Researcher
Koen Debackere
- Disciplines:Hematology, Medical genomics
Affiliations
- Laboratory of Experimental Hematology (Division)
Member
From1 Aug 2017 → Today - Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven) (Division)
Member
From1 Oct 2016 → 31 Jul 2017
Projects
1 - 3 of 3
- Molecular characterization of hyperactive T cell receptor signaling in peripheral T cell lymphoma to uncover druggable targetsFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Genetic drivers of peripheral T-cell lymphomagenesisFrom1 Sep 2017 → 23 Nov 2022Funding: Foundations, funds and other with scientific goal
- AMPK: a master switch integrating metamoblism and immune effector functions in tumor-associated macrophagesFrom1 Oct 2016 → 30 Sep 2020Funding: FWO fellowships
Publications
1 - 10 of 13
- Therapeutic Targeting of JAK/STAT Signaling and Histone Acetyltransferase Activity in Post-Myeloproliferative Neoplasm Secondary AML(2023)
Authors: Koen Debackere
- Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma(2022)
Authors: Marlies Vanden Bempt, Koen Debackere, Sofie Demeyer, Quentin Van Thillo, Nienke Meeuws, David Nittner, Thomas Tousseyn, Jan Cools, Daan Dierickx
Pages: 2463 - 2476 - Genetic drivers of peripheral T-cell lymphomagenesis(2022)
Authors: Koen Debackere, Daan Dierickx, Gregor Verhoef, Jan Cools
- Primary mediastinal large B-cell lymphoma is characterized by large-scale copy-neutral loss of heterozygosity(2022)
Authors: Stefania Tuveri, Koen Debackere, Lukas Marcelis, Nicolas Dierckxsens, Jonas Demeulemeester, Eftychia Dimitriadou, Daan Dierickx, Lucienne Michaux, Jan Cools, Thomas Tousseyn, et al.
Pages: 603 - 615 - Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified(2021)
Authors: Koen Debackere, Lukas Marcelis, Sofie Demeyer, Marlies Vanden Bempt, Gregor Verhoef, Lucienne Michaux, Thomas Tousseyn, Jan Cools, Daan Dierickx
- In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy(2020)
Authors: Lukas Marcelis, Koen Debackere, Peter Vandenberghe, Gregor Verhoef, Francesca Bosisio, Xavier Sagaert, Daan Dierickx, Thomas Tousseyn
Pages: 1751 - 1766 - FER and FES tyrosine kinase fusions in follicular T-cell lymphoma(2020)
Authors: Koen Debackere, Thomas Tousseyn, Lukas Marcelis, Daan Dierickx, Peter Vandenberghe, Lucienne Michaux, Jan Cools
Pages: 584 - 588 - Coexisting driver mutations in MPN: clinical and molecular characteristics of a series of 11 patients(2018)
Authors: Laurien De Roeck, Lucienne Michaux, Koen Debackere, Peter Vandenberghe, Timothy Devos
Pages: 785 - 792 - α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming(2017)
Authors: Koen Debackere, Sarah-Maria Fendt
Pages: 985 - 994 - α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming(2017)
Authors: PS Liu, H Wang, X Li, T Chao, T Teav, S Christen, G DI Conza, WC Cheng, CH Chou, M Vavakova, et al.
Pages: 985 - 994