in the project ...

Project

Interplay between atomic layers and functional adsorbates

Universiteit Hasselt

Graphene is a non-magnetic, two-dimensional semimetal, which can be turned into an n- or p-type conductor by gate voltages. This results in unusually high charge carrier mobilities with mean free paths of several microns. The carriers follow a linear dispersion relation where the energy is proportional to the wave number, a behavior that is expected for massless particles such as photons. Within this project, we consider graphene in an electronic- and magnetic sense as a 'blank page', which w...

Project

Interplay between atomic layers and functional adsorbates

Universiteit Hasselt

Graphene is a non-magnetic, two-dimensional semimetal, which can be turned into an n- or p-type conductor by gate voltages. This results in unusually high charge carrier mobilities with mean free paths of several microns. The carriers follow a linear dispersion relation where the energy is proportional to the wave number, a behavior that is expected for massless particles. Within this project, we consider graphene in an electronic- and magnetic sense as a 'blank page', which will be modified ...

Project

Interplay between atomic layers and functional adsorbates.

University of Antwerp

Graphene is a non-magnetic, two-dimensional semimetal, which can be turned into an n- or p-type conductor by gate voltages. This results in unusually high charge carrier mobilities with mean free paths of several microns. The carriers follow a linear dispersion relation where the energy is proportional to the wave number, a behavior that is expected for massless particles. Within this project, we consider graphene in an electronic- and magnetic sense as a 'blank page', which will be modified ...

Project

Interplay between chemical reactivity and aromaticity: theoretical developments and application to large aromatic carbon compounds: from cyclacenes to graphene nanoribbons

Vrije Universiteit Brussel

Aromaticity as a key concept in chemistry, is a very useful quantity in the rationalisation of structure, stability and reactivity of many molecules.[1,2] This property is associated with the cyclic delocalization of electrons, resulting in extra stabilization in the case of aromatic compounds and destabilization in the case of antiaromatic compounds. Several criteria have been put forward to quantify this property, which can roughly be divided into energetic, geometrical, electronic, magneti...

Project

Interplay between dynamics of the atomic structure and confinement of electrons and spins.

KU Leuven

In this project, we will investigate the interplay between atomic vibrations on the one hand and electronic and magnetic properties on the other hand, specifically elucidating the role of confinement at the nanoscale. In three work packages, we will deal with: (i) the characteristics of phonon confinement when going from two-dimensional tozero-dimensional objects. Specifically, we will search for confinement-induced shifting and (dis)appearance of and changes in specific modes. We will also d...

Project

Interplay between microRNAs and oncogenic networks in T-cell acute lymphoblastic leukemia (miRtalL)

Ghent University

In this project, we aim to elicudate the role of miRNAs in normal and malignant T-cell development. MiRNA will be integrated in the network of known oncogenes and tumor suppressor genes involved in T-cell leukemia. Eventually, these findings can identify novel therapeutic targets in this disease.

Project

Interplay between peroxisome biogenesis and redox balance in mammalian cells. Recently ended

KU Leuven

justify;text-justify:inter-ideograph;text-indent:1.0cm;line-height:150%">mso-bidi-font-family:'Times New Roman';mso-bidi-theme-font:minor-bidi">Peroxisomenzijn multifunctionele celorganellen met een breed spectrum aan functies.Momenteel zijn er steeds meer en meer indicaties dat veranderingen inperoxisoomfunctieook gekoppeld kunnen worden aan cellulaire veroudering enouderdomsgerelateerde ziekten. De moleculaire mechanismen die ten grondslagliggen aan deze fenomenen zijn nog niet gekend. Gedu...

Project

Interplay between progranulin and tdp-43 in the pathogenesis of frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

KU Leuven

Frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are two neurodegenerative disorders that overlap at the clinical, genetic and pathological level. Although the majority of patients with FTLD or ALS present without a positive familial history, familial forms of both disorders are not rare. Clinically, some patients with FTLD suffer from motor neuron degeneration as seen in ALS and some patients with ALS have cognitive impairments. Loss of function mutations in t...

Project

Interplay between vitamin C and glucose metabolism in plant and animal mitochondria. Historic

University of Antwerp

Interplay between vitamin C and glucose metabolism in plant and animal mitochondria.

Project

Interplay of RNA polymerase molecules, regulatory processen and DNA topology at the tandem pair of promoters directing the transcription of the carbamoylphosphate synthase operon carAB of Escherichia coli. Historic

Vrije Universiteit Brussel

Transcription of the carAB operon encoding the unique carbamoylphosphate synthase of E. coli is initiated at two promoters in tandem. The downstream promoter P2 is mainly regulated by arginine and the arginine repressor ArgR. Initiation at the upstream promoter P1 is repressed by pyrimidines and purines. In order to better understand regulation of carAB transcription initiation we will make an elaborate study of the P1 and P2 activities in vivo and in vitro. Mutations will be introduced to: (...

Project

Interplay of RNA polymerase molecules, regulatory processes and DNA topology at the tandem pair of promoters directing the transcription of the carbamoylphosphate operon carAb of Escherichia coli Historic

Vrije Universiteit Brussel

The carAB operon encodes the unique carbamoyl phosphate synthase of Escherichia coli. Transcription of this operon occurs in function of the needs for carbamoyl phosphate, a precursor common to the de novo synthesis of arginine and pyrimidine nucleotides. With its two promoters and numerous targets for DNA-binding regulatory proteins and the diversity of regulatory mechanisms [arginine, purine and pyrimidine-specific repression, UTP-dependent reiterative transcription initiation (stuttering) ...

Project

Interplay of RNA polymerase molecules, regulatory processes and DNA topology at the tandem pair of promoters directing the transcription of the carbamoylphosphate synthetase operon carAB of Escherichia coli Historic

Vrije Universiteit Brussel

The carAB operon encodes the unique carbamoyl phosphate synthase of Escherichia coli. Transcription of this operon occurs in function of the needs for carbamoyl phosphate, a precursor common to the de novo synthesis of arginine and pyrimidine nucleotides. With its two promoters and numerous targets for DNA-binding regulatory proteins and the diversity of regulatory mechanisms [arginine, purine and pyrimidine-specific repression, UTP-dependent reiterative transcription initiation (stuttering) ...

Project

Interpretable clinical decision support systems.

KU Leuven

Clinical decision support (CDS) systems mimicking the clinical work flow are more likely to be used in clinical practice.nbsp;As a result, variables are often categorized before or after modeling in order to improve interpretability.nbsp;Other CDS systems focus on modelingaspects, reducing their use in clinical practice.nbsp;This research will improve current methods and formulate new alternative models tocontrol the possible loss of information due to categorization.nbsp;The modeling aspects...

Project

Interpretation by measuring, modelling and identification III Historic

Vrije Universiteit Brussel

The IMMI project is focused on the development of measurement techniques (measuring, modelling, identification) and measurement equipment to be used to gather the required information. Instrumentation evolved towards a common architecture: an analogue front end, analogue to digital converter, signal processing hardware and some capability to connect a computer network. Because of this evolution modular measurement systems became reality (VME, VXI, MMS, PC cards...). The technical elements do...

Project

Interpretation by measuring, modelling and identification - part II. Historic

Vrije Universiteit Brussel

Over the years, the measurement problem became more sophisticated. Nowadays measuring is a complex process consisting of three main steps: the design of an expezriment, the building of a model for the studied problem and the estimation (=measuring) of the parameters involved in the model. To get a maximal efficiency, it is necessary to integrate all these activities in a single approach. Maximal efficiency can be translated as minimal measuring time, maximal accuracy, minimal cost,...dependin...

Project

Interpretation of contracts.

KU Leuven

Contracts arenegotiated on the basis of the facts known at the moment when they areconcluded. Yet, between the conclusion and the execution of an agreement,external circumstances often evolve. In such cases different legal conceptions,such as force majeure, hardship and abuse of the law, might be called upon, butnone of them are adequatein Belgian law. Including hardship- or MAC-clauses inthe contract can also be an outcome. But what happens in cases where no forcemajeure or abuse of law can ...

Project

Interpretation of FT-IR spectra Recently ended

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Datwyler Pharma. The research institute TANC provides Datwyler Pharma research results on 'Interpretation of FT-IR spectra' under the conditions as stipulated in the present contract.

Project

Interpretations if Islam as levers for the emancipation of Muslim Women. Historic

University of Antwerp

This research reveals to us that social change is occuring in Muslim communities in relation to the position of women. In debates on transnational religion and migration, the emphasis has thus far always been on male migrants who are active in religious and political movements. The present research project focuses on women and their role in the development of new relationships within Sunni Islamic orthodoxy, a topic that is also relevant to the shaping of opinions on Islam.

Project

Interpretations Kruibeke field measurements in the Scheldt in the period 1995-1998 and 2002-2005. Historic

Vrije Universiteit Brussel

Interpretations Kruibeke field measurements in the Scheldt in the period 1995-1998 and 2002-2005.

Project

Interpreting soil chemical analyses of soil samples from various nature reserves in the province of Drenthe. Recently ended

University of Antwerp

This project represents a formal research agreement between UA and on the other hand Prov. Drenthe. UA provides Prov. Drenthe research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

Interpret Study Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties CENSTAT (research institute at Hasselt University), and on the other hand, Medtronic. The research institute CENSTAT provides Medtronic research results on 'Interpret study' under the conditions as stipulated in the present contract.

Project

Interpret study (2 parts) Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties CENSTAT (research institute at Hasselt University), and on the other hand, Medtronic. The research institute CENSTAT provides Medtronic research results on 'Interpret study (2 parts)' under the conditions as stipulated in the present contract.

Project

Inter-relations of protein Tau, GSK3 and Nectin-3in synaptic structure and plasticity in the hippocampusof mouse models for Alzheimer's disease Recently ended

KU Leuven

Alzheimer’s Disease (AD) is the most common subtype of dementia, first studied by Alois Alzheimer and published in the beginning of the 20th century. He described for the first time the connection between clinical observations of dementia during life and post-mortem analysis of brain, revealing the two main pathological hallmarks: amyloid plaques and neurofibrillary tangles. The difficulty to understand AD results from the immense complexity of our brain, combined with the many factorsthat in...

Project

Inter-Religious Peace Education for Development in Northern Ghana: Youth as Agents

KU Leuven

In this research work, we focus on the Northern part of Ghana that is known to suffer pain, loss, poor educational standards, poor health services and hunger, due to severe interreligious and intercultural violence and conflicts that characterise the area. If development is to be fuelled, there is first the need to work towards peace. Therefore, we need people who are able to tolerate, respect, dialogue, appreciate one another,and thereby unite and cooperate to work for the common good of all...

Project

Interruption of transmission of poliovirus circulation in the end-stage of polio-eradication and beyond, using recombinant antibody-derived proteins as antiviral drugs Recently ended

Vrije Universiteit Brussel

Interruption of transmission of poliovirus circulation in the end-stage of polio-eradication and beyond, using recombinant antibody-derived proteins as antiviral drugs

Project

Intersections and identifications in media use: ethnicity, sexuality and generations.

University of Antwerp

This project aims to investigate the intersection of different sources of identification as mentioned above: nationality, ethnicity and sexual orientation. Theoretically, it aims to explore and develop parallels in thinking on these three fields, focusing in particular on the uneasy relation between ethnic and sexual 'minority' status in a particular national context. Empirically, it aims to do this through in-depth qualitative research on the media uses and identifications of migrant and eth...

Project

Intersections of Cultural Memory and Human Rights: The Case of Dave Eggers

Ghent University

This project examines the interrelations between cultural memory and human rights via a comprehensive and systematic analysis of the work of the contemporary American author Dave Eggers, which encompasses bestselling novels, collaboratively produced testimonies, publishing ventures, and social activism.

Project

Interstellar dust in Virgo Cluster elliptical galaxies Recently ended

Ghent University

Together with some 20 other intitutes, the UGent has initiated a project to map the Virgo Cluster, the most nearby galaxy cluster, at infrared and submm wavelengths in the frame of a Herschel Key programme. The goals of this project is to model existing and new data on some 100 elliptical galaxies in the Virgo Cluster with state-of-the-art Monte Carlo radiative transfer simulations. This will allow us to determine the mass, temperature distribution and spatial distribution of the interstellar...

Project

Interstitial fibrosis in protocol biopsies of renal allografts: a prospective, randomized trial of sirolimus versus cyclosporine (FIBRASIC). Historic

University of Antwerp

This clinical-fundamental research intends to study the role of epithelial to mesenchymal transition in the development of interstitial fibrosis in the renal allograft. This study will be performed on 100 implantation biopsies and 100 protocolbiopsies of renal allografts (6 months post transplantation). The renal biopsies will be retrieved from patients, included in a prospective, multicentric, randomized trial, conducted by Prof. J-L. Bosmans ( Department of Nephrology, University Hospital A...

Project

Intertextuality and flows of information. Historic

University of Antwerp

Linguistic analysis of the way in which meanings are generated and transformed in information flows in the context of globalization. The specific focus is on intertextual processes approached from the point of view of ethnographically supported pragmatics-based ideology research, concentrating on the variable use of implicitness and differences in reference to sources. The case to be investigated will be taken from the international printed media in English, the Flemish printed media, and the...

Project

Intertextuality in Primo Levi. Historic

University of Antwerp

This project intends to establish an overview, as complete as possible, of the intertextuality in Primo Levi's works. In the first place the part intertextuality plays in the holocaust testimony will be examined in depth: the appearance of literary authorities in the framework of a 'unique' drama leads to a historicization of the events. Furthermore, the intertextuality discovered in Levi's works serves as a case for the intertextuality practice: in Levi's works a permanent tension is at work...

Project

Interuniversitaire master in Water Resources Engineering Historic

Vrije Universiteit Brussel

Organisation of the interuniversity program - Master in Water Resources Engineering - in collaboration with the KU Leuven

Project

Interuniversitary Foreing Francque-Leerstoel for Pr. John Dermott-Devine

Vrije Universiteit Brussel

Interuniversitary Foreing Francque-Leerstoel for Pr. John Dermott-Devine

Project

"Interuniversitary Program (ICP) Molecular Biology" (2009-2010). Historic

Vrije Universiteit Brussel

"Interuniversitary Program (ICP) Molecular Biology" (2009-2010).

Project

Interuniversity 700 MHz field NMR infrastructure as a high technological research instrument in biotechnological, chemical and materials sciences. Historic

University of Antwerp

Interuniversity 700 MHz field NMR infrastructure as a high technological research instrument in biotechnological, chemical and materials sciences.

Project

Inter-university collaboration for building a Belgian Biobank network. Historic

Vrije Universiteit Brussel

The present application aims at pursuing the development of a human Biobank network among the consortium of eight Belgian university hospitals to streamline research opportunities on human materials. This applications aims (i) at implementing convergent SOPs for tissue collection and processing, local databases, legal and ethical rules, and (ii) at linking together Belgian University hospitals through a catalogue software presenting an inventory of samples available for National research purp...

Project

Interuniversity collaborative study Oral health dataregistration.

KU Leuven

In this pilot project pre-liminary work was undertaken in order to develop a system that allows the collection, analysis and interpretation of information relevant for the oral health condition of the belgian population. The project comprises the development of necessary instruments (questionnaires, clinical examination), informative documents regarding the registration and the necessary contacts with relevant instances. The project is an initiative of the RIZIV-INAMI and is carried out by an...

Project

Interuniversity Master in Water Resources Engineering Historic

Vrije Universiteit Brussel

Organisation of the interuniversity program - Master in Water Resources Engineering - in collaboration with the KU Leuven

Project

Interuniversity Programme in Water Resources Engineering Historic

Vrije Universiteit Brussel

The objective of the Interuniversity Programme in Water Resources Engineering (IUPWARE) is to provide multi-disciplinary and professional training in water resources engineering, and to equip future personnel with the necessary technical and managerial knowledge and skills which they will require to successfully design and operate water resources schemes. The foregoing is particularly important for personnel from developing countries where sustainable development of water resources is more cr...

Project

Interuniversity Programme in Water Resources Engineering Historic

Vrije Universiteit Brussel

The objective of the Interuniversity Programme in Water Resources Engineering (IUPWARE) is to provide multi-disciplinary and professional training in water resources engineering, and to equip future personnel with the necessary technical and managerial knowledge and skills which they will require to successfully design and operate water resources schemes. The foregoing is particularly important for personnel from developing countries where sustainable development of water resources is more cr...

Project

Interuniversity Programme ‘Master of Science in Food Technology 2011-2012’ Recently ended

Ghent University

Two-year programme organised by UGent and KU Leuven to provide students from developing countries with a training in food science, food technology and food engineering

Project

Interuniversity programme Molecular Biology.

KU Leuven

Het aanbieden van een theoretische en praktische opleiding in de moleculaire biologie aan jonge wetenschappers uit ontwikkelingslanden, die betrokken zijn bij het onderwijs/onderzoek in de humane geneeskunde, dierlijke productie of plantaardige productie. Het opleiden tot bekwame, kritische en zelfstandige wetenschappers die in staat zijn om, met de opgedane kennis, via hun taken in het onderwijs, het onderzoek op beleidsniveau, bij te dragen tot de verdere ontwikkeling van hun land.

Project

Interuniversity Programme Physical Land Resources Historic

Vrije Universiteit Brussel

Organisation of the interuniversity program - Master in the Physical Land Resources - in collaboration with the UGent

Project

Inter-university Research Center for Multi-frequency pulsed Electron paramagnetic resonance spectroscopy. Recently ended

University of Antwerp

This project represents a research contract awarded by the University of Antwerp. The supervisor provides the Antwerp University research mentioned in the title of the project under the conditions stipulated by the university.

Project

Interuniversity vocational training of family doctors Historic

Vrije Universiteit Brussel

The post graduate training for family doctors is done jointly by the four Flemish universities. Specific division of the tasks is agreed. Ihe part of the V.U.B. is the agogical training of the.animators of the local group of 10-15 doctors and also the didactical and medical supervision of the teaching modules.

Project

Interval approaches to include non-determinism in midfrequency vibro-acoustic models.

KU Leuven

The objective of the proposed PhD project is to account for non-determinism in the wave based modelling concept by introducing the concept of interval description. Intervals will be defined on the geometrical and damping parameters of a vibro-acoustic system and the subsequent intervalson the resulting dynamic response will be calculated. Research efforts will focus on the development of numerical methods and on validation on representative academic as well as industry-relevant vibroacoustic ...

Project

Intervention after alarm measurement port Recently ended

Universiteit Hasselt

This offer represents a formal service agreement between the parties NuTeC (research institute at Hasselt University), and on the other hand, Croes BVBA. The research institute NuTeC provides Croes BVBA research results on 'Intervention after alarm measurement port' under the conditions as stipulated in the present contract.

Project

Intervention in young children with an autism spectrum disorder Recently ended

Ghent University

The aim of this study is to map the treatment services in Flanders for young children (between two and five) with an autism spectrum disorder. Treatment centers are asked to fill out questionnaires about the treatment methods and goals that are being used in this population.

Project

Interventions for improving adherence to treatment recommendations in people with type 2 diabetes mellitus. Historic

University of Antwerp

Interventions for improving adherence to treatment recommendations in people with type 2 diabetes mellitus.

Project

Intestinal immune induction following targetting on soluble antigens to aminopeptidase on enterocytes : nature of antigens, role of enterotocytes and intestinal dendritic cells

Ghent University

Firstly, the interaction of antigen and the APN receptor is studied using polymeric and monomeric F4, and antibodies against APN, and endocytosis and transcytosis will be analysed in APN expressing cells. Secondly the early cytokine signals by the enterocytes and DCs following contact with these different antigens is studied.

