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Immunity and Inflammation Research Group KU Leuven

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The main research topics include evaluation of leukocyte migration in inflammation and tumor biology with a main focus on chemokines. This includes biological and biochemical characterization of chemoattractants, their gene regulation and posttranslational processing, G protein-coupled receptor-mediated signal transduction, interactions with glycosaminoglycans and synergistic and antagonistic activities. The role of chemoattractants in (1) ...

Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven) KU Leuven

Responsible

The Lab of Molecular Oncology and Angiogenesis aims to shed light on the genetic and molecular mechanisms that regulate vessel shape remodeling and endothelial cell fate, with the overall aim of defining alternative therapeutic opportunities to improve anti-cancer therapy, as well as therapeutic angiogenesis for revascularization of ischemic tissues.

VIB Center for Inflammation Research Flanders Institute for Biotechnology

Responsible
The scientific investigation of the various research groups in the VIB-UGent Center for Inflammation research (IRC) is focused on molecular mechanisms of inflammation in pathologies such as allergy, autoimmune diseases, cancer, infectious diseases and senescence. At the heart of this research is the investigation of inter- and intracellular signaling pathways in innate and adaptive immune cells and barrier cells of the skin, lung and gut.

VIB CMN - Microglia and Inflammation in Neurological Disorders (MIND) lab University of Antwerp

Responsible
Microglia and neuroinflammation play a central role in the pathogenesis of Alzheimer's disease and other neurodegenerative disorders. Our primary focus is to examine the underlying molecular mechanisms that drive Alzheimer's disease (AD) and Frontotemporal dementia (FTD), with special focus on inflammatory networks and particularly the contribution of microglia. We use mouse models, iPSC and cutting-edge humanised mouse systems to determine the ...

Allergy and Clinical Immunology Research Group KU Leuven

Responsible

1. Allergy

Clinical research, cohort based, on drug hypersensitivity

Food allergy: clinical driven research into hidden allergens, co-factor enhanced food allergy, rare allergens (allergy to carmine, eatable insect allergens, WDEIA quality of life study etc…)

Mastocytosis and hymenoptera venom allergy and treatment: clinical prospective follow-up over 30 years of a large database of patients with hymentoptera venom ...