Researcher
Bert Houben
- Disciplines:Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences
Affiliations
- Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Sep 2014 → Today
Projects
1 - 4 of 4
- Assessing co-translational protein aggregation and the cellular factors that prevent itFrom1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Charge preference of the Mammalian protein quality control machineryFrom19 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Aggregation Gatekeepers and proteostasis in mammalian cellsFrom1 Oct 2020 → 30 Sep 2021Funding: BOF - postdoctoral mandates
- The role of aggregation gatekeepers in proteostasis.From10 Dec 2014 → 23 Jun 2020Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 22
- N-glycosylation as a eukaryotic protective mechanism against protein aggregation.(2024)
Authors: Bert Houben, Matthew Wilson, Joost Schymkowitz, Frederic Rousseau
Pages: eadk8173 - Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding(2023)
Authors: Laleh Khodaparast, Ladan Khodaparast, Emiel Michiels, Rodrigo Gallardo, Bert Houben, Frederic Rousseau, Joost Schymkowitz
- Reverse engineering synthetic antiviral amyloids (vol 11, 2832, 2020)(2023)
Authors: Emiel Michiels, Rodrigo Gallardo, Laleh Khodaparast, Ladan Khodaparast, Rob van der Kant, Bert Houben, Nikolaos Louros, Suzanne Kaptein, Guy Bormans, Johan Neyts, et al.
- Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein(2023)
Authors: Kobe Janssen, Filip Claes, Bert Houben, Mieke Nys, Laleh Khodaparast, Ladan Khodaparast, Nikolaos Louros, Rob van der Kant, Katerina Konstantoulea, Joost Schymkowitz, et al.
- Investigating the Sequence Determinants of the Curling of Amyloid Fibrils Using Ovalbumin as a Case Study(2022)
Authors: Joëlle Housmans, Bert Houben, Grigoria Tsaka, Nikolaos Louros, Sebastien Carpentier, Jan Delcour, Frederic Rousseau, Joost Schymkowitz
Pages: 3779 - 3797 - Protein structure and aggregation: a marriage of necessity ruled by aggregation gatekeepers(2022)
Authors: Bert Houben, Frederic Rousseau, Joost Schymkowitz
Pages: 194 - 205 - Heterotypic Amyloid β interactions facilitate amyloid assembly and modify amyloid structure(2022)
Authors: Katerina Konstantoulea, Nikolaos Louros, Bert Houben, Emiel Michiels, Joost Schymkowitz, Frederic Rousseau
- The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation(2021)
Authors: Bert Houben, Rodrigo Gallardo, Samantha Louise Edwards, Frederic Rousseau, Joost Schymkowitz
- Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness(2021)
Authors: Julien Mortier, Ronald Van Eyken, Laleh Khodaparast, Ladan Khodaparast, Bert Houben, Sebastien Carpentier, Frederic Rousseau, Joost Schymkowitz, Abram Aertsen
- Investigating the mechanism of action of aggregation-inducing antimicrobial Pept-ins(2021)
Authors: Guiqin Wu, Laleh Khodaparast, Ladan Khodaparast, Joëlle Housmans, Bert Houben, Joost Schymkowitz, Frederic Rousseau
Pages: 524 - +