Project

Intestinal perfusion with mesenteric blood sampling in mice as an innovative biopharmaceutical drug evaluation tool. Recently ended

KU Leuven

The present research proposal pursues to develop a novel preclinical tool to better understand mechanisms underlying intestinal drug disposition and to explore drug-drug interactions as early as feasible during the drug discovery process. HIV protease inhibitors have been selected as model compounds. In situ intestinal perfusion with mesenteric blood sampling in rodents will be used to investigate intestinal absorption mechanisms. Extending the intestinal perfusion technique from rats to mice...

Project

Intestinal toxicity and oral resorption of conjugated Fusarium mycotoxins, frequently present in feed and food

Ghent University

The objectives of this study are threefold and are: 1) the synthesis of glucosyalted deoxynivalenol and zearalenone conjugates and acetylated deoxynivalenol derivates, in sufficient quantity to conduct futher in vitro an din vivo experiments; 2) the study of the intestinal cytotoxicity and influence on cytokine response of these derivates; 3) to gain insight in the oral bioavailability and in vivo degree of hydrolysis of these synthetised conjugates using relevant in vitro models with intesti...

Project

In the European ESPRIT project Web for Schools (WfS), the applicability of the Internet technology within the secundary education system is explored. Historic

Vrije Universiteit Brussel

The web for schools project seeks to contribute substantially to the creation of the Information Society by preparing the ground for a concerted effort to establish a communtiy of teachers all over Europe, ultimately large enough for self-sustained growth, who are able in terms of skills and infrastructure to use and contribute to a network of people involved in the production or electronic educational material. In a big experiment (150 highschools from every European country were equipped w...

Project

In the footsteps of Newton? 's Gravesande Scientific Methodology

Vrije Universiteit Brussel

This proposal will scrutinize W.J. s Gravesande's (1688-1742) scientific methodology, who was one of the most influential advocates of Newtonianism on the Continent. s Gravesande further developed Newton's natural philosophy and dealt with physical problems that were left unaddressed by Newton. Surprisingly, there are few detailed studies of 's Gravesande's methodological views proper and their relevance for his scientific practice. This research project seeks to fill in this scholarly void b...

Project

In the margin… Landscape and biodiversity in the margins of infrastructure in the eurometropolis Lille-Kortrijk-Doornik Recently ended

Ghent University

The project investigates how the network of infrastructural margins in the eurometropolis Lille-Kortrijk-Doornik can be an element in the green networks in the region Nord Pas de Calais. The research focuses on the biodiversity and the quality of the landscape.

Project

In the mind's eye: does the effect of real versus stylized eye cues on cooperative behavior vary according to context and one's intrinsic motivation? A behavioral and fMRI study.

University of Antwerp

The project proposes to investigate the neural processes along with the contingencies that underlie the relation between eye cues and cooperative behavior in social dilemmas. We differentiate between real and stylized, (iconic) eye cues, and we propose that only the former provide social information and are capable of eliciting trust by affecting the brain's social cognition system (temporo-parietal junction, medial frontal cortex, and amygdala), while the latter, inducing a feeling of being...

Project

In the wheel of Odiel / From brush puller till cyclist, Phase 1 Historic

Universiteit Hasselt

The main objective of this project is to strengthen the cooperation between the Brush and Shoe Museum in Izegem and the Cycle Museum in Roeselare and developing a genuine educational value of those collections and the underlying regional history to the specific target group of BSO and TSO education. This project will create an entirely different museum experience, taking into account that the museum walls are broken and boundaries between the different subjects are becoming blurred. The proje...

Project

In the wheel of Odiel / From brush puller till cyclist, Phase 3 Historic

Universiteit Hasselt

The main objective of this project is to strengthen the cooperation between the Brush and Shoe Museum in Izegem and the Cycle Museum in Roeselare and developing a genuine educational value of those collections and the underlying regional history to the specific target group of BSO and TSO education. This project will create an entirely different museum experience, taking into account that the museum walls are broken and boundaries between the different subjects are becoming blurred. The proje...

Project

Intracellular compartimentalisation of the signal transduction of 5-HT4-receptors in cardiac and gastro-intestinal tissue Recently ended

Ghent University

The signal transduction involved in the positive inotropic and chronotropic answer to stimulation of the 5-HT4-receptors on the cardiac myocytes is investigated, in particular the intracellular compatimentalisation through phosphodiesterases and protein kinase A anchoring proteins (AKAPs). In the colon this is evaluated for the different cell types possessing 5-HT4-receptors (cholinergic neurons, nitrergic neurons, smooth muscle cells).

Project

Intracellular P-type pumps implicated in heart failure and Parkinson disease. Recently ended

KU Leuven

Members of the P-type ATPase family are molecular pumps involved in essential physiological processes such as muscle contraction and neuronal excitation. We aim to characterize at the molecular level representativesof two subfamilies of the P-type ATPases playing significant roles in human diseases of the heart and brain. A) A reduced activity of the cardiac SERCA2 Ca2+ pump contributes to the diminished contractility of the failing heart. By analyzing the structure-function relationship, we ...

Project

Intracellular study of coincidence detection in the auditory brainstem.

KU Leuven

Hearing is a sense that excels in the speed of its processing. Its consitutent cells show many specializations to analyze the rapid changes in pressure that constitute sounds. One aspect of hearing that has been particularly well-studied with regards to speed of processing, is the localization of sounds in space. Humans localize sounds along the horizontal plane predominantly on the basis of the tiny differences in arrival timebetween the left and right ear: differences as small as 10 microse...

Project

Intracytoplasmic sperm injection. Historic

Vrije Universiteit Brussel

The aims of the project are to investigate the use of immotile spermatozoa in ICSI, and to select, characterize and cryopreserve testicular spermatozoa for ICSI. So far, ICSI with immotile spermatozoa is less efficient than with motile spermatozoa, since motility is treated as a marker for vitality. Other parameters which might predict successful use of immotile spermatozoa will be studied. Vital immotile spermatozoa may be distinguished from non vital spermatozoa by various procedures, such ...

Project

Intra-industry benchmarking of discretionary disclosure content in corporate reporting.

University of Antwerp

We investigate intra-industry imitation in discretionary financial disclosure and management commentary. Imitation of discretionary reporting content and related reporting choices may be conceived as a rational response to discretion and related ambiguity in order to meet explicit and implicit industry norms. This issue is crucial in the current debate on a principles-based versus rules-based approach in the reporting standard-setting process. Neo-institutional theory suggests that more ambig...

Project

Intraocular electro-optic lens with focus control for cataract patients

KU Leuven

The optical function of the human eye is based on the combination of the cornea, an adjustable lens and the vitreous fluid. The accommodation of the eye, which is meant to focus an image, is based on the movement ofthe ciliary muscle, which alters the shape and thus dioptric strength of the adjustable lens. In the case of cataract disease, the adjustable lens becomes milky, causing blurred vision. The most common cure is to surgically replace the natural lens by a static artificial one. Howev...

Project

Intraoral digital subtraction radiography, and its application to caries detection. Historic

Vrije Universiteit Brussel

While in most western countries the prevalence of caries has decreased in the past decades, clinical diagnosis by visual examination has become more problematic. These findings are indicative of the difficulties that exist among present populations in detecting carious lesions that may progress into dentin without a macroscopically visible enamel surface breakdown. In recent years, bitewing radiography has been considered as a significant adjunct to clinical examination. However, the effectiv...

Project

Intraperitoneal gene delivery of to prevent the formation and growth of peritoneal metastases: nanoparticle optimization and development of a thermosensitive hydrogel

Ghent University

Intraperitoneal non-viral nucleic acid delivery is attractive to target peritoneal metastases. We aim to evaluate the stability and aggregation non-viral gene complexes in the peritoneal fluid, by using Fluorescence Fluctuation Spectroscopy and Single Particle Tracking. Also, we aim to develop a thermosensitive hydrogel formulation for delivery of nucleic acids in the intraperitoneal cavity during a prolonged period of time.

Project

Intravascular fluorescence life-time imaging of the vulnerable plaque

Vrije Universiteit Brussel

We aim in this project to improve the current intravascular imaging modalities by combining anatomical information with molecular characterization. Hereto, fluorescent tracers will be used directly at different biomarkers of vulnerable plaques. For the detection of the fluorescent signal bound to the atherosclerotic lesions, a new intravascular detector will be designed, which will be combined with an intravascular ultrasound catheter for structural information.

Project

Intrinsically disordered chaperones: substrates in vivo and mechanism in vitro

Vrije Universiteit Brussel

Intrinsically disordered proteins were first defined in the late 90's [1, 2], as segments or even full-length functional proteins that do not attain a stable three dimensional conformation, rather have several dozen conformations in a dynamic equilibrium with each other [3]. IDPs have a special amino acid composition, they are highly charged with low hydrophobic character, according to which they cannot form a stable fold and an active centrum necessary for e.g. enzyme activity. Their functio...

Project

Intrinsic Catalytic Kinetics Analyzed and Reconciled with Industrial Conditions (ICKARUS) Recently ended

Ghent University

This project aims at elucidating the reaction mechanism of propane dehydrogenation over novel Pt-Ga/Mg(Al,Ga)Ox catalysts via advanced kinetic and spectroscopic techniques, including Temporal Analysis of Products (TAP) and Diffuse-Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS).

Project

Introducing permanent hydrophilic / hydrophobic surface during the extrusion of yarns & straps. Historic

University of Antwerp

Introducing permanent hydrophilic / hydrophobic surface during the extrusion of yarns & straps.

Project

Introducing PPI-iMixPro, a novel technology to characterize protein complexes

Ghent University

Proteins typically function in concert with other proteins and thus form larger protein complexes. Mass spectrometry is a key technology to identify the individual components of these protein complexes. In this project, differential stable isotope labeling of proteins or peptides will be used to characterize the constellation of protein complexes with higher accuracy.

Project

Introducing provider-patient communication as a new topic for training and research at health institutes in Cochabamba (Bolivia) and Cuenca (Ecuador) Recently ended

Ghent University

The objective is to promote communication skills of health professionals. The project aims to awake interest among the local actors and to create favorable conditions for progressing towards the integration of the communication theme into the academic program namely by 1) identifying, motivating and training pioneers in each city, 2) supplying tools and background information, 3) implementing training activities, 4) carrying out research, 5) disseminating results and experiences and 6) creati...

Project

Introducing redundancy into numerical algorithms: computing with frames

KU Leuven

Computational schemes for approximating functions or for solving differential and integral equations typically require the discretisation of continuous functions in a finite-dimensional space. Popular choices of basis functions in one dimension include polynomials, Fourier series, splines and wavelets. However, bases are exceedingly difficult to construct on domains or manifolds in higher dimensions with complicated geometry. There, the only viable option is to use piecewise low-order polynom...

Project

Introductie van de sojateelt in Vlaanderen

KU Leuven

Vlaanderen is voor de eiwitvoorziening in diervoeding sterk afhankelijkvan de import van soja uit Zuid-Amerika. Deze invoer roept maatschappelijke en ecologische vragen op, en door de hoge marktprijs voor soja zijnde economische gevolgen voor Vlaamse landbouwers groot. Aangezien alternatieve eiwitgewassen geen volwaardige vervangers voor soja in het voederrantsoen zijn, zou de introductie van de sojateelt in Vlaanderen een interessante optie voor verschillende doelgroepen zijn. Deze introduct...

Project

Introduction of analystical separation techniques in the virology to resolve interactions in molecular field close to picornaviridae. Historic

Vrije Universiteit Brussel

Study of the analystical separation techniques in the virology to resolve interactions in molecular field close to picornaviridae.

Project

Introduction of analytical separation techniques in virology to clarivy interactions at the molecular level in picornaviridae. Historic

Vrije Universiteit Brussel

When the research group of Dieter Blaas (Vienna, Austria) in 1999 used for the first time capillary electrophoresis (CE) to demonstrate viral interactions at the molecular level (in this case, rhinovirus), it was at that time almost fifty years ago that new analytical separation techniques were introduced in virology. The research group (MICH) at that time also felt the need for new separation techniques in their lab, in order to achieve their objectives. In order to solve this problem, a co...

Project

Introduction of analytical separation techniques in virology to study interaction at the molecular level of picornaviridae Historic

Vrije Universiteit Brussel

Using a cell-free system for the production of virus material and CE as separation technique, we want to study some unsolved issues regarding the structure and replication of picornaviruses, such as the function of some viral proteins, the mechanism of initiation of protein- and RNA-synthesis, and the different steps in the morphogenesis. It should also enable us, besides the above-mentioned topics : (i) to detect subviral particles formed during the replication cycle of picornaviruses (morph...

Project

Introduction of chemical analysis in microbiology to elucidate interactions at the molecular level of the poliovirus Historic

Vrije Universiteit Brussel

Using a cell-free system for the production of virus material and capillary electrophoresis as separation technique, some unsolved issues regarding the structure and replication of picornaviruses, such as the function of some viral proteins, the mechanism of initiation of protein- and RNA-synthesis, and the different steps in the morphogenesis will be studied. It should also enable, besides the above-mentioned topics, (i) to detect subviral particles formed during the replication cycle of pi...

Project

Introduction of methods for cultivation and phenotypic characterization of primary osteoclasts and osteoblasts. Historic

University of Antwerp

The aim of this project is to introduce some of the basic methodologies indispensable in the field of bone research. On the one side, this will include cultivation of osteoclasts and osteoblasts starting from respectively human peripheral blood and RAW264.7 cells, and human bone fragments. On the other side, methods will be optimized to phenotypically characterize these cell types allowing us to study cell differentation and functional activity. These techniques will enable us to functionally...

Project

Introductory course development cooperation from a Belgian perspective for managers and staff at the headquarters of BTC. Historic

University of Antwerp

This project represents a formal service agreement between UA and on the other hand BTC. UA provides BTC research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

Intuitive user-guidance for physical simulations.

KU Leuven

Computer graphics is a vast domain within computer sciences which encompasses simulation and visualization of physical effects like the behaviour of fluids, gasses and object interactions such as collisions and deformations. Such simulations are often defined by the underlying laws and equations of physics which leave little control over the outcome of these simulations.In computer graphics one would like to create visuallypleasing simulations which require some form of control for the artist...

Project

In tune with eternity: song and spirituality of the Modern Devotion.

University of Antwerp

The textual culture of the Modern Devotion is more differentiated than previous scholarship has acknowledged, with respect to transmission, production, reception, and content. The project will provide new perspective to the field by developing an innovative view on the pragmatic functionality and the thematic uniqueness of Middle Dutch devotional song, particularly by including sermons and sister books into song research, and by methodological integration. The project aims to expand the estab...

Project

Invasie van pesticidedegraderende bacteriën in zandfilters voor drinkwaterproductie

KU Leuven

Bioaugmentation is a promising remediation strategy, already used in soil remediation. The success of this strategy will however depend strongly on the interactions between the inoculum and the endogenous bacterial community. An interest is rising to use bioaugmentation for removing contaminants from drinking water. In drinking water production, ground- andsurface water is used, which often contains micropollutants like pesticides and degradation products thereof. For elimination of such poll...

Project

Invasion and biodiversity in grasslands and field borders Historic

University of Antwerp

Biological invasions are considered an increasing threat to biodiversity, but the underlying principles are poorly known. Also the way changes in the global climate will affect invasions is not well understood. The aim of the current project is to develop an improved mechanistic framework to (a priori) establish which communities are most susceptible to being invaded (`invasibility') and which species are expected to become invasive (`invasiveness') under given conditions. The project mainly ...

Project

Invasive pulmonary aspergillosis: biomarkers in exhaled breath condensate for early diagnosis and diversity of pathogens involved.

KU Leuven

Invasive pulmonary aspergillosis (IPA) is a life-threatening infection in immunocompromised patients. Early initiation of therapy improves outcome. This implies the necessity of early diagnosis, which is not always feasible due to the fact that invasive procedures (lung biopsy, broncho-alveolar lavage) are often precluded. This project evaluates the use of exhaled breath condensate (EBC) as a matrix for IPA biomarker testing. EBC is collected non-invasively, with potential for repeated sampli...

Project

Invasive seaweeds in rising temperatures: impacts and risk assessments (INVASIVES)

Ghent University

The aim of the project is to assess present and future impacts of invasive alien seaweeds on the North-Atlantic coastal biodiversity. The project aims specifically at predicting the effects of alien seaweeds under climate variability and rising sea surface temperatures [1] in the North-Atlantic. This will be done by addressing temperature effects on expansion rate and range shifts, abundance and ecological functioning of invasive or potentially invasive alien seaweeds.

Project

Inventarisation and layout need study of adapted sports in West-Flanders. Historic

Vrije Universiteit Brussel

Inventarisation and layout need study of adapted sports in West-Flanders

Project

Inventarisation of old dumping sites and abandonned industrial grounds in the province of Flemish Brabant. Historic

Vrije Universiteit Brussel

Detection and location of potential black points - Establishment of a list of identified sites (on the basis of licence files)

Project

Inventory and analysis of portfolios in Flanders. Historic

University of Antwerp

The department of Education of the Flemish government ordered an inventory and an analysis of Flemish portfolios within the domain of Accreditation of Prior Learning (APEL) in order to draw up a coherent APEL policy. The portfolio is an important and commonly used instrument within APEL procedures. Thirty portfolios were listed within the domains of Education, Labour and Culture. A format was developed so that the different portfolios could be described in the same manner. The essential infor...

Project

Inventorying impervious surfaces in Flanders using medium and high resolution satellite data Historic

Vrije Universiteit Brussel

The goal of this research is to develop a robust method to map the spatial distribution of impervious surfaces over large areas and to characterize changes in impervious surface cover through time using remotely sensed data. The method that is developed is based on a multi-resolution approach that combines the use of medium-resolution data (type Landsat/Aster) and high-resolution data (type Ikonos/Quickbird). High-resolution data are used to map impervious surfaces in detail for a selection o...

Project

Inventory of assessments. Historic

University of Antwerp

Inventory of assessments.

Project

Inventory of recent research in Flanders in the field of social welfare, health and social care. Historic

University of Antwerp

Inventory of recent research in Flanders in the field of social welfare, health and social care.

Project

Inventory of silencio positivo. Historic

University of Antwerp

This project aims tot give a concise inventory of the most important legislative provisions of Belgian administrative law, by wich the silence of the administration after expiration of a certain term is equalled with a fictitious positive decision, the so called "silencio positivo". Some important characteristics of this fictitious decisions are briefly outlined. The various individual country reports will result in a final global report.

Project

Inverse identification of wind loads on structures

KU Leuven

For slender structures with a low eigenfrequency wind loading often constitutes the critical design load. Reliable information on dynamic wind pressures, however, is difficult to obtain. Design codes provide wind pressures for a restricted class of structures with a simple geometry. Design pressures for many critical structures have to be obtained from windtunnel tests or computational fluid dynamics (CFD). Upscaling of the experiments or adequate modelling of turbulence and boundary conditio...

Project

Inverse identification of wind loads on structures.

KU Leuven

For slender structures with a low eigenfrequency wind loading often constitutes the critical design load. Reliable information on dynamic wind pressures, however, is difficult to obtain. Design codes provide wind pressures for a restricted class of structures with a simple geometry. Design pressures for many critical structures have to be obtained from windtunnel tests or computational fluid dynamics (CFD). Upscaling of the experiments or adequate modelling of turbulence and boundary conditio...

Project

Inverse problems in Computer vision - Image Analysis & interpretation - audiovisual analysis? Historic

Vrije Universiteit Brussel

Inverse problems in Computer vision - Image Analysis & interpretation - audiovisual analysis?

