Researcher
Tine Holemans
- Disciplines:Physiology, Molecular and cell biology
Affiliations
- Laboratory of Cellular Transport Systems (Division)
Member
From15 Sep 2009 → 31 Dec 2017 - Department of Cellular and Molecular Medicine (Department)
Member
From1 Aug 2009 → 14 Sep 2009
Projects
1 - 1 of 1
- Physiological role of the ATP13A2 gene product. A putative Mn2+ transporter.From15 Sep 2009 → 18 Oct 2016Funding: FWO fellowships
Publications
1 - 10 of 14
- Parkinson disease related ATP13A2 evolved early in animal evolution(2018)
Authors: Tine Holemans, Sarah van Veen, Shaun Martin, Norin Hamouda, Jan Eggermont, Peter Vangheluwe
- Novel form of complicated hereditary spastic paraplegia (SPG78), due to mutations in the ATP13A2/PARK9 gene(2017)
Authors: Teodora Chamova, Alejandro Estrada-Cuzcano, Shaun Martin, Tine Holemans, Albena Andreeva, Riet Rycke, Dae-In Chang, Sarah van Veen, Jean Samuel, Danny Sorensen, et al.
Pages: 379 - 380 - ATP13A2/PARK9 regulates endo-/lysosomal cargo sorting and proteostasis through a novel PI(3, 5)P2-mediated scaffolding function(2017)
Authors: Seyma Demirsoy, Shaun Martin, sahar Motamedi, Sarah van Veen, Tine Holemans, Chris Van den Haute, Veerle Baekelandt, Peter Vangheluwe, Patrizia Agostinis
Pages: 1656 - 1669 - Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78)(2017)
Authors: Shaun Martin, Tine Holemans, Sarah van Veen, Peter Vangheluwe
Pages: 287 - 305 - Unlocking the transport activity of the P5-type transport ATPases in neurodegeneration(2016)
Authors: Tine Holemans, Peter Vangheluwe, Frank Wuytack, Jan Eggermont
Number of pages: 156 - Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2(2016)
Authors: Shaun Martin, Sarah van Veen, Tine Holemans, Seyma Demirsoy, Chris Van den Haute, Veerle Baekelandt, Patrizia Agostinis, Jan Eggermont, Peter Vangheluwe
- A lipid switch unlocks Parkinson's disease-associated ATP13A2(2015)
Authors: Tine Holemans, Sarah van Veen, Shaun Martin, Chris Van den Haute, Veerle Baekelandt, Patrizia Agostinis, Frank Wuytack, Jan Eggermont, Peter Vangheluwe
Pages: 9040 - 9045 - Towards defining the substrate of orphan P5A-ATPases(2015)
Authors: Tine Holemans, Peter Vangheluwe
Pages: 524 - 535 - Unlocking ATP13A2/PARK9 activity(2015)
Authors: Shaun Martin, Tine Holemans, Peter Vangheluwe
Pages: 3341 - 3342 - Measuring Ca2+ pump activity in overexpression systems and cardiac muscle preparations(2014)
Authors: Tine Holemans, Ilse Vandecaetsbeek, Frank Wuytack, Peter Vangheluwe
Pages: 876 - 86