Stem Cell and Developmental Biology KU Leuven
Responsible
research
1. Pluripotent Stem Cells and Reprogramming
2. Pluripotent Stem Cell Differentiation
3. Adult Stem Cells
4. Disease Modelling and Regenerative Therapies
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Laboratory of Stem Cell and Developmental Neurobiology (VIB-KU Leuven) KU Leuven
Responsible
We want to force a breakthrough in the cure of neuronal and neurodegenerative disorders. This requires a deep understanding of normal brain function and translation of this knowledge into a solid mechanistic understanding of disease mechanisms.
Jan Schrooten KU Leuven
Laboratory for Molecular Cancer Biology (VIB-KU Leuven) KU Leuven
Responsible
The research program of the Laboratory for Molecular Cancer Biology is devoted to the analysis of pathways governing the genesis, progression and maintenance of cancer.Our current research efforts follow from our recent studies on the p53 tumor suppressor. p53 is a transcription factor that functions as a central component of most cellular stress responses. The outcome of p53-mediated surveillance is closely dependent on the type of stress ...
Zwi Berneman University of Antwerp
Jolanda van Hengel Ghent University
Laboratory for Experimental Hematology (LEH) University of Antwerp
Responsible
At the Laboratory of Experimental Hematology (LEH) headed by prof Zwi Berneman, we investigate novel concepts in personalized (stem) cell- and gene-based (immuno)therapies for personalized medicine. We perform fundamental, preclinical, translational and clinical research favoring a bench-to-bedside practice. For its translational and clinical research, LEH collaborates very closely with the Center for Cell Therapy & Regenerative Medicine ...
Ann De Becker Vrije Universiteit Brussel
Cell Differentiation Vrije Universiteit Brussel
Responsible
Our team wants to find ways to generate new insulin-producing, glucose-regulated "beta" cells that can be used for transplantation in diabetes patients and ways to regenerate beta cells in the pancreas. We study rodent experimental models as well as human cells. The first aim is based on tissue engineering starting from: 1. Exocrine pancreatic cells: reprogramming of adult exocrine cells to endocrine cells, or transdifferentiation in culture. ...