Project

Inverse procedural modeling of buildings

KU Leuven

3D city modeling is a thriving area of research. Most approaches use a bottom-up strategy of some kind, i.e. first taking raw depth data with Lidar or structure-from-motion approaches, and then- possibly – trying tosimplify the data with plane fitting or the like. In the planned work, the goal is toexploit the recent successes of procedural modeling in graphics for 3D architectural design. This approach describes buildings as the result of a series of rules. The rules come from a style-specif...

Project

Inverter control in smart grids.

KU Leuven

In recente jaren is er een sterke en blijvende interesse in het gebruikvan kleine, lokale bronnen zoals, onder meer, fotovoltaïsche cellen, omde energietoelevering te ondersteunen. Bij de installatie van dergelijke bronnen wordt er gewoonlijk vanuit gegaan dat het lokale elektriciteitsnetwerk eventuele productieoverschotten kan opnemen. Echter, in de praktijk is dit niet het geval. Deel van dit probleem is op te lossen via een andere aanpak voor de invertoren welke deze energiebronnen met het...

Project

Investeringsplan Leerstoel polymeren. Recently ended

KU Leuven

This project foresees in the co-funding by the Provinciale OntwikkelingsMaatschappij (POM) of West-Vlaanderen of equipment purchases during theset-up of new research activity at KULeuven Campus Kortrijk headed by Prof. Dr. Ir. Wim Thielemans. POM supports this new activity under the Factories of the Future-New Materials initiative. Other participants in this initiative are Flanders' PlasticVision/Vlaams KunstoffenCentrum, KU Leuven Campus Brugge (Kulab) and CentexBel. Wim Thielemans' research...

Project

Investigate in voltage-gated K+ channels the operation of the electromechanical coupling mechanism. Recently ended

University of Antwerp

Voltage-gated potassium (Kv) channels are transmembrane tetramers of ¿-subunits that form K+ selective pores that actively open and shut off as response to a change in the membrane electric field. For accomplishing this each ¿-subunit contains both a voltage-sensing domain (VSD) that detects the membrane potential and an activation gate that seals off the channel pore. It is shown that the channel's VSD is formed by the S1-S4 segments whereas the channel gate localizes in the C-terminal part ...

Project

Investigating and developping the clinical use of XR, its applications and technology using the GE Innova system. Historic

University of Antwerp

Investigating and developping the clinical use of XR, its applications and technology using the GE Innova system.

Project

Investigating and punishing staff corruption at the United Nations.

KU Leuven

Corruption is a widespread and pervasive phenomenon that is a potentialdanger for every institution, even those dedicated to fight it. We assume that, due to its function, structure and international character, theUnited Nations is one of those organizations suffering from corrupt behaviour. Yet, although the UN actively promotes ‘good governance’ and ‘transparency and accountability’ in its Member States, it does not seem toapply them within its own administration. The management of its mult...

Project

Investigating carbon transport processes in plangs using the short-lived isotope 11C Recently ended

Ghent University

A collaborative research project and proposal is planned based on the short-lived isotope 11C. We will use the 11C istope to follow in vivo the internal transport of carbon in plants. A series of preliminary experiments are scheduled. Our proposal will be submitted to the US National Science Foundation. Student mentoring and seminars are also planned.

Project

Investigating psychological risk factors and testing the efficacy of an e-learning program to improve the detection and prediction of delirium in hospitalized elderly Recently ended

KU Leuven

Aspects of nursing care in the prevention and detection of delirium: psychological risk factors, screening and the use of e-learning Delirium is a common problem in the hospital with serious clinical and financial implications. Despite its high prevalence and its adverse outcomes, the syndrome remains unrecognized in 32% to 72% of the cases. Knowledge about particular aspects of nursing care, diagnostics and (treatable) risk factors, in combination with the detection of risk patients and the ...

Project

Investigating teachers' practices in using technology for Adult Language Learning (TECH4ALL) Recently ended

Universiteit Hasselt

The project aims at bringing together various experts from European countries in order to exchange ideas and practices in the area of Adult Language Learning (ALL) through new technologies. The current project seeks to take advantage of the ubiquity of the new technologies in order to support also the needs of migrant language learners. The project also intends to address issues of interculturalism by involving adult language learners of diverse cultural backgrounds in an effort to cater for...

Project

Investigating the effect of W on the solid phase reaction of nickel silicides

KU Leuven

Silicides, i.e. compounds between a metal and silicon, formed through the reaction of a metal film with a Si substrate, are often used as electrical contact layers in semiconductor devices. As device dimensions are drastically decreasing, the requirements for these silicide thin films become increasingly stringent. Currently, NiSi is used in CMOS-devices. However, the NiSi phase suffers from two degradation mechanisms at elevated temperature: (i) the formation of NiSi2, a phase with a high r...

Project

Investigating the function of Wnt/β-catenin signaling in the rhombomeric boundaries

Ghent University

The brain is a complex structure containing several cell types, organized and connected in ordered patterns. My research focuses on the formation of the hindbrain. Using frog embryos, we will be studying how two well-known developmental signaling pathways (i.e. Wnt and Notch) contribute to the organization of the hindbrain, and its transient segmentation in discrete functional units called neuromeres.

Project

Investigating the Gap Between Real and Predicted/Expected Thermal Performances of Buildings

KU Leuven

Global objective of the PhD-research is investigating the gap between predicted and real energy consumption of buildings. Main focus is on the (hygro)thermal performances of buildings components and whole buildings.So the really achieved insulation levels and airtightness will be investigated, not so much the impact of user behavior of installation performances. The research will be a combination of visual inspections, controlled laboratory and in-situ testing and numerical simulations. Three...

Project

Investigating the mechanism of action and the neuropsychological effect of neurostimulation using EEG/MEG co-recording Recently ended

Ghent University

More research to elucidate the mechanism of action of neurostimulation as a treatment for refractory epilepsy and to evaluate its effects on neuropsychological functioning is absolutely necessary. Here we wish to investigate this using simultaneous electroencephalography and magnetoencephalography recording. This projects aims optimizing stimulation parameters, identifying predictive factors and localizing new targets for future neurostimulation treatments.

Project

Investigating the role of basic carboxypeptidases.

University of Antwerp

This project represents a formal service agreement between UA and on the other hand Daiichi. UA provides Daiichi research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

Investigating the role of the dopaminergic midbrain in cognitive control and motivation in humans

Ghent University

The present project is aimed at investigating the complex role of the dopaminergic system in cognitive control, specifically at the intersection with motivation. By employing reward-modulated conflict paradigms and combining different neuroimaging techniques, functional magnetic resonance imaging and electroencephalography, we hope to illuminate the interactions between cortical and subcortical brain regions during the behavioral modulations and adjustments in human participants.

Project

Investigating the use of rainfall simulators for making flood risk maps Recently ended

Ghent University

This project aims at the optimalization of rainfall generators. The resulting time series are to be used in hydrologic models for predicting high discharges.

Project

Investigating the visual processing of biological agents: a comparison between humans and non-human primates using fMRI.

KU Leuven

Visual object recognition has a long standing tradition in monkey electrophysiology and human imaging. While most of this research has been carried out using manmade inanimate objects, one very important category ineveryday life, the human body, has been widely neglected. In the proposed project, we will not only investigate the processing of the body form as such, but also the concept of biological agents, namely the combination of body-shape and body-movement.In a set of fMRI experiments sc...

Project

Investigating Urban Design Workshops in Flanders: Researching DesignerlyResearch Recently ended

KU Leuven

Assessment and improvement of design based research methodologies by using a number of cases.

Project

Investigation and characterization of classes of buildings.

Ghent University

1. Characterizing the affine buildings of type C2, we have established a coordination system for generalized polygons. 2. Characterizing the affine buildings of type A2, we showed an unexpected connection with the projective Hjelmslev planes of levelN. 3. The last main field concerns the buildings themselves.

Project

Investigation and implementation of enhanced security management in CIPAL. Historic

University of Antwerp

Investigation and implementation of enhanced security management in CIPAL.

Project

Investigation binding proteins and metabolic proteins involved in cytokinin and cyclic nucleotide metabolism in higher plants : a proteomic approach. Historic

University of Antwerp

The project aims to analyse the variety of metabolic proteins and binding proteins involved in the cytokinin and cyclic nucleotide metabolism using proteomics. The strategies are based on an analytical sequence of high resolution protein separation, applied bioinformatics in protein analysis and mass spectrometric identification, and will be tested in two physiological models of Nicotiana tabacum.

Project

Investigation in the impact of imposed versus personal anchors on the psychometric quality of rating scales Historic

Vrije Universiteit Brussel

In human sciences in general, and more specifically in psychology, it is very common to measure constructs using all kinds of rating scales. Often little attention is paid to (the importance of) the verbal anchors that are tied to different scale scores. Recent results from our own research on the self-assessment of subjective quality of life (Bernheim, Theuns, Mazaheri, Rose, 2003), however, shows that choosing a scale with imposed scale anchors can cause important distortions of the obtaine...

Project

Investigation into the added value of mutual funds by using transactional data Recently ended

Ghent University

We use an extensive dataset of actual transactions of mutual funds to examine whether they are indeed able to beat the market by generating an excess return. We are innovative in the sense that use transactions, and therefore do not have to proxy transactions as the difference between two ensuing portfolio compositions.

Project

Investigation into the changes induced by introduction of bone marrow mesenchymal stem cell differentiated smooth muscle cell in animal model of diabetes cystophathy. Recently ended

University of Antwerp

This project represents a formal research agreement between UA and on the other hand UZA. UA provides UZA research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

Investigation into the different means and resources of foreign aid seekers in poverty. Recently ended

University of Antwerp

This project represents a formal research agreement between UA and on the other hand Provincie Antwerpen. UA provides Provincie Antwerpen research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

Investigation into the mechanism(s) of action of new strategies to treat Parkinson's disease.

Vrije Universiteit Brussel

Research for new treatment strategies in Parkinson's disease is currently oriented towards drugs that possess both antiparkinson and neuroprotective effects. Known pharmacological agents with neuroprotective properties or new molecules obtained in collaboration (IWT-SBO) via screening in vitro and in vivo willbe tested for their in vivo neuroprotective effects first in the 6-hydroxydopamine rat model, then in genetic models of Parkinson's disease. The mechanism of action via which neuroprotec...

Project

Investigation into the Use of Compliant Actuators in the Realization of hipknee- foot Orthoses

Vrije Universiteit Brussel

Research on the use of compliant actuators in the development of hip, knee and foot ortheses

Project

Investigation into the vaccination condition in intussusception during the first year of life. Historic

University of Antwerp

This project represents a formal research agreement between UA and on the other hand FAGG. UA provides FAGG research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

Investigation of a adhesion problem Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Metrotile Europe nv. The research institute TANC provides Metrotile Europe nv research results on 'Investigation of a adhesion problem' under the conditions as stipulated in the present contract.

Project

Investigation of a adhesion problem Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Cartamundi. The research institute TANC provides Cartamundi research results on 'Investigation of a adhesion problem' under the conditions as stipulated in the present contract.

Project

Investigation of a adhesion problem Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Metrotile Europe. The research institute TANC provides Metrotile research results on 'Investigation of a adhesion problem' under the conditions as stipulated in the present contract.

Project

Investigation of a black lacquer Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Heraeus Electo-Nite. The research institute TANC provides Heraeus Electro-Nite research results on 'Investigation of a black lacquer' under the conditions as stipulated in the present contract.

Project

Investigation of a broken bolt Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Chevron Philips Chemicals. The research institute TANC provides Chevron Philips Chemicals research results on 'Investigation of a broken bolt' under the conditions as stipulated in the present contract.

Project

Investigation of a defect in a dispenser Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties SBG (research institute at Hasselt University), and on the other hand, Pura. The research institute SBG provides Pura research results on 'Investigation of a defect in a dispenser' under the conditions as stipulated in the present contract.

Project

Investigation of a metal tube Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties *research insitute TANC (research institute at Hasselt University), and on the other hand, Hansen Transmissions International. The research institute TANC provides Hansen Transmissions International research results on 'Investigation of a metal tube' under the conditions as stipulated in the present contract.

Project

Investigation of an smell problem Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties IMOTANC (research institute at Hasselt University), and on the other hand, DSM R en D Solutions. The research institute IMOTANC provides DSM R en D Solutions research results on 'Investigation of an smell problem' under the conditions as stipulated in the present contract.

Project

Investigation of an smell problem in tablets Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties IMOTANC (research institute at Hasselt University), and on the other hand, DSM R en D Solutions. The research institute IMOTANC provides DSM R en D Solutions research results on 'Investigation of an smell problem in tablets' under the conditions as stipulated in the present contract.

Project

Investigation of antiageing/anti-wrinkle efficiency on the face and the forearms after oral intake of either a Si compound or a placebo product to 2 x 25 healthy caucasian female volunteers presenting actinic damaged skin at the face. Recently ended

Vrije Universiteit Brussel

-Investigation of antiageing/anti-wrinkle efficiency on the face and the forearms after oral intake of either a Si compound or a placebo product to 2 x 25 healthy caucasian female volunteers presenting actinic damaged skin at the face.

Project

Investigation of antioxidant and antiviral natural products from medicinal plants for developing a complementary therapeutical strategy against HSV- and HIV-infections. Historic

University of Antwerp

In this research antiviral and antioxidant compounds will be isolated from medicinal plants in order to develop a complementary therapeutical strategy against HSV- and HIV-infections.

Project

Investigation of a Plastisol Recently ended

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, EFTEC. The research institute TANC provides EFTEC research results on 'investigation of a Plastisol' under the conditions as stipulated in the present contract.

Project

Investigation of biodegradable polyesters for food packaging applications

Universiteit Hasselt

The current plastics industry is confronted with two major issues: on one hand the use of non-renewable fossil resources for synthesis and on the other hand the characteristic cradle-to-grave lifecycle of these materials. Biobased and biodegradable polymers however have proven to be a promising alternative for these persistent conventional plastics. In this doctoral project the focus lies on polyhydroxyalkanoates, which are produced by bacteria from renewable resources or organic waste stream...

Project

Investigation of blistering in sectional that contain polyurethane foam insulation Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Royer Expertisebureau. The research institute TANC provides Royer Expertisebureau research results on 'Investigation of blistering in sectional that contain polyurethane foam insulation' under the conditions as stipulated in the present contract.

Project

Investigation of candidate predictive bio markers for efficacy of sunitinib malate in patients with advanced oesophageal cancer, melanoma and sarcoma. Historic

Vrije Universiteit Brussel

Cancer research: Investigation of candidate predictive bio markers for efficacy of sunitinib malate in patients with advanced oesophageal cancer, melanoma and sarcoma.

Project

Investigation of clonality and virulence properties of E. faecium isolates collected during a prospective surveillance study in 8 EU countries in 2001. Historic

University of Antwerp

First, a survey in eight European countries, including 13 hospitals, of vancomycin-resistant enterococci (VRE) in at-risk hospital wards (such as the ICU and the haematology ward) was performed in 2001, and the in vitro susceptibility of ramoplanin and other drugs was tested against the isolates. A total of 1314 non-duplicate clinical enterococcal isolates were collected, and 38 (2.9%) were vancomycin-resistant: 27 E. faecium and 11 E. faecalis; 35 VanA and 3 VanB phenotypes. Rates of VRE amo...

Project

Investigation of complications of antiviral therapy with patients infected by HIV and tuberculosis. Immunological, bacteriological and clinical research. Historic

University of Antwerp

Between 10% and 40% of HIV infected patients who start highly active antiretroviral therapy (HAART) experience a syndrome characterized by an excessive inflammatory response and a paradoxical deterioration in clinical status1. This phenomenon is thought to be due to a HAART-associated recovery of pathogen-specific immune responses to pre-existing or latent infections, and has been termed immune reconstitution inflammatory syndrome (IRIS). The clinical spectrum is diverse and cases of IRIS ass...

Project

Investigation of defects in a PVC film Historic

Universiteit Hasselt

This SME-Portefeuille represents a formal service agreement between the parties IMOTANC (research institute at Hasselt University), and on the other hand, Graphityp. The research institute IMOTANC provides Graphityp research results on "Investigation of defects in a PVC film" under the conditions as stipulated in the present contract.

Project

Investigation of degradation of polycarbonate surface of a coating Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties IMOTANC (research institute at Hasselt University), and on the other hand, Sirris. The research institute IMOTANC provides Sirris research results on 'Investigation of degradation of polycarbonate surface of a coating' under the conditions as stipulated in the present contract.

Project

Investigation of delamination of a trunk Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Rieter Automotive Belgium . The research institute TANC provides Rieter Automotive Belgium research results on 'Investigation of delamination of a trunk' under the conditions as stipulated in the present contract.

Project

Investigation of different surface pre-treatments on rolled aluminium for automotive applications. Historic

Vrije Universiteit Brussel

Environmental awareness and the stricter laws endorsing this awareness, have forced the automotive industry to focus on ways to reduce the weight of the vehicles. Lighter cars mean less fuel consumption and consequently less toxic emission. Nearly all car labels are bringing out new models where some of the body-parts are aluminium instead of steel. Especially for mid-class, the 'mixed' steel/aluminium car-body will become more and more common. The use of aluminium for the body-panel...

Project

Investigation of different surface pre-treatments on rolled aluminium for automotive applications. Historic

Vrije Universiteit Brussel

Environmental awareness and the stricter laws endorsing this awareness, have forced the automotive industry to focus on ways to reduce the weight of the vehicles. Lighter cars mean less fuel consumption and consequently less toxic emission. Nearly all car labels are bringing out new models where some of the body-parts are aluminium instead of steel. Especially for mid-class, the 'mixed' steel/aluminium car-body will become more and more common. The use of aluminium for the body-panel...

Project

Investigation of dihydrobenzofuran lignans active against leishmaniasis. Historic

University of Antwerp

Based on a lead compound active against Leishmaniasis, which belongs to the class of the dihydrobenzofuran lignans, characterised in our laboratory, a more detailed investigation of the structure-activity relationship of these compounds will be carried out. Specific up-to-date methods for the synthesis of lignans, as well as QUASAR (Quantitative Structure-Activity Relationship) techniques, will be used.

Project

Investigation of epigenetic stability and safety of assisted reproduction technologies Recently ended

Vrije Universiteit Brussel

Introduction The epigenome is less stable than the genome (Bennett-Baker et al., 2003). Epimutations (i.e. modifications of the chromatin configuration or the DNA methylation pattern, resulting in altered gene expression) occur mostly in a stochastic manner and their incidence is dependent on genetic and environmental influences. Genomic imprinting is an epigenetic mechanism characterised by parent-specific marks at several chromosomal loci. The imprint marks are reset during gametogenesis a...

Project

Investigation of epigenetic suppressor and enhancer mechanisms of glucocorticoid induced therapy response in leukemia.

University of Antwerp

In this project we want to use novel and established epigenetic inhibitor/activator molecules to investigate how epigenetic enzymes modulate GC induced cell death pathways in leukemia. Secondly, we want to understand how specific GC ligands can modulate cell therapy sensitivity/response by epigenetic reprogramming of cell survival/death pathways.

Project

Investigation of fluorinated material (BP Chembel) Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, IMEC. The research institute TANC provides IMEC research results on 'Investigation of fluorinated material (BP Chembel)' under the conditions as stipulated in the present contract.

Project

Investigation of functional and structural brain abnormalities utilizing multimodal brain imaging in a neurodevelopmental animal model with relevance to schizophrenia.

University of Antwerp

The current project will follow the development of neuroinflammation together with functional brain integrity and behavioural outcome in a rodent model of maternal immune activation in vivo utilising state-of-the-art multimodal imaging biomarkers.This project will generate highly novel information about the contribution of neuroinflammation to the development of schizophrenia and its consequences for the functional integrity of the brain, and eventually provide a rationale for the implementat...

