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Astrid De Boeck Ghent University
Joke Tommelein Ghent University
Hans Van Oosterwyck KU Leuven
Thomas De Bruyckere Vrije Universiteit Brussel
Tibbe Dhooge Ghent University
Sanne D'hondt Ghent University
Molecular biotechnology University of Antwerp
Biological role of ECM1 in the human skin. The extracellular matrix proteine 1 gene (ECM1) was isolated in our laboratory in 1994 and encodes for a secreted glycoprotein with a typical cystein CC-(X7-10)-C pattern. Four splice variants have been described so far: Ecm1a (540 aa), Ecm1b (415 aa), Ecm1c (559 aa) and a truncated protein of 57 aa. Ecm1 has been shown to play a role in endochondral bone formation, morphogenesis of the nephron and is a ...