Human anatomy and embryology University of Antwerp
The laboratory currently characterizes enteric neurons in embryonic and in adult zebrafish. Zebrafish is an excellent model system for the study of developmental disorders, including Hirschsprung disease (HSCR). In the intestines of patients with HSCR, the enteric ganglia are partially or completely absent, leading to motility disorders and chronic constipation, megacolon and eventually enterecolitis. One of the many available mutant zebrafish, ...