Project

Investigation of hazing at DMD's part 1 Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties IMOTANC (research institute at Hasselt University), and on the other hand, Barco nv. The research institute IMOTANC provides Barco nv research results on 'Investigation of hazing at DMD's part 1' under the conditions as stipulated in the present contract.

Project

Investigation of immune and oxidative stress aberrancies in ADHD and the potential of polyphenol-rich plant extract supplementation in ADHD therapy. Recently ended

University of Antwerp

The general aim of this project is to improve understanding of immune and oxidative stress aberrancies in ADHD and to evaluate the effects of supplementation with Pinus pinaster bark extract on behaviour and comorbid symptoms and on immune, oxidative stress and antioxidant biomarkers, as compared to placebo, no intervention and MPH treatment.

Project

Investigation of immune and oxidative stress aberrancies in ADHD and the potential of polyphenol-rich plant extract supplementation in ADHD therapy.

University of Antwerp

The general aim of this project is to improve understanding of immune and oxidative stress aberrancies in ADHD and to evaluate the effects of supplementation with Pinus pinaster bark extract on behaviour and comorbid symptoms and on immune, oxidative stress and antioxidant biomarkers, as compared to placebo, no intervention and MPH treatment.

Project

Investigation of interaction networks and mode of action applied on anti-biofilm agents

KU Leuven

Hartfalen (HF) is de belangrijkste doodsoorzaak bij mensen, boven 65 jaar, met hart- en vaatziekten. Deze aandoening wordt gekenmerkt door een progessieve, chronische afname van de contractiliteit van de hartspier. Veranderingen in cellulaire Ca2+ concentratie controleren de hartcontracties en eerder onderzoek heeft aangetoond dat HF gepaard gaat met een abnormale Ca2+ cyclus gekenmerkt door verlaagde Ca2+ affiniteit van SERCA2a. De sarco-(endo)plasmatsich reticulum Ca2+ ATPasen (P-type ATPas...

Project

Investigation of intestinal oxalate binding as a new therapy for the prevention of nephrolithiasis/nephrocalcinosis.

University of Antwerp

In the present project we will evaluate the usefulness of lanthanum carbonate in the prevention of hyperoxaluria/renal calcifications by investigating its capability to limit intestinal oxalate absorption and/or promote oxalate secretion.

Project

Investigation of In-use Stiction and Adhesion in Poly-SiGe MEMS Recently ended

KU Leuven

One of the major trends in today’s microelectronic industry is adding more and more functionality into electronic devices without compromising their size, performance and manufacturing costs. Usually, this is done by merging various components into one single chip. A very good example is the integrated miniaturized electromechanical micro devices technology, based on micro-electro-mechanical-systems (MEMS). MEMS are replacing conventional devices and can be used as actuators and sensors with ...

Project

Investigation of light interaction with brain tissue: towards full optical neuronal addressability.

KU Leuven

The detailed study of how the brain actually works requires two things:stimulation and detection of the cellular responses. Recently it becamepossible to replace electrical stimulation by optical excitation of molecules capable of transforming a light signal into an electrical stimulus, causing cell activation or inhibition. These molecules are light-sensitive ion channels (opsins) that can be introduced into specific cell types by genetic techniques, hence the term optogenetics.Theaim of thi...

Project

Investigation of new analytical methodologies for the local analysis of organic and inorganic molecules at the surface and in the subsurface of solids with a resolution at the sub-micro- and nanoscale with mass spectrometry. Historic

University of Antwerp

The aim of this project is twofold. On the one hand, the new analysis possibilities are sought via a combination of FT LMMS and D-SIMS in order to link the composition of the ultimate surface layer to the composition at small (10-50nm) or greater depth with a lateral resolution in the µm range. On the other hand, attempts will be made to change the practical limit for the lateral resolution in the analysis of the ultimate surface layer from 1 µm to 100 nm.

Project

Investigation of New Fundamental Aspects of Palladium-Catalyzed Reactions and their Practical Application in Organic Syntheses. Historic

University of Antwerp

In this research proposal two new fundamental aspects of palladium-catalyzed reactions are investigated ("base effect" and "transhalogenation") and their practical application in organic syntheses. Moreover, partly based on the knowledge of the "base effect", tandem Pd-catalyzed N arylation- and tandem Pd-catalyzed N and C arylation protocols will be developed to allow the efficient synthesis of (substituted) polycyclic azaheteroaromatic skeletons.

Project

Investigation of new methods for the direct introduction of carbon substituents on the pyridazin-3(2H)-one skeleton via organometallic chemistry. Historic

University of Antwerp

Investigation of new methods for the direct introduction of carbon substituents on the pyridazin-3(2H)-one skeleton via organometallic chemistry.

Project

Investigation of Novel Graphene-like Structures.

University of Antwerp

The main objective of my project is to reveal electronic and magnetic properties of nanosized flat materials. The subject materials of the project are graphene and graphene-like structures. Graphene is made of carbon atoms that are one of the most abundant elements in the earth crust and it was shown earlier that it has many unique properties. Moreover graphene based materials are cheap and easier to integrate to existing technological applications. The results obtained in the scope of this p...

Project

Investigation of novel targets for therapeutic intervention in chronic gut and joint inflammation in spondyloarthritides

Ghent University

In this proposal the relationship between gut and joint inflammation in spondyloarthritis is examined through investigation of the underlying cellular and molecular mechanisms with focus on biomechanical stress and hypoxia. Their role in stromal and endothelial cells will be assessed. Furthermore, the impact on the composition of the intestinal microbial flora and the host´s mucosal immune system will be explored.

Project

Investigation of novel targets for therapeutic intervention in chronic gut and joint inflammation in spondyloarthritides

Ghent University

In this proposal the relationship between gut and joint inflammation in spondyloarthritis is examined through investigation of the underlying cellular and molecular mechanisms with focus on biomechanical stress and hypoxia. Their role in stromal and endothelial cells will be assessed. Furthermore, the impact on the composition of the intestinal microbial flora and the host´s mucosal immune system will be explored.

Project

Investigation of novel targets for therapeutic intervention in chronic gut and joint inflammation in spondyloarthritides

Ghent University

In this proposal the relationship between gut and joint inflammation in spondyloarthritis is examined through investigation of the underlying cellular and molecular mechanisms with focus on biomechanical stress and hypoxia. Their role in stromal and endothelial cells will be assessed. Furthermore, the impact on the composition of the intestinal microbial flora and the host´s mucosal immune system will be explored.

Project

Investigation of nutritional and/or environmental epigenetic modulators in health and disease.

University of Antwerp

Short exposure to nutrients, toxines, endocrine disruptors, hormones, famine or stress, can have longlasting consequences by epigenetic mechanisms (chromatin code, DNA methylation, noncoding RNAs) which affect the interpretation and expression of the genetic DNA blueprint. As such chronic inflammation is epigenetically recorded in the human genome and increase incidence and progression of various diseases, including metabolic disease, autoimmune disease, cancer, neurodegeneration, cardiovas...

Project

Investigation of nutritional and/or environmental epigenetic modulators in health and disease. Recently ended

University of Antwerp

Short exposure to nutrients, toxines, endocrine disruptors, hormones, famine or stress, can have longlasting consequences by epigenetic mechanisms (chromatin code, DNA methylation, noncoding RNAs) which affect the interpretation and expression of the genetic DNA blueprint. As such chronic inflammation is epigenetically recorded in the human genome and increase incidence and progression of various diseases, including metabolic disease, autoimmune disease, cancer, neurodegeneration, cardiovas...

Project

Investigation of oncogenic cooperation and self-renewal capacity in T-cell acute lymphoblastic leukemia mouse models and implications for therapy.nbsp;

KU Leuven

generation of mouse models for T-ALL. For this purpose the TLX1 transgenic line in the group of Dr. Ferrando is used to generate mouse models in which TLX1 is combined with other oncogenes which are found together with TLX1 in human T-ALL. This work should allow studying co-operation between different T-ALL associated oncogenes.in vitro culture of primary T-ALL samples on delta-ligand expressing stroma cells and on mouse xenograft models of these primary T-ALL samples. The material generated ...

Project

Investigation of prolyl oligopeptidase as a therapeutic target for neuropathological diseases: inhibitors, substrates and ligands. Historic

University of Antwerp

The objective of this project is to investigate the interactions between P0 and relevant biomolecules, in vitro and in the cell, We envisage four lines of research: (1) the interaction with alpha-synuclein and the connection with Parkinsons disease, (2) the interaction with tubulin, intracellular transport and secretion, (3) co-localisation with other cytosolic peptidases and the connection with the aggresome, (4) comparative peptidomics of mouse brain after administration of a P0 inhibitor. ...

Project

Investigation of reliability aspects of STT-MRAM magnetic memory cells.

KU Leuven

Imec is currently developing advanced integration of p-MTJ STT-MRAM cells in scaled CMOS technology. Perpendicular magnetized p-MTJ (magnetic tunnel junction) STT-MRAM is a fast emerging non-volatile memory technology for both embedded and stand-alone applications. The spin-transfer-torque (STT) current induced switching allows for technology scaling that was not possible by the classical magnetic field induced switching. Ultimate scaling is further enabled by using the perpendicular instead ...

Project

Investigation of renal and intestinal oxalate handling: new targets for preventive therapies in the field of renal calcifications. Historic

University of Antwerp

Aim: Investigate renal and intestinal oxalate handling as new targets for preventive therapies in the field of renal calcifications. Objectives: 1. Investigate the transepithelial transport of oxalate in human renal cells. 2. Investigate the effects of intestinal oxalate binding on oxalate excretion and incidence of renal calcifications.

Project

Investigation of residual carbon / binder in MgO Recently ended

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, IMEC vzw. The research institute TANC provides IMEC vzw research results on 'Investigation of residual carbon / binder in MgO' under the conditions as stipulated in the present contract.

Project

Investigation of Self-Assembled Monolayers for Advanced Interconnects Schemes.

KU Leuven

Self-assembled monolayer is a monomolecular organic film which could spontaneously absorbed on a solid. The monomolecular is normally composed of terminal functional group (which is exposed SAM interface like methyl, phenyl, amine, carboxylic acid, alcohol....), hydrocarbon segments (which is alkyl chains tilt to minimise free volume) and head group (thiol/metals, silane, acid/metal oxide bonding to specific substrate sites). SAMs have wide applications like selective surface functionalizatio...

Project

Investigation of strongly-correlated states of photons in the presence of artificial gauge fields.

University of Antwerp

In our project we plan to investigate the interplay between the artificial gauge fields imposed on photons and the effective inter-photonic interactions with an eye to the inherenlty non-equilibrium nature of these systems. In the first place, expanding on our previous work [16,17], we will explore the possibility to excite edge-like modes in a few-particle system of photons. Obeserving the analogues of chiral edge states of the quantum Hall physics and understanding the effects of interact...

Project

Investigation of structure and dynamics of surfactant layers around carbon nanotubes by means of spin-probe and spin-label EPR methods. (FWO Vis. Fel., Jelena CULIN) Historic

University of Antwerp

The spin-probe and spin-label methods in EPR will be applied to investigate the structure and dynamics of the contact regions between carbon nanotubes (CNTs) and conjugated polymers. For this purpose, advantage will be taken from the very efficient solubilization by bile salt surfactants. The micelles formed around the CNTs will also be studied by the spin-probe method.

Project

Investigation of supramolecular nanostructures in liquid state using diffusion ordered (DOSY) NMR Recently ended

Vrije Universiteit Brussel

Nano-particles are extensively used in a broad panel of industrial applications in the fields of catalysis,2en nano-composite materials.3 Among others, their large contact surface with respect to their volume plays a crucial role in various applications. Thorough insight into the surface chemistry of such nanoparticles is accordingly of major importance, in particular also because their chemical properties can be finetuned by functionalizing their surface,4 for instance. Thus, ligands can b...

Project

Investigation of supramolecular nanostructures in liquid state using diffusion ordered (DOSY) NMR. Recently ended

KU Leuven

The large contact surface of nano-particles plays a crucial role in thebroad range of industrial applications. Therefore, the thorough insightinto the surface chemistry of such nanoparticles is of major importance. The aim of this project is to gain insight into the formation and sizeof a range of different supramolecular nano-structures such as micellesand liposomes by using diffusion NMR. The NMR is a robust and elegant technique with some important advantages when compared to other convent...

Project

Investigation of the basic aspects of an axiomatic nonlinear quantum theory and the phenomenon of nonlocality. Historic

Vrije Universiteit Brussel

This project that we propose here is relies to the ongoing FWO-project G.0372.97, entitled "Study of the effects of fluctuations on the interaction between the measuring apparatus and the system in the scope of the new experiments on individual quantum- and mesoscopic entities", initiated at the beginning of 1997 and ending at the end of 2000. Nevertheless it is not just a continuation because we want to follow the most important results of the previous project and develop them. We distinguis...

Project

Investigation of the basis aspects of an axiomatic nonlinear quantum theory and the phenomenon of nonlocality. Historic

Vrije Universiteit Brussel

We want to elaborate the generalized axiomatic approach taking into account the hypothesis DENS and the correspondences between non-locality and non-linearity. More concretely we want to concentrate on the following points: i) We want to investigate the further development of the quantum axiomatics, taking into account DENS and the failing covering law (hence non-linearity of the state space), by means of the convex set approach. Indeed, although the (non-linear) state space is no longer a co...

Project

Investigation of the construction of integrating world views

Vrije Universiteit Brussel

The research planned for the new research community 'Research on the construction of integrated worldviews' is a continuation of the research within the former research communities (1995-2000, 2000-2005, 2005-2010). The new research community still uses as a framework the five main elements of a worldview. Research is planned to deepen the understanding of each of these key elements: (1) The construction of a model of the world: research into the nature and functioning of the world (A). (2) A...

Project

Investigation of the corrosion protection of steel by means of ecological thon organic coatings. Historic

Vrije Universiteit Brussel

The goal of this work is to understand the corrosion protection of cold rolled steel by thin (thickness around 1µm) permanent (they are present during the processing and the use of the steel sheets) organic coatings (TPOC). In the first place the structure of the applied TPOC will be analysed as a function of the properties of both the steel surface and the acrylate dispersion. As such we will be able to apply TPOC with known properties. In a second step the corrosion protection aspects...

Project

Investigation of the detailed organization of the macaque visual cortex using high-resolution MRI Recently ended

KU Leuven

In primates visual information is processed in multiple areas within the cerebral cortex. Although more than 30 higher-order visual cortical areas have been identified in non-human primates, much remains to be learned about their exact boundaries, internal organization, function, and connectivity patterns. The aim of this thesis was to investigate the detailed topographic organization of extra-striate visualcortex in non-human primates using (functional) magnetic resonance imaging (fMRI). Dur...

Project

Investigation of the effect of different pharmaceutical countermeasures on the human vestibular system. Historic

University of Antwerp

In a study for NASA (NSBRI), we studied recently the effect of 4 medications against space motion sickness on the different parts of the human balance system. Building on the results of this study, the effect of specific other medications on the different parts of the human balance system will be further investigated in the proposed study. This will happen by means of investigation methods which are developed and standardized in the vestibular function lab of the University Hospital of Antwer...

Project

Investigation of the effect of nanometer technology on the evolution of integrated circuits. PartI: Devices Historic

Vrije Universiteit Brussel

The use of nanometer technology allows integrated circuits to contain devices and interconnections with dimensions below 0.1 micrometers. People believe power dissipation in devices and interconnect lines will prevent a further down scaling of IC technology below this 0.1 micrometer linewidth. In nthis project we want to investigate whether, by using nanometer technology, transistor structuresand opto-electronic devices can be realized that can bring IC technology beyond this limit. By studyi...

Project

Investigation of the effect of temperature controlled microwave flash heating on the reaction rate of palladium catalyzed reactions with chlorinated azaheteroaromatic substrates. Historic

University of Antwerp

Investigation of the effect of temperature controlled microwave flash heating on the reaction rate of palladium catalyzed reactions with chlorinated azaheteroaromatic substrates.

Project

Investigation of the effect of TGF-b1 and TAM67, a transdominant mutant of c-jun on the growth of ovarian cancer cells in vitro and in vivo, with the use of recombinant viral constructs derived from Adeno-Associated Virus and Adenovirus. Historic

Vrije Universiteit Brussel

TGF-B1 belongs to a superfamily of several tens of growth factors, which perform a broad spectrum of biological functions. in many cell types TGF-b1 is secreted as a polypeptide which needs to undergo extracellular activation. The activated from of TGF-b1 binds to specific receptors and has a growth suppressive effect on several cell types. Details about the signal transduction pathway are omited here because of lack of space. Important is that some cell types which are sensitive to growth i...

Project

Investigation of the effects of lanthanum carbonate on vascular calcification in a rat model of chronic renal failure. Historic

University of Antwerp

Investigation of the effects of lanthanum carbonate on vascular calcification in a rat model of chronic renal failure.

Project

Investigation of the genetic basis and the pathogenic mechanisms involved in bicuspid aortic valve associated thoracic aortic aneurysm.

University of Antwerp

Bicuspid aortic valve is the most common congenital heart defect and is often associated with ascending aortic aneurysms. As such it presents an important health problem. The inheritance pattern is most consistent with an autosomal dominant disorder with variable penetrance and expressivity. Within this project, we will identify the genetic basis using copy number variation analysis and whole exome sequencing and we will investigate the potential contribution of TGFβ signaling cascades.

Project

Investigation of the glucose sensor in pancreatic a- and b-cells. Historic

Vrije Universiteit Brussel

Insulin-producing b-cells and glucagon-producing a-cells play a central role in glucose homeostasis (1). These cells are directly and inversely regulated by D-glucose, by mechanisms involving uptake and metabolism of the sugart. Our laboratory studies the molecular and cellular biology of pancreatic glucose sensing. Previous results have contributed to the hypothesis that the expression level of glucokinase in a- en b- cells determines (in part) the functioning of the sensor (2-4), both in ra...

Project

Investigation of the impact of ionizing radiation on the physico-chemical properties of microparticles in view of non-invasive dosimetry

KU Leuven

The intended doctoral research is part of a research and development plan of a new non-invasive dosimeter for support of radiotherapy. The new dosimeter will measure local radiation effects with the help of microparticles. It has been found that the properties of microparticles change significantly when exposed to ionizing radiation at clinically used dose levels. A series of diverse but complementary experimental techniques will be employed to investigate the physico-chemical, structural and...

Project

Investigation of the "in vivo" interaction of melphalan with DNA with miniaturized liquid chromatography coupled to electrospray tandem mass spectrometry. Historic

University of Antwerp

Chemotherapeutic compounds used in the treatment of cancer reduce tumoral cell growth by interacting with different biomolecules. As such they disturb or block cell replication. One of these compounds, melphalan (L-phenylalanine mustard, 4-(bis(2-chloroethyl)amino)-L-phenylalanine, is a bifunctional alkylating agent that covalently binds to the nucleophilic sites present in DNA. In this study the interaction of melphalan is studied with DNA in 'in vivo' experiments. Furhtermore the inter...

Project

Investigation of the in vivo role of parkin by manipulation of parkin expression in rodent models of Parkinson's disease Recently ended

KU Leuven

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder. It is neuropathologically characterized by a progressive degeneration of dopaminergic neurons in the substantia nigra (SN) and the presence of intracellular alfa-synuclein (alfa-SYN) containing inclusions called Lewy bodies. Although the etiology of PD is still incompletely understood, the discovery of genes linked to familial PD has tremendously improved our knowledge on the molecular mechanisms involved in the ...

