Researcher
Joachim Brouwers
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Drug Delivery and Disposition (Division)
Member
From1 Oct 2003 → 18 Aug 2022
Projects
1 - 9 of 9
- The impact of advanced age and age-related diseases on drug absorptionFrom10 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Improving preclinical assays to enhance the prediction of the in vivo behavior of oral drug productsFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Drug disposition in healthy volunteers and colorectal cancer patientsFrom1 Apr 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Oral drug absorption in specific patient populations: understanding the impact of gastrointestinal physiologyFrom1 Oct 2018 → 21 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Impact of the dynamic nature of the human gastrointestinal tract on drug and formulation behavior.From1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- The first hurdle in oral drug disposition: exploring the impact of gastric residence on drug behaviour in manFrom1 Oct 2013 → 25 Sep 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Implementation of crucial intraluminal processes in the simulation of intestinal absorption.From1 Jan 2013 → 31 Dec 2015Funding: FWO research grant KAN
- Development of biorelevant in vitro models as evaluation of supersaturating drug delivery systems based on in vivo characterization in humans.From1 Oct 2012 → 31 Dec 2016Funding: IWT personal funding - strategic basic research grants
- In vivo evaluation and in vitro prediction of the performance of supersaturating drug delivery systems in the gastrointestinal environment.From1 Oct 2009 → 30 Sep 2012Funding: FWO fellowships
Publications
1 - 10 of 109
- Corrigendum to "The effect of esomeprazole on the upper GI tract release and systemic absorption of mesalazine from colon targeted formulations" [Int. J. Pharm. 619 (2022) 121701].(2024)
Authors: Joachim Brouwers, Patrick Augustijns
Pages: 124087 - Expression of intestinal drug transporter proteins and metabolic enzymes in neonatal and pediatric patients.(2024)
Authors: Joachim Brouwers, Marc Miserez, Maissa Rayyan, Patrick Augustijns
Pages: 123962 - Investigating Tacrolimus Disposition in Paediatric Patients with a Physiologically Based Pharmacokinetic Model Incorporating CYP3A4 Ontogeny, Mechanistic Absorption and Red Blood Cell Binding(2023)
Authors: Matthias Van der Veken, Joachim Brouwers, Patrick Augustijns
- Gastrointestinal Fluid Volumes in Pediatrics: A Retrospective MRI Study. ( vol 14, 1935, 2022)(2023)
Authors: Matthias Van der Veken, Michael Aertsen, Joachim Brouwers
- Characterization of neonatal and infant enterostomy fluids-part II: Drug solubility(2023)
Authors: Tom de Waal, Joachim Brouwers, Maissa Rayyan, Patrick Augustijns
- Oral drug absorption in specific patient populations: understanding the impact of gastrointestinal physiology(2023)
Authors: Tom de Waal, Patrick Augustijns, Joachim Brouwers, Maissa Rayyan
- Characterization of neonatal and infant enterostomy fluids(2023)
Authors: Tom de Waal, Joachim Brouwers, Ilse Hoffman, Maissa Rayyan, Patrick Augustijns
- Characterization of Aspirated Duodenal Fluids from Parkinson's Disease Patients(2023)
Authors: Tom de Waal, Joachim Brouwers, Jan Tack, Wim Vandenberghe, Tim Vanuytsel, Patrick Augustijns
- The impact of inflammation on the expression of drug transporters and metabolic enzymes in colonic tissue from ulcerative colitis patients(2022)
Authors: Tom de Waal, Joachim Brouwers, Marc Ferrante, Séverine Vermeire, Tim Vanuytsel, Patrick Augustijns
- Gastrointestinal Fluid Volumes in Pediatrics: A Retrospective MRI Study(2022)
Authors: Matthias Van der Veken, Michael Aertsen, Joachim Brouwers, Patrick Augustijns
Patents
1 - 1 of 1
- Permeability model (Inventor)