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The overall aim of the research of the Laboratory of Translational Genetics, is to unravel the genetic predisposition to cancer and to annotate somatic changes in solid tumors with the ultimate aim to discover and functionally validate genetic biomarkers for cancer therapies.

Topic A : Identification of new mutations in hereditary diseases (W. Lissens, I. Liebaers), more in particular: - cystic fibrosis - iduronate sulphate deficiency - Beta-glucuronidase deficiency - anti thrombosis III deficiency Topic B : Preimplantation genetics/expression (Liebaers I, Lissens W.) - expression Beta-hexosaminidase in mouse and human embryo's - preimplantation diagnosis in couples at risk for cysticfibrosis (F508) or couples at ...

In June 2016, the Laboratory of Tumor Immunology and Immunotherapy was founded at KU Leuven. In 2019 Prof An Coosemans, MD PhD, was appointed as the head of the lab. Currently, the lab counts one post-doc, four PhD students, one biostatistician and two lab technicians. The research philosophy of the lab is highly translational. By unraveling the immune biology in patients at diagnosis and during therapy/clinical trials (immune profiling), we ...