Project

Investigation of the mechanism of action of new therapies for Parkinson's disease Historic

Vrije Universiteit Brussel

In this project we want to study 2 aspects of the new treatment strategies for Parkinson's disease. Since drug research is focused on developing new drugs with both neuroprotective and antiparkinsonian activity, we want to screen some possible candidate molecules with this profile. First, we will study the neuroprotective effect of these drugs in parkinsonian rats. If they turn out to be neuroprotective, we want to investigate through which mechanism this occurs. In a second part of this proj...

Project

Investigation of the mechanisms leading to interphase and intergranularresidual stresses in multiphase alloys and their impact on the materialproperties.

KU Leuven

A metallic alloy consists of different grains and phases. These different grains and phases will have different mechanical properties. When thematerial is deformed, this will result in residual stresses in the material. These are stresses that remain after unloading.The main difference between the grains is their orientation with respect to the sample (i.e. crystallography). For the different phases the morphology of the hard second phase particles will play an important role.Little attention...

Project

Investigation of the neuroprotective effect of hypothermia in combination with multifunctional drugs in the endothelin-1 rat model for transient focal cerebral ischemia. Historic

Vrije Universiteit Brussel

CVA is defined ass a loss of brain functions by a disturbance in cerebral perfusion. CVA is worldwide one the most important causes of mortality and morbidity. Furthermore, due the higher life expectations of the population, CVA will become a bigger socio-economic burden for health care.

Project

Investigation of the pharmacologicak abd physiological distinction af AT1 receptor antagonists. Historic

Vrije Universiteit Brussel

Angiotensin II is the major peptide of the renin-angiotensin system RAS and plays a crucial role in the cardiovascular homeostasis. Dysfunction of the RAS can lead to hypertension. Recently, non-peptide AT1 antagonists have been developed and they have an antihypertensice effect. Pharmacological tests with these antagonists showed their insurmountable inhibition, i.e. they did not only produced a rightward shift of the angiotensin II induced dose-response curve, but they also lowered the maxi...

Project

Investigation of the PhoPQ system and nucleotide biosynthesis as targets for inhibition of Salmonella Typhimurium biofilm formation.

KU Leuven

Important human pathogens become (multi-)resistant to currently availabe antibiotics, urging the need for alternative anti-bacterical treatments. Biofilms are surface-associated communities of bacteria, embedded in a self-produced slime layer. The importance of biofilms becomes clear from the fact that they are involved in 80% of all infections and occur widespread in the environment. Bacteria in biofilms are up to 1000-fold more resistant to antibiotics, disinfectants and host immune systems...

Project

Investigation of the possibilities of a new X-ray fluorescence instrument equipped with high-energetic polarized excitation for applications to precious metals. Historic

University of Antwerp

Umicore Precious Metals Refining (UPMR) in Hoboken takes in different sorts of material for the production of precious metals. The different resources need to be analysed very accurately. During the production process, control analyses are also necessary. Not all the resources demand the same pre-concentration process, hence the final analysis specimens occur in different matrices. Every type of resource has its own typical matrix and concentration range. For each resource a typical analysis ...

Project

Investigation of the presence of additives in phenolic foam obtained from a waste Recently ended

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Sumitomo Bakelite Europe. The research institute TANC provides Sumitomo Bakelite Europe research results on 'Investigation of the presence of additives in phenolic foam obtained from a waste' under the conditions as stipulated in the present contract.

Project

Investigation of the pyrolysis process - part 1 Recently ended

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Thermo-clean nv. The research institute TANC provides Thermo-clean nv research results on 'Investigation of the pyrolysis process - part 1' under the conditions as stipulated in the present contract.

Project

Investigation of the relation between optical and morphological properties of aluminium surfaces for the production of mirror finish materials. Historic

Vrije Universiteit Brussel

This project is situated in the field of continuous surface treatment of rolled aluminium. The treated surfaces are used for the application of light reflectors. The purpose of the study is to find the correlation between optical reflection and the morphology of the created surfaces. In addition it is tried to quentify the optical and morphological properties of the aluminium surface. The last point in this investigation is to obtain the relation between a et of batch send continuous ...

Project

Investigation of the relationship between falling and equilibrium and posture in stroke patients. Historic

University of Antwerp

The development en validation of head and bodypositioning technology in strokepatients. The relationship between this posture and falling is investigated. In particular processes of equilibrium and neuropsychology are studied. Acquired knowledge is implemented in therapy and is subsequently evaluated.

Project

Investigation of the role of dopamine D4 receptor modulation on µ-opioid receptor signaling Recently ended

Ghent University

The dopamine D4 receptor and the µ-opioid receptor are G protein-coupled receptors. We will investigate the cross-talk between both receptors.

Project

Investigation of the role of Sip1 in BMP-controlled aldult neurogenesisin the mouse central nervous system in baseline conditions and upon stroke.

KU Leuven

Sip1, a Smad-interacting and DNA-binding transcription factor, is a multidomain protein of which the role and action mechanisms in the developing embryo and embryonic stem cell niches are currently investigated in our lab. In this project we aim to extend our investigation of Sip1 in the mouse from embryonic to adult stem cell niches. More specifically we're going to look at the subventricular zone lining the lateral ventriclesof the adult mouse brain, where Sip1 is present and possibly influ...

Project

Investigation of traffic flows from, to and within the Antwerp port area. Historic

University of Antwerp

This project will lead to an overview of traffic flows from, to and within the port of Antwerp, taking into account: - commuter traffic; - freight transport; - the flows between the left bank and the right bank.

Project

Investigation of uretral sensation.

University of Antwerp

This project represents a formal research agreement between UA and on the other hand UZA. UA provides UZA research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

Investigation of uretral sensation.

University of Antwerp

This project represents a formal research agreement between UA and on the other hand UZA. UA provides UZA research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

investigation on the consistency, incidence and evolution of upper limb oedema on patients after mastectomy. Historic

Vrije Universiteit Brussel

to prevent dissemination after mastectomy, axillar ganglion resection is peformed. Besides complications like scar pain, paresthesia and loss of mobility, secondary lymph oedema occurs in 22-34% of the cases. Some authors already described the positive influence of specific physiotherapy treatment, like manual lymphatic drainage,pressotherpie and elastic stocking, on patients after mastectomy. To investigate this phenomenon on clinical and fundamental bases, we will screen patients by means o...

Project

Investigation on the isolation and identification of proteins involved in the cytokinin and cyclic nucleotide signalling metabolism using proteome technology. Historic

University of Antwerp

Investigation on the isolation and identification of proteins involved in the cytokinin and cyclic nucleotide signalling metabolism using proteome technology.

Project

Investigation on the method for multipoint optimization of turbomachinery Historic

Vrije Universiteit Brussel

Joint PhD agreement for Wang Xiaodong

Project

Investigation peace: a political-theoretical study of the role of education and power in establishing peace. Case-study: Europe after 1945. Historic

University of Antwerp

This project seeks to elucidate the meaning of peace. It is hypothesised that education and power are central concepts and practices for understanding the establishment and consolidation of peace. Support for this claim will be sought at three levels: political theory, international relations theory, and history. European peace and security will be our case-study.

Project

Investigations of musculoskeletal disorders in health-related occupations Historic

Vrije Universiteit Brussel

Investigations of musculoskeletal disorders in health-related occupations

Project

Investigations on the active metabolites of promising natural products.

University of Antwerp

This project comprises the identification of the active metabolites of selected natural products with a proven biological activity. The focus will be on Cranberry (Vaccinium macrocarpon) which is used against urinary tract infections, and the Congolese medicinal plant Nauclea pobeguinii, which showed promising activity against malaria in vitro as well as in vivo. For both plants, in vivo activity may be attributed to the formation of biologically active metabolites. The identification of thes...

Project

Investigation the structure an the "gatting" mechanism of the cytoplasmic activation gate in voltage-dependent K+ channels. Historic

University of Antwerp

Voltage-gated K+ channels compose four individual ¿-subunits that surround an ion conducting pathway. Each ¿-subunit contains 6 transmembrane segments (S1-S6) with a pore loop (P-loop) between S5 and S6. The positively charged S4 segment forms with the contribution of S2 and S3 the channel's spanningssensor. The cytoplasmic activation gate that opens or closes the channel pore is located in the C-terminal part of S6. A change in membrane potential results in a conformational change of S4 (spa...

Project

investigation the value of shopping path data for marketing intelligence

Ghent University

This proposal is about tracking the movements of customers 'i.e. paths) in a shop environment such as shopping-malls. Path data contains valuable information for marketind researchers because it describes how consumers interact with their environment. The aim of this project is to develop methods for descriptive as well as more advanced analyses to generate managerial insight for this new data source.

Project

Investigation to avoid cold and heat stress in animals kept on pasture (PASTRESS).

KU Leuven

There is a growing concern for the welfare of animals kept on pasture. This project will apply epidemiological and experimental research in order to know if cattle and horses need protection under belgian weather conditions, and how that protection should be implemented. Guidelines willbe formulated for keepers, inspectors, animal rights organizations and the broader public.

Project

Investigator-Initiated Research Agreement

Universiteit Hasselt

Hasselt University is investigating "Uptake of Hepatitis C treatment in drug users with chronic hepatitis C in a substitution program: the LINK study". The study is led by Professor dr. Geert Robaeys, associated with the Biomed Hasselt University research institute. The basis for this study is data from surveys which are collected in substitution centers, based on a protocol approved by the Ethics Committee.

Project

Investing in useful knowledge in the Antwerp diamond sector, from the second half of the sixteenth century to the end of the ancien régime Recently ended

University of Antwerp

In this project investing in useful knowledge is examined for the Antwerp diamond sector in the early modern period. Central questions are 1) how learning on the shop floor transformed as a result of the changes in the production structures and product innovations, 2) which role investments in skills played in the development of this skill-intensive sector and 3) which role institutions played in contracting those investments.

Project

Investment returns and risk premia for Belgian corporate bonds (1832-2010) Recently ended

University of Antwerp

The Brussels stock exchange was one of the top ten most important stock exchanges in the world in the 19th and early 20th centuries. Companies from all sectors (railways, coal mines, zinc companies, metal, glass, banks, electricity companies etc.) were listed on it. Moreover, the Brussels Stock Exchange was very internationally oriented before the First World War with many shares, government bonds and corporate bonds from goverments and companies all over the world (or Belgian companies opera...

Project

Investment Returns in the Long Run: Evidence from Belgium 1838-2010. Recently ended

University of Antwerp

We investigate long run investment returns for stocks, government bonds and cash. Our analysis is based on a (worldwide) unique database which covers all securities ever listed on the Brussels Exchange / Euronext Brussels in the period 1838-2010. We construct new, value weighted return indices for government bonds and analyze the equity risk premium and term premium.

Project

Invigorating scientific and social aspects of film and image culture in Antwerp and Flanders. Historic

University of Antwerp

This project aims to continue and further develop the current 'Film and Image Culture in Antwerp and Flanders' project (PA-UA 2003-2005) which was set up to stimulate academic education and research in this domain and to invigorate ways of cooperation among different scientific, cultural and artistic institutions in the area. The core activity comprises conducting and further developing the highly successful Master Program in Film Studies and Image Culture, which is to date a unique offering ...

Project

In Vitro 3D Intra Articular Motion Analysis With Contact Areal Displacement Evaluation : Methodological Development With Application on the Elbow Joint. Historic

Vrije Universiteit Brussel

The intra articular motion survey is twofold : a) methodology : to obtain the best possible result we should analyse the articular motion in vivo (3D CAD modeling based on medical frameprocessing). Despite its accuracy and value it still lengthy and should be further refined by means of surface mapping. b) Applied examination on the elbow joint

Project

In vitro and in vivo analysis of the mode of action of a new Pseudomonas aeruginosa antipersister molecule

KU Leuven

The opportunistic, gram-negative pathogen Pseudomonas aeruginosa is responsible for about 10% of the nosocomial infections in Belgium and is very hard to threat with the existing therapies. An important reason for this is the presence of a small population of cells that are highly tolerant to killing by antibiotics, the so called persister cells. Persister cells are responsible for the recalcitrant nature of chronic infections, they attribute to the antibiotic tolerance of biofilms and can, b...

Project

In vitro and in vivo characterization of the molecular mode of action of selected peroxisome proliferators in zebrafish (Danio rerio). Historic

University of Antwerp

Peroxisome proliferators (PPs) can interfere with important nuclear hormone receptors (PPARs). Dispite the crucial role of these receptors in fundamental biological processes, very little information is available on the possible adverse effects of PPs and interference with PPAR-mediated pathways in teleosts. With the proposed research we aim to unravel the PPAR-pathways (in vitro as well as in vivo) to enable environmental risk evaluation of PPs.

Project

In vitro and in vivo investigations of metabolisation by gut flora, absorption, and antioxidative activity of polyphenolic constituents of human food. Historic

University of Antwerp

The first objective of this research project is to determine the in vivo antioxidant profile of plant polyphenols after oral supplementation in animals of some selected standardised plant preparations. However, prior to starting this in vivo evaluation, it is essential to extend the existing battery of assays of the research group with additional methods for the assessment of oxidative damage to other endogenous biomolecules than lipids, such as DNA and proteins. The second objective is the d...

Project

In vitro and in vivo markers of beta cell death and function. Historic

Vrije Universiteit Brussel

AIMS: 1) To develop sensitive and specific extracellular markers of beta cell death and functional beta cell mass that can be applied for in vitro quality assessment and standardization of therapeutic beta cell grafts. 2) To investigate the applicability of these markers for the detection and quantification of beta cell death in vivo prior to development or recurrence of hyperglycemia in animal models of beta cell damage and transplantation. 3) To investigate the applicability of these mar...

Project

In vitro and in vivo studies on the role of the IRAP enzyme/AT4 receptor system in learning and memory processes Historic

Vrije Universiteit Brussel

INTRODUCTION Ang IV and the IRAP enzyme /AT4 receptor system The renin-angiotensin system (RAS) is widely recognised as the most powerful signalling system for controlling sodium balance, body fluid volumes and arterial blood pressure. The major RAS peptide is the octapeptide angiotensin II (Ang II). It is formed by enzymatic processing of Ang I by the angiotensin-converting enzyme (ACE) present in plasma as well as in tissues such as brain, kidney and heart. Although Ang II has long been...

Project

In vitro and in vivo studies to assess the phosphate binding capacity of a noval, urease-based phosphate binder Historic

University of Antwerp

The current project aims to evaluate the in vitro and in vivo phosphate binding capacity of a new urease-based phosphate binder. The formulation of this novel phosphate binder yielding optimal phosphate binding capacity, the pH dependency and the relative potency of its phosphate binding capacity will be studied in vitro, whereas administration of the urease-based phosphate binders to rats will be used to assess its in vivo phosphate binding capacity

Project

In vitro and in vivo study into the mechanisms of vascular calcification in chronic renal failure. Historic

University of Antwerp

In vitro and in vivo study into the mechanisms of vascular calcification in chronic renal failure.

Project

In vitro and in vivo study into the mechanisms of vascular calcification in chronic renal failure. Historic

University of Antwerp

In vitro and in vivo study into the mechanisms of vascular calcification in chronic renal failure.

Project

In vitro and in vivo study of mono- and polymicrobial biofilms as a major cause of therapeutic failure in intensive care units (ICU). Recently ended

University of Antwerp

Biofilm-related infections prove exceedingly difficult to treat because the organisms in a biofilm are protected from the circulating antimicrobials. Up till now, there have been relatively few studies investigating biofilm development in clinical isolates. Current in vitro methods for studying microbial adhesion and growth on biomaterial surfaces lack the influence of the host immune system, endorsing the specific need for animal models that allow temporal and spatial measurements based on n...

Project

In vitro and in vivo study of the transdermal delivery by iontophoresis of vasodilatory and anti-inflammatory physiotherapeutical drugs by means of analytic and noninvasive bio-engineering methods. Historic

Vrije Universiteit Brussel

Iontophoresis is a technique which involves the transport of charged molecules into a tissue using an electric current and the appropriate electrode polarity. This technique is almost solely put into practice by physiotherapists, and although it has been used for several decades, there is a great lack of fundamental studies in the efficiency of percutaneous penetration by iontophoresis of drugs. The purpose of the in vitro part of our study is to determine the influence of both the electrical...

Project

In vitro bio availability study. Historic

University of Antwerp

This project represents a formal service agreement between the parties Universiteit Antwerpen and Lodewijckx NV. UAntwerpen provides Lodewijckx NV research results on "In vitro biobeschikbaarheidsstudie" under the conditions as stipulated in the present contract.

Project

In vitro cell-free protein synthesis and purification platform.

Vrije Universiteit Brussel

The LMCT is involved in immunotherapy with autologous dendritic cells electroporated with mRNA encoding tumor antigens. A platform for the in vitro synthesis of mRNA has been established. A major effort is the detection of immunologic biomarkers associated with clinical response after immune therapy. So far, most of the efforts are focused on the detection of a cellular response (1-3). The immunosuppressive environment of the tumor does not support cross-priming, which is necessary for tumor...

Project

In vitro degradation of Mg-alloys under physiological conditions

KU Leuven

The MagnIM is the highly interdisciplinary European network (material scientists, physicists, biologists, (bio)chemists, surface chemists and medical doctors) of eight partners from six countries which aims at the development of a tailored biodegradable magnesium based implant materials.In addition to their biocompatibility another important property ofthe new magnesium alloys to be developed in MagnIM will be their degradation rate in the body. This degradation rate needs to be matched again...

Project

In vitro differentiation of bone marrow stem cells to hepatocytes: characterization of the biotransformation capacity, regulation by 'liver-enriched' transcription factors and influences of Trichostatin A. Historic

Vrije Universiteit Brussel

Isolated primary hepatocytes and their cultures are important in vitro models for pharmaco-toxicological research of xenobiotics. Freshly isolated cells and their short-term cultures (2 to 3 days) can be used to reveal the major pathways of biotransformation of new molecules along with the enzymes involved, the metabolites and their intermediates formed. To examine long-term effects, like induction, long-term cultures are needed (at least 2 weeks). A problem, however, is that hepatocytes in c...

Project

In-vitro differentiation of human embryonic stem cells into primordial germ cells and male gametes Historic

Vrije Universiteit Brussel

Fertility has become an important issue in the concept of quality of life. At this moment, male patients faced with infertility due to the loss of spermatogonial stem cells can only be offered cryobanking of semen as a strategy to preserve their fertility. Even though semen banking is an easy and effective technique, there remains a significant group of patients (e.g. prepubertal cancer patients, Klinefelter's patients,...) who cannot benefit from this strategy and currently, have no option t...

Project

In vitro DNA repair phenotype: development, comparison and validation Historic

Vrije Universiteit Brussel

The individual susceptibility for mutagens/carcinogens is determined by genetic polymorphisms of the genes involved in the expression of a DNA lesion into a mutation: metabolism, DNA repair, cell cycle control and apoptosis/necrosis. Since several genes define a given pathway, it is difficult to directly predict the global effect starting from the genotype of each gene. For these reasons, it is important to assess integrated phenotypes. With this project we aim, in association with other par...

Project

In vitro effect of diabetes farmaca on beta cell proliferation Historic

Vrije Universiteit Brussel

In vitro effect of diabetes farmaca on beta cell proliferation

Project

In vitro evaluation of compounds for cytotoxicity and selectivity in a series of test models Historic

University of Antwerp

This 'contract research' specifically evaluates chemical compounds that are part of a pharmacological optimisation programme on a broad panel of cells, bacteria, yeast, fungi and protozoan parasites in order to obtain a more detailed insight into the pharmaclogical activity.

Project

In vitro evaluation of the role of hepatic uptake transporters (OATP family) in the disposition of HIV protease inhibitors.

KU Leuven

Sandwich-cultutred hepatocytes isolated from rat, dog, pig and human liver tissue are being used to evaluate the interaction of HIV protease inhibitors with functionality of uptake transporters of the OATP family (Organic Anion Transporting Polypeptide) in the liver. This information is relevant in light of predicting and understanding clinically relevant drug interactions with protease inhibitors. Recent data obtained inour group ((URL:http://dmd.aspetjournals.org/cgi/content/abstract/36/7/1...

Project

In vitro experiments to determine the effects of compounds on T-cell proliferation and cytokine production. Historic

Universiteit Hasselt

Barrier Therapeutics is a pharmaceutical company focused on the development and commercialization of medicines in the field of dermatology. In the past BIOMED already did some contract research for Barrier Therapeutics. The present agreement for contract research includes the implementation of in vitro experiments and is part of the validation of immunological effects (T-cell proliferation and cytokine production) of an existing anti-histaminicum.

Project

In vitro generation of AML specific T cells from gematopoietic stem cells and functional characterization of these cells in an in vivo animal model Recently ended

Ghent University

Hematopoietic stem cells will be transduced to express a T Cell Receptor. This receptor will be optained by immunizing against WT1 tumor antigen. The T cell receptor genes will be cloned from WT1 speciific T cells and subsequently used for transduction of the stem cells. Stem cells will be differentiated in vitro to T cells and functionality will be assayed in an in vivo animal model.

Project

In vitro interaction between chemo- and radiotherapy under hypoxic conditions. Historic

University of Antwerp

Because of promising results in the clinic and enormous interest for in vitro research to the combination of chemo- and radiotherapy, an efficient in vitro hypoxia model will be developed to study the interactions between chemo- and radiotherapy under hypoxic conditions. This model will be used to investigate the interaction both under normoxic and hypoxic conditions and to study possible factors of the radiosensitizing mechanism.

Project

In vitro interaction between chemo- and radiotherapy under hypoxic conditions. Historic

University of Antwerp

It is well established that solid tumours frequently contain regions of hypoxia. Tumour hypoxia may induce resistance or a reduced sensitivity to radiation and chemotherapy. In that respect, it is very important to investigate new therapies in preclinical research under hypoxic conditions. However, an efficient in vitro hypoxia model is not available so far. Therefore, it seems very desirable to develop and optimize an hypoxic model. In this way, it will be possible to study the interaction b...

Project

In vitro interaction between chemo- and radiotherapy under hypoxic conditions. Historic

University of Antwerp

It is well established that solid tumours frequently contain regions of hypoxia. Tumour hypoxia may induce resistance or a reduced sensitivity to radiation and chemotherapy. In that respect, it is very important to investigate new therapies in preclinical research under hypoxic conditions. However, an efficient in vitro hypoxia model is not available so far. Therefore, it seems very desirable to develop and optimize an hypoxic model. In this way, it will be possible to study the interaction b...

Project

In vitro interaction between chemo- and radiotherapy under hypoxic conditions. Historic

University of Antwerp

It is well established that solid tumours frequently contain regions of hypoxia. Tumour hypoxia may induce resistance or a reduced sensitivity to radiation and chemotherapy. In that respect, it is very important to investigate new therapies in preclinical research under hypoxic conditions. However, an efficient in vitro hypoxia model is not available so far. Therefore, it seems very desirable to develop and optimize an hypoxic model. In this way, it will be possible to study the interaction b...

Project

In vitro interaction between chemotherapy and radiotherapy in hypocisic conditions. Recently ended

University of Antwerp

This project represents research between the UA and a private institution. UA provides the private institution the research results named in the title of the project.

Project

In vitro interaction between chemotherapy and radiotherapy under hypoxic conditions. Historic

University of Antwerp

In vitro interaction between chemotherapy and radiotherapy under hypoxic conditions.

Project

In vitro interaction between chemotheray and radiotherapy under hypoxic conditions. Historic

University of Antwerp

This is a fundamental research project financed by the Research Foundation - Flanders (FWO). The project was subsidized after selection by the FWO-expert panel.

Project

In vitro investigation of neuronal polarization and growth in a microstructured environment Recently ended

KU Leuven

To ultimately restore function to damaged nerves after injuries or diseases, we need to understand better how neurons respond to changes in their immediate surroundings. This micro-environment comprises cues of different nature; biophysical elements like micro-topographies and electrical events, but also surface-bound and soluble chemical gradients. Studying aspects of the microenvironment separately and in concert in a well-controlled in vitro situation allows to gain valuable insight on the...

Project

In-vitro investigation of variations of the auriclar surface of the sacrum and innominate bone Historic

Vrije Universiteit Brussel

With an in-vitro investigation of spatial details of the variations of the auricular surface of the sacrum and innominate bone, a contribution will be made to the understanding of function and dysfunction of the sacro-iliac joints (SIG). The SIG is a particular point of interest with regard to low back problems and it is often treated with manual therapy techniques. The actual classification of anatomical joints serves as a basis for a work hypothesis, in which a parallel configuration of a s...

Project

In-vitro maturation and cryopreservation of human ovarian tissue Historic

Vrije Universiteit Brussel

The objectives of this research project were to work out an optimal protocol for cryopreservation of small cortical pieces and isolated follicles from human ovaries and to define suitable culture conditions for primordial and primary ovarian follicles. Ovarian cortical slices were cryopreserved using protocols from literature. After thawing, the survival rate was estimated by histological morphometry using light microscopy and electron microscopy: oocyte-granulosa-cell contacts and oocytes' ...

Project

In vitro maturation of equine oocytes: nuclear versus cytoplasmic maturation.

Ghent University

The nuclear and cytoplasmic maturation of equine oocytes during in vitro culture will be evaluated in order to determine the efficiency of a novel oocyte maturation medium using in vitro and in vivo parameters as end points. Maturation will be assessed in vitro using confocal microscopy after staining of celorgannelles and in vivo based on blastocyst development.

Project

In vitro maturation of oocytes from antral follicles in humans. Historic

Vrije Universiteit Brussel

IVF treatments are always preceeded by an ovarian superovulation with gonadotropins. This hormonal stimulation ends in severe life-threatening complications in 1-3 % of all patients and 30 % of superovulated women declare to experience serious side effects. This research project aims to circumvent ovarian stimulation by retrieval of immature oocytes from small antral follicles. Therefore the oocyte retrieval technique has to be adapted and alternative culture systems have to be developed. ...

Project

In vitro modulation of dendritic cells for immunotherapy of atherosclerosis. Historic

University of Antwerp

The present researchproject evaluates the potential for therapeutic immunomodulation of atherosclerosis using dendritic cells and antigen-specific vaccinationtherapy toward autoantigens implicated in the pathogenesis of atherosclerosis, starting with the heat shock protein 60 autoantigen.

Project

In vitro PBDE's metabolism by pet-animals liver microsomes – evaluation of their potential on assessing human exposure to indoor contaminants. Recently ended

University of Antwerp

The proposed research project aims on characterizing the in vitro metabolism of selected indoor contaminants, like polybrominated diphenyl ethers (PBDEs) and identifying their hydroxylated metabolites formed. Since the use of pet animals as sentinels to monitor the contamination degree of indoor environment was already suggested as a good alternative to human biomonitoring (especially when addressing toddler's exposure), investigation of the in vitro metabolism will be performed on cat liver ...

Project

In vitro physiological and functional morphologic study of neurotransmitter receptors related to pulmonary neuroepithelial bodies. Historic

University of Antwerp

The project should allow us to investigate the presence of neurotransmitter receptors on pulmonary neuroepithelial bodies and their complex selective innervation. Among other methods, we will use our recently developed in vitro lung slice model, which allows the microscopic visualisation of ph~siological parameters by means of the confocal UltraVIEW Live Cell Imager. We plan to concentrate on the neurotransmitters that we previously demonstrated to be present in the system.

Project

In vitro research on the interaction between chemotherapy and radiotherapy under hypoxic conditions, in view of an improved treatment in cancer Historic

University of Antwerp

Because of promising results in the clinic and a vast interest for in vitro research to the combination of chemotherapy and radiotherapy, an efficient in vitro hypoxia model will be developed to study the interactions between chemotherapy and radiotherapy under hypoxic conditions. This model will be used to investigate the interaction both under normoxic and hypoxic conditions and to study possible regulating factors and signal transduction of the radiosensitizing mechanism.

Project

In vitro research on the intracellular pathways of radiosensitisation using hypoxic and normoxic conditions in view of an improved treatment of cancer. Historic

University of Antwerp

The aim of the project is 1) Research on different signal transduction pathways to clarify the mechanism of radiosensitisation under normoxic and hypoxic conditions, and to elucidate the mechanism of resistance under hypoxia; 2) In depth study of the involvement of proteins with altered gene expression using western blot analysis and flow cytometry.

Project

In vitro research on the molecular mechanisms of radiosensitisation and of radio- and chemotherapy resistance, under hypoxic conditions. Recently ended

University of Antwerp

Hypoxia is an important factor for the effectiveness of chemo- and radiotherapy. Different factors that could be of key importance for the radiosensitising effect, i.e. cell cycle, apoptosis, p53, HIF-1 will be investigated under hypoxia. Secondly, signal transduction pathways will be investigated to determine the mechanism of radiosensitisation and the mechanism of chemo- or radiotherapy resistance during hypoxia.

Project

In vitro research to the interaction between chemotherapy and radiotherapy. Historic

University of Antwerp

There is an urgent need for preclinical research to the interaction between chemo- and radiotherapy, to optimise the clinical application. Gemcitabine is a nucleoside analogue with radiosensitising properties. In this project, the molecular mechanism of this enhancement effect will be investigated. The radiosensitising effect is correlated with the cell cycle effect of gemcitabine. Therefore, the checkpoint mechanism will be studied to determine its responsibility for the enhancement effect. ...

Project

In vitro research to the intracellular pathways of radiosensitisation considering its application with chemotherapy and radiotherapy. Historic

University of Antwerp

Objectives of the project: 1. To study of the influence af gemcitabine and/or radiotherapy on the cell cycle checkpoint-mechanism ta understand the molecular mechanism af cell cycle arrest. 2. To clarify the apoptotic pathway: Is the increased apoptosis observed after treatment with gemcitabine/radiotherapy reached by the mitochondria' ar by the receptor-mediated pathway? 3. To Investigate the influence af gemcitabine on the repair af radiation-induced DNA damage as a possible mechanism fo...

Project

In vitro simulation of the interactions between a lactic acid bacterium starter culture and Listeria in a fermented sausage environment Historic

Vrije Universiteit Brussel

This project aims at investigating the bacterial population dynamics in fermented sausage, by simulating the sausage fermentation proces in vitro, using a meat simulation medium and streering of process technological factors (pH profile to simulate buffering by meat, temperature control, on-line salt addition to simulate drying process, ...). This simulation will be used to study the growth of undesirable bacteria during meat fermentation, the impact of bacteriocin production by LAB starter c...

Project

In vitro study into the renal transport of possible nephrotoxic molecules by means of primary human kidney cell cultures. Historic

University of Antwerp

This project deals with the study of primary, tubular human kidney cell cultures as a possible in vitro model of renal molecule transport. At first instance we are interested in the transport of molecules that are possibly nephrotoxic (for example drugs which are in most cases orgnanic anions or kations) because of their transport by the kidney.

Project

In vitro study of the apoptotic signal transduction pathway necessary for radiosensitisation. Historic

University of Antwerp

The combination of chemo- and radiotherapy is a promising treatment of cancer. This combination results often in an increase of apoptotic cell death. The molecular mechanism resulting in the increased induction of apoptosis with radiosensitisation will be investigated in this in vitro study. Knowledge of the apoptotic pathway might lead to a more efficient design of in vivo and clinical studies considering the application of the chemoradiotherapy combination in a clinical setting.

Project

In vitro study of the apoptotic signal transduction pathway necessary for radiosensitisation. Historic

University of Antwerp

The combination of chemo- and radiotherapy is a promising treatment of cancer. This combination results often in an increase of apoptotic cell death. The molecular mechanism resulting in the increased induction of apoptosis with radiosensitisation will be investigated in this in vitro study. Knowledge of the apoptotic pathway might lead to a more efficient design of in vivo and clinical studies considering the application of the chemoradiotherapy combination in a clinical setting.

Project

In vitro study of the neuro-immune interaction between mucosal mast cells and extrinsic sensory, primary afferent neurons in mice infected with Schistosoma mansoni. Historic

University of Antwerp

In vitro study of the neuro-immune interaction between mucosal mast cells and extrinsic sensory, primary afferent neurons in mice infected with Schistosoma mansoni.

Project

In vitro study on the combination of afatinib with gemcitabine and irradiation under normoxic versus anoxic conditions in cetuximab sensitive and resistant HNSCC cell lines Recently ended

University of Antwerp

Resistance to cetuximab is a main clinical problem in cancer patients. Therefore, we have generated an in vitro HNSCC model of acquired cetuximab resistance and would like to investigate if afatinib, a dual kinase inhibitor specific for EGFR and HER, will overcome this acquired resistance.

Project

In vitro susceptibility of Leishmania (Leishmania) donovani to antimonials and the effector mechanisms of the macrophage: what is the best marker for treatment failure? Historic

University of Antwerp

Visceral leishmaniasis (VL) is a tropical parasitic disease due to infection with Leishmania (Leishmania) infantum or Leishmania (Leishmania) donovani that primarily affects the liver, the spleen and the bone marrow. Worldwide, antimonials are the first line treatment of VL, but in some regions, as North-East India and the bordering regions in Nepal, treatment failure due to the parasite has emerged and seems to be spreading. This project will contribute to a better understanding of (i) the i...

Project

In vitro systems for the immortalization of multiple myeloma plasma cells and their precursors. Historic

Vrije Universiteit Brussel

Multiple myeloma related cells expressing different isotypes can he found in bone marrow and peripheral blood using a patient-specific RT-PCP method, based on the CDR regions in the immunoglobulin gene expressed by the myeloma cells. When the myeloma cell expresses IgG, IgA sequences and sometimes IgM sequences with the same variable region and the same somatic mutations, can be detected. The nature of these myeloma related cells is unknown. Do they belong to the malignant clone, are they pr...

Project

In vitro systems for the immortalization of multiple myeloma plasma cells and their precursors. Historic

Vrije Universiteit Brussel

Expression and function of prolactin in the immune system. Prolactin (PRL) is mainly produced by the anterior pituitary under the control of the transcription factor Pit-1. PRL stimulates lactation and is involved in mammary development and many other processes. The stimulating effects of PRL on the development of hemopoietic cells and leukocyte functions indicate that it acts as a hemopoietic growth and differentiation factor. PRL receptors and PRL are expressed by leukocytes, indicating tha...

Project

In vitro systems for the immortalization of multiple myeloma plasma cells and their precursors. Historic

Vrije Universiteit Brussel

Multiple myeloma related cells expressing different isotypes can he found in bone marrow and peripheral blood using a patient-specific RT-PCP method, based on the CDR regions in the immunoglobulin gene expressed by the myeloma cells. When the myeloma cell expresses IgG, IgA sequences and sometimes IgM sequences with the same variable region and the same somatic mutations, can be detected. The nature of these myeloma related cells is unknown. Do they belong to the malignant clone, are they pr...

Project

In vitro systems for the immortalization of multiple myeloma plasma cells and their precursors. Historic

Vrije Universiteit Brussel

Multiple myeloma related cells expressing different isotypes can he found in bone marrow and peripheral blood using a patient-specific RT-PCP method, based on the CDR regions in the immunoglobulin gene expressed by the myeloma cells. When the myeloma cell expresses IgG, IgA sequences and sometimes IgM sequences with the same variable region and the same somatic mutations, can be detected. The nature of these myeloma related cells is unknown. Do they belong to the malignant clone, are they pr...

Project

In Vitro Systems for the Immortalization of Multiple Myeloma Plasma Cells and Their Precursors. Historic

Vrije Universiteit Brussel

Multiple myeloma related cells expressing different isotypes can he found in bone marrow and peripheral blood using a patient-specific RT-PCP method, based on the CDR regions in the immunoglobulin gene expressed by the myeloma cells. When the myeloma cell expresses IgG, IgA sequences and sometimes IgM sequences with the same variable region and the same somatic mutations, can be detected. The nature of these myeloma related cells is unknown. Do they belong to the malignant clone, are they pr...

Project

In vivo active control of neuronal networks by clamping single-neuron excitability. Recently ended

University of Antwerp

A long-standing debate in neuroscience regards whether the neural code is based on the rate of spiking or on the precise timing at which action potentials in a neuronal network occur. In an alternative but equivalent formulation, what is more important and relevant for cognition, sensation and motor behavior, the number of spikes a neuron emits over a certain period of time, or the exact instants at which they occur? The aim of this project is to modulate in vivo the firing rate of a populati...

Project

In vivo analysis of the role of a newly identified screenings hit in breast epithelial homeostasis and basal breast cancer progression

Ghent University

The hit was identified in an siRNA screen as being crucial in ZEB-1 mediated EMT. Transcription factors essential in normal development play an important role in this process. Moreover, studies have shown that EMT is linked with (cancer)stem cells. This suggests an important function for our hit in normal breast development and the progression of basal breast cancer.

Project

In vivo and in vitro effects of colostrum and milk replacer on the enteric nervous system of the preterm piglet. Historic

University of Antwerp

Feeding human milk, when compared with formulated milk, results in a better growth and maturation of the gastrointestinal tract. These beneficial effects can be attributed, at least in part to the unique composition of human milk. Topic of this study will be to investigate to what extent these beneficial effects are mediated by a modulation of the morphology of the enteric nervous system in an in vivo and in vitro pig model.

Project

In vivo and in vitro study into vascular calcifications in case of chronic renal insufficiency. Historic

University of Antwerp

In vivo and in vitro study into vascular calcifications in case of chronic renal insufficiency.

Project

In vivo and in vitro study into vascular calcifications with chronic renal insufficiency. Historic

University of Antwerp

In vivo and in vitro study into vascular calcifications with chronic renal insufficiency.

Project

In vivo Bio Imaging Lab: supporting core facilities.

University of Antwerp

This project represents a research contract awarded by the University of Antwerp. The supervisor provides the Antwerp University research mentioned in the title of the project under the conditions stipulated by the university.

Project

In vivo characterisation of the interaction bteween angiotensine fragments with the central neurotransmitter system. Historic

Vrije Universiteit Brussel

Besides the well-known renin-angiotensin system (RAS) in the kidney, there exists a RAS in the brain. This central system also regulates blood pressure, but other functions such as motor control, learning and memory have been proposed. The main peptide of the RAS is angiotensin II (Ang II), that exerts its effects via AT1 and AT2 receptors. Recently, fragments of Ang II, such as Ang IV and Ang (1-7) have been suggested to influence the RAS and to have specific functions in the brain. Indeed, ...

Project

In vivo characterization of the interaction between angiotensin fragments and the central neurotransmitter systems Historic

Vrije Universiteit Brussel

Besides the well-known renin-angiotensin system (RAS) in the kidney, there exists a RAS in the brain. This central system also regulates blood pressure, but other functions such as motor control, learning and memory have been proposed. The main peptide of the RAS is angiotensin II (Ang II), that exerts its effects via AT1 and AT2 receptors. Recently, fragments of Ang II, such as Ang IV and Ang (1-7) have been suggested to influence the RAS and to have specific functions in the brain. Indeed, ...

Project

In vivo characterization of the medial superior olive.

KU Leuven

The medial superior olive is the mammalian nucleus in the brainstem where time comparisons are made between the sounds to the two ears, which contain information regarding the spatial position of the sound source. Because of their biophysical specializations towards fast temporal processing, these cells have small action potentials and are surrounded by large phase-locked local field potentials. The neurons are therefore very difficult to study in vivo with extracellular methods. In this proj...

Project

In Vivo En Multiplex Quantum Dot-Gebasserde Western Blot Analyse Door Gebruik Van Fluorescerende Beeldvormende Technologie Historic

Vrije Universiteit Brussel

Fluorescence has proven to be a multipurpose efficient tool for multiple applications including imaging and immunobloting. New developments in instrumentation, software, probes, and applications have resulted in a recent burst of popularity for fluorescence based techniques including western immunobloting and life imaging. Hereby we solicit the FWO krediet aan navorsers and the OZR to support a state of the art fluorescence iimaging technology using the KODAK Image Sation In-Vivo FX for both ...

Project

In vivo evaluation of bio-erodible minitablets for prolonged ocular drug delivery. Historic

University of Antwerp

Bioerodible sterilised minitablets (6 mg and diameter 2 mm) used as ocular drug delivery system, will be evaluated in humans. First of all, a clinical study comparing conventional eye drops and optimised minitablets containing ciprofloxacin (3%, w/w) will be performed in healthy volunteers to prove the effectiveness of the minitablet for sustained ocular delivery of ciprofloxacin. Secondly, after in vitro screening of new formulations for sustained release over a longer period of time, an in ...

Project

In vivo evaluation of new 99m Technetium-tricarbonyl complexes as potential tracers for myocardial perfusion imaging Historic

Vrije Universiteit Brussel

99mTc labelled radiotracers, such as 99mTc-sestamibi and 99mTc-tetrofosmin are widely used for myocardial perfusion imaging. However, both 99mTc-sestamibi and 99mTc-tetrofosmin are not ideal myocardial perfusion imaging agents. The aim of this project is to evaluate new tracers for cardiac perfusion. In collaboration with Prof Isabel Santos (Instituto Tecnológico e Nuclear - ITN) and Covedien.

Project

In Vivo Evaluation of the Antifibrogenic Properties of Trichostatin A and Analogues. Historic

Vrije Universiteit Brussel

Two years ago, we discovered that trichostatin A (TSA) is a potent antifibrogenic agent in cultures of stellate cells and skin fibroblasts. TSA retards the morphological changes during activation of stellate cells, suppresses synthesis of collagens I and III, inhibits expression of alpha-smooth muscle actin and cellular proliferation, and blunts TGF-beta induced ECM production. Because the external supply of TSA was very limited, Prof. A. Geerts and Prof. Dr. D. Tourwé started a program to sy...

Project

In vivo identification and validation of immune-suppressive signalling proteins and/or receptors involved in glioblastoma-mediated suppression of microglia.

University of Antwerp

Glioblastoma multiforme, the most common parenchymal brain tumor in adults, represents a great challenge to the brain's immune system. Despite a robust infiltration of microglia into the tumor, these immune cells do not appear immunologically active. In this research project, we aim to reactivate these tumor-infiltrating microglia by creating a local immune-stimulating environment, with tumor growth arrest and/or tumor rejection as main objectives.

Project

In vivo imaging of cell differentiation in cell therapy in a rat model of heart failure by means of pinhole SPECT. Historic

Vrije Universiteit Brussel

The project aims at the development and validation of the paMHC-hNIS transgenic rat model, allowing for the differentiation of stem cells into cardiomyocytes to visualize in vivo in a quantitative manner with pinhole SPECT (Single Photon emission tomography). The project includes 4 specific objectives: 1. imaging of the 3D distribution and intensity of the NIS transgene expression in the heart 2. Assessing the impact of the NIS transgene expression on cardiac function 3. use of paMHC-hNIS...

Project

In vivo imaging study into the neural substrate of songprocessing and memory in songbirds. Historic

University of Antwerp

Songbirds (i.e. Passeriformes) share with humans the capacity of vocal imitation. Like human speech is, is birdsong a complex natural learned behavior that requires memorization of the song of an adult tutor. The acquisition and production of songs is controlled by a circuit of brain regions, the song control system (SCS). Also the auditory system, responsible for perception and processing of auditory information, is critical for song learning. Song learning inquires hearing, listening and m...

Project

In vivo imaging study into the neural substrate of songprocessing and memory in songbirds. Historic

University of Antwerp

Songbirds (i.e. Passeriformes) share with humans the capacity of vocal imitation. Like human speech is, is birdsong a complex natural learned behavior that requires memorization of the song of an adult tutor. The acquisition and production of songs is controlled by a circuit of brain regions, the song control system (SCS). Also the auditory system, responsible for perception and processing of auditory information, is critical for song learning. Song learning inquires hearing, listening and m...

Project

In vivo magnetic resonance imaging study into the neural substrate of songprocessing and memory in songbirds. Historic

University of Antwerp

In vivo magnetic resonance imaging study into the neural substrate of songprocessing and memory in songbirds.

Project

In vivo microdialysis studies with topiramate Historic

Vrije Universiteit Brussel

1. Introduction: Topiramate is a new generation antiepileptic drug, used in clinical practice as an add-on treatment for patients suffering from intractable partial and secondarily generalized seizures. Its structure, a sulfamate-substituted derivative of D-fructose, is distinct from that of all other antiepileptic drugs (Shank et al., 2000). Several mechanisms of action have been attributed to topiramate: voltage-sensitive, use-dependent Na+ channel blockade (Zona et al., 1997; De Loren...

Project

In vivo microdialysis study of the release and metabolism of dopamine,serotonine,and amino acid neurotransmitters in rat basal ganglia and hippocampus Historic

Vrije Universiteit Brussel

This project concerns the application of single and dual probe techniques, coupled to microbore HPLC, for the pharmacological study of the release and metabolism of monoamine and amino acid neurotransmitters in rat CNS. The role of 5-HT receptor subtypes will be evaluated using local application of selective 5-HT recepotor agonists and antagonists in the hippocampus and the raphe nuclei: new generation antipsychotics (eg. risperidone), antidepressants and antiepileptics. The second part of th...

Project

In vivo modelling of two ulcero-mutilating neuropathies in Drosophila melanogaster

University of Antwerp

The aim of this project is to develop fruit fly models of two phenotypically similar neurodegenerative disorders of the peripheral nervous system, Charcot-Marie-Tooth type 2B and Hereditary Sensory Neuropathy type I. The wild-type and mutant versions of the responsible genes, RAB7 and SPTLC2, will be expressed in Drosophila melanogaster. This will allow us to investigate the pathomechanism of both diseases in great detail and to investigate the possibility of a shared etiology for both disord...

Project

In vivo molecular imaging researchnbsp;(IMIR).

KU Leuven

State of the art molecular imaging research expands its expertise by implementing new imaging technology and by widening the application scope of available imaging technology (e.g. positron emission tomography (PET), magnetic resonance imaging (MRI), bioluminescence).nbsp;This isachieved by developing specific tracers, contrast agents and reporter gene constructs for novel relevant imaging targets and validating them invivo in small animals with the aim to translate them to the clinic. In add...

Project

In vivo monitoring van neuropeptiden tijdens epileptische aanvallen met nano LC-MS/MS en karakterisering van hun mogelijke anticonvulsieve rol.

Vrije Universiteit Brussel

Neuropeptides play an important role when the CNS is challenged such as for instance during epileptic seizures. In order to obtain better insights into the central peptidergic effects, it is essential to monitor their concentration in the brain. Quantification of neuropeptides in dialysates is challenging due to their low extracellular concentrations (low pM range), their low microdialysis efficiencies, the need for acceptable temporal resolution, the small sample volumes, the complexity of t...

Project

In vivo MRI-research into the functional organisation of the brain of the canary (Serinus canaria) and the zebra finch (Taeniopygia guttata) using manganese as a tract tracing agent. Historic

University of Antwerp

In vivo MRI-research into the functional organisation of the brain of the canary (Serinus canaria) and the zebra finch (Taeniopygia guttata) using manganese as a tract tracing agent.

Project

In vivo MRI research of the relationship between plasticity of the song control nuclei and several aspects of song behaviour in the European Starling. Historic

University of Antwerp

In vivo MRI research of the relationship between plasticity of the song control nuclei and several aspects of song behaviour in the European Starling.

Project

In vivo non-invasive imaging of acute myeloid leukemia (AML) immunotherapy in mice. Historic

University of Antwerp

In this project we will examine the effect of an autologous tumor vaccine on survival in a mouse model of acute myeloid leukemia. The vaccine will consist of autologous tumor cells, injected together with Toll-like receptor ligands. The tumor and its environment will be studied using bioluminescence and flow cytometry.

Project

In vivo non invasive imaging of immunotherapy for acute myeloid leukemia in mice.

University of Antwerp

The aims of this project are to test the implementation of non invasive imaging techniques to monitor tumor growth and/or elimination in an AML mouse model, as well as to test the efficacy of an autologous whole tumor cell vaccine. We will investigate if stable expression of reporter genes by murine AML cells will allow us to monitor tumor progression using bioluminescence and flow cytometry as non invasive techniques.

Project

In vivo non-vasive imaging of acute myeloid leukemia (AML) immunotherapy in mice. Recently ended

University of Antwerp

This project represents a research awarded by the University of Antwerp. The supervisor provides the Antwerp University research mentioned in the title of the project under the conditions stipulated by the university.

Project

In vivo quantification and characterization of neuro-plasticity in the adult brains of songbirds. Historic

University of Antwerp

In vivo quantification and characterization of neuro-plasticity in the adult brains of songbirds.

Project

In vivo structure-function analysis of the atonal transcription factor. Recently ended

KU Leuven

The experiments proposed herein constitute the first time an extensive structure-function analysis in the endogenous locus has been carried outfor a proneural genes. The very high efficiency with which we are able to replace the Atonal locus, means that generating the various necessarychimeras in the locus will be achieved with minimum effort. This allowsus to focus most of our efforts on the functional analysis of these variants. We are confident these analyses will generate not only novel, ...

Project

: In vivo study of optineurin in inflammation and autophagy

Ghent University

With this study we want to understand the function and regulation of optineurin in intestinal homeostasis and inflammation in vivo. Although optineurin was identified as a negative regulator of NF-B-dependent inflammation and was suggested as a key component of pathogen-induced autophagy, the physiological role of optineurin has not been defined. Our approach will be the development and phenotypical characterization of cell-specific optineurin deficient mice, and their study in established m...

Project

In vivo study of the functional role for type 1 and 2 cannabinoid receptors in neurodegeneration

KU Leuven

The endocannabinoid system (ECS) plays an important role in cerebral modulation of major neurotransmitters and in neuroinflammation. Both are central processes in neurodegeneration. The relative importance of type 1 and 2 cannabinoid receptors (CB1R and CB2R) in neurodegeneration is currently unknown, but needs to be identified in order toprovide proof-of-mechanism for possible ECS-based therapies for neuroprotective, cognition or motor-related pharmacological treatment. We will study the rel...

Project

In vivo study of the functional role for type 1 and 2 cannobinoid receptors in neurodegeneration. Recently ended

KU Leuven

The endocannabinoid system (ECS) is an important player in cerebral modulation of mono-aminergic neurotransmission and in the inflammatory changes that occur in neurodegeneration. In this project we want to investigate the role of the type 1 and 2 cannabinoid receptor (CB1R and CB2R respectively) as key effectors of the ECS in the pathophysiology and clinical expression of Alzheimer's disease, Huntington's and Parkinson's disease. By means of PET imaging using the selective radioligands 18F-M...

Project

In vivo study of the functional role of type 1 and type 2 cannabinoid receptors in neurodegeneration.

KU Leuven

Het endocannabinoïd systeem (ECS) is een belangrijke modulator van neurotransmissie in de hersenen en van inflammatoire veranderingen, en is daardoor sterk betrokken bij neurodegeneratie. In dit project wensen we derol van de type 1 en 2 cannabinoid receptor (CB1R resp. CB2R) te bestuderen als sleutel-effectoren van het ECS in de pathofysiologie en klinische expressie van de ziekte van Alzheimer, Huntington en Parkinson. Door middel van PET beeldvorming met de nieuwe selectieve liganden 18F-M...

Project

In vivo study of transcriptionregulation in hyperthermophilic archaea of the genus Sulfolobus Historic

Vrije Universiteit Brussel

Ss-LrpB from Sulfolobus solfataricus is an ideal model system for the study of transcription regulation in the hyperthermoacidophilic archaea. The construction of a gene disruption mutant has led to a breakthrough in this study, and was the first disruption mutant of an archaeal regulator gene generated in S. solfataricus. On the basis of this experience we will further study the physiological role of Ss-LrpB, construct an overexpression strain and generate promoter/operator gene fusions. Th...

Project

In vivo study of transcriptregulation in hyperthermoacidofyl archea belonging to genus ulfolobus Historic

Vrije Universiteit Brussel

In vivo study of transcriptregulation in hyperthermoacidofyl archea belonging to genus ulfolobus

Project

In-vivo visualisation and quantification of endogenous neuronal stem cell recruitment in the songbird brain using imaging methods (BLI and MRI). Recently ended

University of Antwerp

This project aims at visualising and quantifying endogenous neuronal stem cell recruitment in the brain of living songbirds using Bioluminescent Imaging (BLI) with the reporter gene luciferase and Magnetic Resonance Imaging (MRI) using either the reporter gene Ferritine or MRI contrast agents that are internalised by the neuronal progenitor cells in the subventricular zone. The developed tools will then be used to study the underlying mechanisms of seasonal changes in neuronal recruitment.

Project

In vivo visualization of dendritic cell migration and nanobody targeting of small animals by means of multi-modality imaging: SPECT-CT-Optical. Historic

Vrije Universiteit Brussel

In vivo visualization of dendritic cell migration and nanobody targeting of small animals by means of multi-modality imaging: SPECT-CT-Optical. not available

Project

Invloed nagaan van technieken (apparaten die een ondulerend mechanisme produceren en van een IR warmte bron die toepasbaar zijn op de microcirculatie van proefdieren) op de vasomotoriek van bloed- en lymfevaten door middel van transilluminatie microsco...

Vrije Universiteit Brussel

The research institute 'VUB' and the 'Home Health Products (HHP)' have entered into a service-agreement concerning the project' Invloed nagaan van technieken (apparaten die een ondulerend mechanisme produceren en van een IR warmte bron die toepasbaar zijn op de microcirculatie van proefdieren) op de vasomotoriek van bloed- en lymfevaten door middel van transilluminatie microscopie in vivo. '. The research results can be transferred to the company, there can be a reasonable return in case of c...

Project

Invloed van de microstructuur op de textuur van broodkruim.

KU Leuven

In de voedingsindustrie wordt veelvuldig gebruik gemaakt van empirischemeetmethoden om zowel de reologie als de textuur van levensmiddelen te evalueren. Empirische methoden zijn populair omdat ze ons in staat stellen om snelle, efficiënte metingen uit te voeren. Verder worden ze ook vaak gebruikt wanneer de reologie of de structuur van het staal te complex(bijvoorbeeld: niet homogeen, isotroop) is voor een fundamentele benadering. Deze methoden zijn vaak waardevol wanneer ze goed correleren m...

Project

Invloed van EPS op slibdesintegratie en anaerobe vergisting van waterzuiveringsslib

KU Leuven

EPS-structuren bepalen in grote mate de fysische & chemische eigenschappen van slib en daarmee verbonden de "sterkte" van het slib en de weerstand tegen desintegratie en anaerobe vergisting. In dit onderzoek wordende EPS-structuren in slibvlokken van verschillende oorsprong gekarakteriseerd en geanalyseerd. Deze structuren zullen dan gelinkt worden aan deintensiteit van de desintegratiemethode en aan de anaerobe vergistbaarheid voor en na de desintegratie.

Project

Invloed van grondstoffen en procesvoering op de structuur van gel-type geëmulgeerde vleeswaren

KU Leuven

De doelstelling van het voorgestelde onderzoek bestaat erin wetenschappelijk onderbouwd inzicht te verschaffen in de structuur van gel-type geëmulgeerde vleeswaren. Hierbij wordt gefocust op de relatie tussen (1) structuurvormend potentieel van grondstoffen (magere vleesfractie en vetfractie met daarin lipiden, myofibrillaire proteïnen en collageen), (2) thermische procesvoering en (3) micro- en macroscopische structuur van heteindproduct (kookworst als typevoorbeeld). Deze aanpak zal toelate...

Project

Invloed van Maternale transitie van omega 3 vetzuren op uitkipping, kuikenkwaliteit en performantie tot op slachtleeftijd.

KU Leuven

Title: Effect of maternal transition of omega-3 fatty acids on hatchability, chick quality and performance till slaughter.Aim: The main goal of this study is to explore alternative feedstrategies including ω-3 fatty acids (pre- and post hatch) tooptimize hatch, viability and performance of the offspring by the immune modulating capacity of ω-3 fatty acids and by reducing mortality percentage.This study comprises 3 sub-goals:1. Investigate the transition of ω-3 fatty acids from ...

Project

Invloed van vruchtwisseling en N-bemesting op de wortelontwikkeling van maïs en het effect op de nutriëntenopname-efficiëntie Historic

University College Ghent

Toegepast onderzoeksproject in het kader van het Landbouwcentrum voor Voedergewassen Doelstelling: -Effect van vruchtwisseling en N-bemesting op de groeisnelheid van maïswortels en de wortelpatronen in de bodem -Relatie tussen wortelontwikkeling van maïs en opbrengst en nutriëntenopname van maïs

Project

Involvement of ascorbate in plant cell growth and protection against stress. Historic

University of Antwerp

Ascorbate (vitamin C) plays an essential role in the scavenging of reactive oxygen species. This function is being investigated in plant cells. Special attention is given to aspects of ascorbate transport at the plant plasma membrane, the effect of ascorbate on growth of cell cultures and its involvement against various stress factors (e.g. heavy metals, biotic stress factors).

Project

Involvement of nitric oxide pathway in activating endothelial progenitor cells towards homing after myodardial ischaemia. Historic

University of Antwerp

Involvement of nitric oxide pathway in activating endothelial progenitor cells towards homing after myodardial ischaemia.

Project

Involvement of the endoplasmic reticulum stress response in lung dendritic cell function and inflammatory lung disease Recently ended

Ghent University

Dendritic cells (DCs) are essential for the pathogenesis of inflammatory lung diseases. Many environmental triggers of lung diseases induce endoplasmic reticulum (ER) stress in lung cells. We hypothesize that ER stress is an endogenous danger signal in DCs, which will impact in the development of lung inflammation. This project will unveil the relevance of the ER stress in lung DC subsets in vivo.

Project

Involvement of the nitric oxide pathway in activating endothelial progenitor cells toward homing after myocardial ischaemia. Historic

University of Antwerp

Involvement of the nitric oxide pathway in activating endothelial progenitor cells toward homing after myocardial ischaemia.

Project

Involving volunteers and their effect on the governance and functioning of private non-profit organisations. Recently ended

Vrije Universiteit Brussel

Involving volunteers and their effect on the governance and functioning of private non-profit organisations.

Project

In what extent is the reception of literary works depending on gender-specific differences? Historic

Vrije Universiteit Brussel

It is the main aim of the research group to analyze gendered imaginations and stereotypes in literature. The members of the research group are specialists of German language and literature. Applying feminist linguistic theories on the interpretation of literary works can reveal very interesting new points of view. The interdisciplinary research group proves to be very attractive to young researchers from other Belgian universities. The participants meet once a month and give lectures about r...

Project

In words and deeds. The contribution of theology and theologians to therepression of heresy and the catholic reformation (1519-1587). Recently ended

KU Leuven

Dit onderzoek bestudeert hoe theologische kennis werd ingezet als instrument in de ketterbestrijding en de katholieke hervorming in de 16e eeuw. Daarom wordt eerst de academische theologie onderzocht zoals deze aan de Leuvense theologische faculteit werd ontwikkeld en gedoceerd, als eendynamisch kennissysteem, specifiek in relatie tot de protestante leerstellingen en het internationale politiek-religieuze debat. Zo krijgen we een globaal inzicht in de dynamische werking van een dominant weten...

Project

IOB Evaluation 'directe financiering NGO's'. Recently ended

University of Antwerp

Participation in the reference group to advise the Director IOB to support the quality of research and to give feedback of the research results.

Project

IOB evaluation of the Dutch policy towards the Arab region (2009-2013).

University of Antwerp

This project represents a formal service agreement between UA and on the other hand Min. Buitenlandse Zaken (NL). UA provides Min. Buitenlandse Zaken (NL) research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

IOFm/07/005 Christ Frauke.

KU Leuven

Drug discovery platform for novel anti-HIV targets.Drug discovery targeting LEDGF/p75.

Project

IOF mandate Debora Dumont / Inge Smolders Historic

Universiteit Hasselt

IOF mandates are mandates of permanent appointment for postdoctoral researchers that offer a structural support in the valorisation of research results of a research institute or group. The function of an IOF mandate is embedded in the structure of a research institute or group and, depending on the needs of the requesting institution or group, can vary between the profile of a business developer to a staff member whose research expertise is essential in order to facilitate services towards c...

Project

IOF-mandate Jan Van Den Bergh Historic

Universiteit Hasselt

IOF mandates are mandates of permanent appointment for postdoctoral researchers that offer a structural support in the valorisation of research results of a research institute or group. The function of an IOF mandate is embedded in the structure of a research institute or group and, depending on the needs of the requesting institution or group, can vary between the profile of a business developer to a staff member whose research expertise is essential in order to facilitate services towards c...

Project

IOF Mandate Mieke Haesen

Universiteit Hasselt

The goal of the project is the realization of various valorisation projects based on the know-how of EDM. More specifically, an expanded range of services for third parties is developped (companies or other organizations), based on the methodological and scientific-technological expertise of the Human-Computer Interaction (HCI) group of EDM. The expertise in the field of "User-Centred Software Engineering" (UCSE) approaches - usually shortened translated as User-centric software development -...

Project

IOF Program ETRO

Vrije Universiteit Brussel

Electricity ETRO (Department of Electronics and Informatics) hosts four collaborating research groups: the Laboratory for Micro- & Optoelectronics (LAMI), the Image Processing and Machine Vision Group (IRIS), the Laboratory for Digital Speech and Audio Processing (DSSP), and the Laboratory for Digital Telecommunications and Parallel & Distributed Processing (TELE). For all groups, strategic research in support of innovation is the main driving force for the R&D. In 2005-2010, we want to inve...

Project

IOF proof of Concept: Clinical translation of gene therapy for hemophilia, consolidation of a spin-off company

Vrije Universiteit Brussel

Haemophilia (/hi?m??f?li?/; also spelled hemophilia in North America, from the Greek haima ???? 'blood' and philia ????? 'love'[1]) is a group of hereditary genetic disorders that impair the body's ability to control blood clotting or coagulation, which is used to stop bleeding when a blood vessel is broken. Haemophilia A (clotting factor VIII deficiency) is the most common form of the disorder, present in about 1 in 5,000-10,000 male births.[2] Haemophilia B (factor IX deficiency) occurs in ...

Project

IOF-Proof of Concept:PreSSUB

Vrije Universiteit Brussel

VUB PreSSUB project: pre-hospital stroke study,Consequences of stroke, Specialized stroke care, Solving the problem

Project

ion Chromatography Recently ended

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Recticel. The research institute TANC provides Recticel research results on 'Ion Chromatography' under the conditions as stipulated in the present contract.

Project

Ionic and molecular recognition at modified membrane surfaces and its application to chemical and biosensing. Historic

University of Antwerp

Apart from exchange of researchers and information, the project aims at the synthesis of novel organic compounds : (i) calix[n]pyrroles, arylboronic acids, dendrimers (KUL) and (ii) conjugated oligomers and polymers comprising vinylthiophenes, vinylaryl units and their acetylene analogs (UIA). The compounds will be tested in modified membranes for recognition of neutral and ionic species (Poland, PAN).

Project

Ionic Liquid Redox Flow Batteries (IREBAT).

KU Leuven

Redox flow batteries store chemical energy in the form of dissolved redox couples. Electricity is generated in a separate power module. During discharge, the two electrolytes flow from separate storage tanks to the electrolysis cell for the redox reaction, with ions transferred between the two electrolytes across an ion-exchange membrane. During the recharging step, the process is reversed. Advantages are that flow batteries are easy to scale up (kWh to 100’s MWh), have high power density and...

Project

Ionic liquids. Recently ended

KU Leuven

Ionic liquids are organic salts with a low melting point (typically lower than 100 °C). These compounds have interesting properties like anegligible vapor pressure, a broad liquidus range (up to 400 °C), a wide electrochemical window (up to 5 V), a high electrical conductivity and physicochemical properties that can be tuned by a proper choice ofthe anion and cation. These properties make ionic liquids of interest as environmetally friendly alternatives for volatile organic solvents in cataly...

Project

Ionic liquids as solvents for the synthesis and processing of PPTA.

KU Leuven

Poly-paraphenylene terephtalamide (PPTA) is most known for its very high tensile strength . This synthetic fibre is therefore used in high-strength applications: personal armor, composite materials, automotive industry and sports equipment. The very high tensile strength of PPTA ispartly attributed to the large amount of intermolecular hydrogen bonds formed between the different polymer chains. However, those large amounts of intermolecular hydrogen bonds make the polymer not soluble in class...

Project

Ionic liquids with thermomorphic behaviour.

KU Leuven

Ionic liquids (ILs) are solvents that consist entirely of ions. They have special properties such as a negligible vapor pressure and an intrinsic electrical conductivity. Ionic liquids can be divided into hydrophilic ionic liquids which are totally miscible with water and hydrophobic ionic liquids which are immiscible with water. Ionic liquids can also showa temperaturedependent miscibility with water. Some IL/solvent mixtureshave an upper critical solution temperature (UCST). They form one h...

Project

Ionic transport in solids: electrical analysis in combination with ESR.

KU Leuven

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Project

Ion mobility high resolution mass spectrometer: a strong tool for fragile structures.

University of Antwerp

This project has two general objectives: (1) Increase the research potential of the UA by introduction of new state of the art techniques for the analysis of fragile molecular structures by using the novel ion mobility capabilities that have recently been integrated with high-mass high-resolution Q-TOF mass spetrometry ("Synapt", waters). (2) Maintain the current capacity to obtain Q-TOF data by replacing an existing system.

Project

IPC cleanliness measurement of ionic impurities Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties IMOTANC (research institute at Hasselt University), and on the other hand, Barco. The research institute IMOTANC provides Barco research results on 'IPC cleanliness measurement of ionic impurities' under the conditions as stipulated in the present contract.

Project

"I Promessi sposi" as a "hypotext": "continuations" in prose and adaptations for opera libretti Historic

Vrije Universiteit Brussel

This research project primarily focuses on those historical novels which are commonly defined as mere "continuations" of Manzoni's I Promessi sposi. Although these novels were influenced in a significantly more direct way than other texts of that same period, literary critics have so far insufficiently attended to this influence. Considering that they received unanimous critical acclaim upon publication, it is surprising at the very least that modern researchers have shown hardly any interest...

Project

IPSOC:Investigating Patient Satisfaction with oral anti-cancer treatment. Recently ended

KU Leuven

The aim of this study is to evaluate the patient perspective in the useof oral anti-cancer drugs. The following aspects will be investigated: 1) intrinsic desire for information about treatment; 2) patient satisfaction with treatment information and with treatment; 3) medication adherence; 4) health-related quality of life; and 5) the role of different health care professionals in the treatment of patients with oral anti-cancer drugs.This study should reveal information necessary for the deve...

Project

IQ - Inductive queries for mining patterns and models. Historic

University of Antwerp

Given the present distinct lack of a generally accepted framework for data mining, the quest for such a framework is a major research priority. The most promising approach to this task is taken by inductive databases (IDBs), which contain not only data, but also patterns. Patterns can be either local patterns, such as frequent itemsets, which are of descriptive nature, or global models, such as decision trees, which are of predictive nature. In an IDB, inductive queries can be used to generat...

Project

IR3 interferometer

Vrije Universiteit Brussel

The "Improved Infrared Interferometer" (IR3) is a phase-measuring interferometer, operating at a wavelength of 1550 nm, which is being developed for measuring the thickness and thickness variation of low-doped silicon wafers with diameters up to 300 mm. The purpose of the interferometer is to produce calibrated silicon wafers, with a certified measurement uncertainty, which can be used as reference wafers by wafer manufacturers and metrology tool manufacturers.

Project

IR admission of a polyester Historic

Universiteit Hasselt

This project represents a formal service agreement between the parties SBG(research institute at Hasselt University), and on the other hand, Sumitomo Bakelite Europe. The research institute SBG provides Sumitomo Bakelite Europe research results on 'IR admission of a polyester' under the conditions as stipulated in the present contract.

Project

IR and Raman spectra of a SiO powder Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties IMOTANC (research institute at Hasselt University), and on the other hand, Umicore. The research institute IMOTANC provides Umicore research results on 'IR and Raman spectra of a SiO powder' under the conditions as stipulated in the present contract.

Project

IRC/DRC Governance Sector Strategy Analysis. Recently ended

University of Antwerp

This project represents a formal service agreement between UA and on the other hand ODI. UA provides ODI research results mentioned in the title of the project under the conditions as stipulated in this contract.

Project

IRCP-SVA Research Consortium

Ghent University

A quantitative and qualitative growth of policy-aimed and fundamental research has driven the current consortium to its organisatorial limits. De facto, there is insufficient capacity and coordination to achieve further expansion of the research component within the consortium, such as in-depth preparations of major projects, as well as their management. Examples of those are European framework programmes and GOA&apos;s. The current situation neither allows for the conceptualisation and start...

Project

IREAD. Recently ended

KU Leuven

The iRead+ project aims at developing an intelligent reader based on text, audio and visual materials made available via e-reader or tablet PC.iRead+ addresses a broad public ranging from general readers to language learners and struggling readers. The intelligence of the reader shouldbe situated mainly on the level of the enrichment of the textual and multimedia material. Three types of annotation techniques will be studied to this end: linguistic annotations, socio-collaborative annotations...

Project

IRISnet II: Analysis of international best practice of Fibre optic broadband networks in cities. Historic

Vrije Universiteit Brussel

In Europe many cities are considering to invest in or stimulate the development of fibre networks. This report was commissioned by the Centre for Informatics of the Brussels Region (CIBG) in view of the future of its existing fibre optic network IRISNET. This report starts from the assumption that the first aim of the future IRISNET II will remain the connection of administrative and public service sites to a fully converged, high performance and future proof broadband fibre network. The main...

Project

IRIS: Pathogenesis, clinical and public health aspects. Recently ended

University of Antwerp

The pathogenesis, the clinical manifestations and the public health aspects of the Immune reconstitution inflammatoy syndrome (WS) will be studied. In Uganda and Ethiopia we will study how frequent a smear negative pulmonary TB patient with IRIS can become smear positive, and what the effect is of lRIS on the health service and the treatment adherence of the patient. Using blood samples obtained during a cohort study in Uganda, we will study whether VitD deficient; and the M. tuberculosis (TB...

Project

Iron-mediated catastrophic shifts in peatlands: positive feedbacks and phytotoxicity.

University of Antwerp

In this study, I aim to conduct fundamental research on a set of biogeochemical processes that, after rewetting, inhibit a shift from a drained (previously peat-accumulating) organic soil with net decomposition towards a soil with organic matter accumulation and nutrient retention. The emphasis will be on positive feedback loops on OM decomposition, with experiments to elucidate the effects of water table dynamics, iron chemistry and vegetation assembly.

Project

Irony and Space Recently ended

University College Ghent

This doctoral thesis takes my own artistic practice as a starting point. As of 2002 I have exchanged my status of performance artist for that of sculptor. In my practice, I engage irony as a means of auto-creation. To my mind, art is primarily a matter of finding a certain degree of personal freedom. In my work, I wish to bring certain matters up for discussion in an organic, plastic, non-narrative way. These matters include the position and autonomy of art, the artist and the individual, and...

Project

Irreversibility and efficiency in small-scale systems Recently ended

Universiteit Hasselt

In contrast to the time-reversible microscopic laws of physics, most macroscopic phenomena are time-irreversible. Recently, exact expressions were obtained for entropy production and thermodynamic efficiency. We will check in this research project how these results can be applied to small scale systems such as two-dimensional quantum dots, classical Coulomb clusters, photo-electric and photo-chemical devices. In such systems, fluctuations are prominent and they determine to a large extend the...

Project

Irreversibility and efficiency in small-scale systems

Universiteit Hasselt

In contrast to the basic microscopic laws in physics, which are symmetric on time reversal, most macrocopic phenomena are characterized by irreversible behavior. Recently exact expressions for the entropy production and thermodynamical efficiency were proposed. Within this project we want to investigate how these results can be applied to small-scale systems like two-dimensional quantum dots, classical Coulomb clusters, photoelectric and electro-chemical devices. Within such systems, fluctuat...

Project

Irreversibility and efficiency in small-scale systems.

University of Antwerp

In contrast to the basic microscopic laws in physics, which are symmetric on time reversal, most macrocopic phenomena are characterized by irreversible behavior. Recently exact expressions for the entropy production and thermodynamical efficiency were proposed. Within this project we want to investigate how these results can be applied to small-scale systems like two-dimensional quantum dots, classical Coulomb clusters, photoelectric and electro-chemical devices. The main goal of this project...

Project

IR spectroscopy of an additive Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Eftec. The research institute TANC provides Eftec research results on 'IR spectroscopy of an additive' under the conditions as stipulated in the present contract.

Project

IR spectrum of an adhesive Historic

Universiteit Hasselt

This offer represents a formal service agreement between the parties TANC (research institute at Hasselt University), and on the other hand, Eftec nv. The research institute TANC provides Eftec nv research results on 'IR spectrum of an adhesive' under the conditions as stipulated in the present contract.

Project

ISAIF10 conferentie (10th International Symposium on Experimental and Computational Aerothermodynamics of Internal Flows) 4-7 juli 2011.

Vrije Universiteit Brussel

ISAIF10 conferentie (10th International Symposium on Experimental and Computational Aerothermodynamics of Internal Flows) 4-7 juli 2011.

Project

Is auxin involved in the growth inhibition of the leaves of Arabidopsis thaliana in response to drought stress? Historic

University of Antwerp

The role of the growth regulating plant hormone auxin in the response to abiotic stresses such as drought has hardly been investigated to date. Based on micro-array data we have strong indications that the expression of 45 auxin response genes is specific for dividing cells and is strongly affected by drought. In this project mutants for these genes will be isolated and tested for their effect on growth under optimal and drought conditions.

Project

i-SCOPE: Interoperable Smart City services through an Open Platform for urban Ecosystems

Vrije Universiteit Brussel

The latest generation of 3D Urban Information Models (UIM) can be used to create smart web services based on geometric, semantic, morphological and structural information at urban scale level, which can be used by local governments to: Improve decision-making on issues related to urban planning, city management, environmental protection and energy consumption based on urban pattern and its morphology. Promote inclusion among various users groups (e.g. elder or diversely able citizens...

Project

iSEED-Innovation on stability, spectral and energy efficiency in DSL. Historic

Vrije Universiteit Brussel

SELT measurements have proven to be useful for acquiring information on the make-up of a single DSL loop. Loops that run through the same binder may see common features in their SELT data, separate from the distinct features that indicate the end of the line. For the moment, this information is not used in the topology extraction of DSL loops. At the binder level we may expect a higher correlation in the features of lines pertaining to the same binder. The aim is to model this joint reaction ...

Project

Is efficiency all that matters? The role of non-efficiency considerations in the application of Article 101 TFEU (ex Article 81 EC): the case of the audiovisual and telecommunications sectors. Historic

Vrije Universiteit Brussel

My Ph.D examines the role of non-efficiency considerations in the application of the EU competition rules, more specifically the 'antitrust' rule concerning agreements between undertakings (Art. 101 TFEU, ex Art. 81 EC). The main observation underlying the study is that both the character and objectives of EU competition law have changed fundamentally in the 50 years of EU competition law enforcement. Between 1962 and today the EU competition law regime has evolved - similar to earlier develo...

Project

Is everybody black in the mine? Material culture and daiy life of the Limburg miners, 1900 - 1960 Historic

Vrije Universiteit Brussel

The project researches everyday, banal behavior of Limburg working-class families in the 20th century (up to 1970). Particular emphasis is put on the "lived experiences" that are approached via photographies.

Project

Is GABA-A receptor a therapeutic target for the fragile X syndrome ? Historic

University of Antwerp

Recently, we found differential expression of the delta subunit of the -aminobutyric acid type A (GABAA) receptor in the brain of the fragile X knockout mouse, an animal model for the most frequent form of familial mental retardation. GABAA receptors have been implicated in anxiety, epilepsy, and learning and memory and numerous drugs of clinical importance bind to receptor. The purpose of this project is to increase our insights in the role the GABAA receptor in the fragile X syndrome using ...

Project

Is GABA-A receptor a therapeutic target for the fragile X syndrome ? Historic

University of Antwerp

Recently, we found differential expression of the delta subunit of the ?-aminobutyric acid type A (GABAA) receptor in the brain of the fragile X knockout mouse, an animal model for the most frequent form of familial mental retardation. GABAA receptors have been implicated in anxiety, epilepsy, and learning and memory and numerous drugs of clinical importance bind to receptor. The purpose of this project is to increase our insights in the role the GABAA receptor in the fragile X syndrome using...

Project

Is it really all about knowledge? Educators' perception on the process of changing ecological behavior.

University of Antwerp

Researchers agree that the environmental problems we face as a society are due to maladaptive human behavior. Environmental education (EE) is seen as a key instrument in reversing those problems. EE however does, however, seldom impact on children ecological behavior. Through a qualitative design we study educators' perception of the process of changing children's ecological behavior, as a mediator in the effectiveness of EE.

Project

Islamic identities in Flanders (1964-present). Historic

University of Antwerp

In this project, publicly accessible and elicited discourse produced by muslims is studied from the perspective of linguistic pragmatics, cultural history and ethnography. The research will be carried out in view of an analysis of the islamic political identities that are developing in muslim communities in Flanders since 1964.

Project

Islam in European Youth Literature Historic

Vrije Universiteit Brussel

It is the main aim of this project to comment on the images of Muslims in Flemish, Dutch, English, French, German and Spanish youth literature written in the last two decades (1980-2000). As youth literature is translated into many languages it is important to analyze it in an international framework, without limiting research to literature published in one nation and language. About fifty novels for young children and young adults will be commented on. As cultural and religious conflicts as...

Project

Islam instruction in state-funded schools: what is at stake? Historic

University of Antwerp

In situations where schools do not cater for the teaching of religious beliefs, this can lead to segregation of particular groups. At present there is not much information available on this topic (certainly not in a coherent way) and, on the other hand, research on the impact that the type of religious education in schools can have on segregation is needed because time and circumstances have changed, and policymakers did not yet cope with new challenges and unexpected developments, and regula...

Project

Island populations as a study model for fast evolution. Historic

University of Antwerp

From the very start (e.g. Darwin 1845, Wallace 1859), the faunas of island groups have played a special role in the growth of our understanding of evolutionary changes and speciation - and they continue to do so (e.g. Losos et al. 1997, 2004). Islands in archipelagos constitute repeated, discrete and relatively simple entities and therefore function as 'natura/laboratories' that can be used to test general theories (Whittaker 1998). The (often prominent) differences in phenotype (morphology, ...

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