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Researcher
Lut Overbergh
- Disciplines:Endocrinology and metabolic diseases
Affiliations
- Clinical and Experimental Endocrinology (Division)
Member
From1 Jul 2000 → Today - Department of Human Genetics (Department)
Member
From1 Oct 1999 → 30 Jun 2000
Projects
1 - 10 of 13
- Innovative strategies for screening, diagnosis and prevention of type 1 diabetes.From13 Dec 2022 → 15 Dec 2022Funding: BOF - various
- Citrullinated and deamidated neo-epitopes and their role in murine type 1 diabetes.From1 Jan 2020 → TodayFunding: FWO fellowships
- Translational approaches to disease modifying therapy of type 1 diabetes: An innovative approach towards understanding and arresting Type 1 diabetes – time to harvest.From15 Jul 2019 → 14 Jul 2021Funding: BOF - various
- The beta-cell and the immune system in type 1 diabetes: partners in crime - developing new therapies in type 1 diabetes through better understanding of beta-cell behaviour and use of novel immunomodulators.From1 Oct 2018 → TodayFunding: BOF - projects, Fund Recuperation Fiscal Exemption
- Neutrophils and post-translationally modified beta-cell proteins: a driving force behind type 1 diabetes?From1 Oct 2018 → 13 Nov 2023Funding: FWO fellowships
- Role of citrullination in the generation of autoantigens in Type 1 Diabetes.From1 Mar 2018 → 28 Feb 2021Funding: Foreign foundations, funds with scientific view
- Post-translational modification of GRP78 and its role in human Type 1 diabetesFrom1 Sep 2017 → 1 Jul 2022Funding: FWO fellowships
- The role of the post-translational modification citrullination in type 1 diabetesFrom21 Sep 2015 → 29 Jun 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of citrullination in the generation of autoantigens in type 1 diabetes.From1 Jan 2015 → 31 Dec 2017Funding: FWO research grant KAN
- A search for new pathways in the reversal and prevention of obesity and type 2 diabetesFrom30 Nov 2012 → 31 Oct 2016Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 126
- CD4+ T cells from individuals with type 1 diabetes respond to a novel class of deamidated peptides formed in pancreatic islets.(2024)
Authors: Rita Derua, Chantal Mathieu, Lut Overbergh
Pages: db230588 - An Insulin-Chromogranin A Hybrid Peptide activates DR11 restricted T cells in human type 1 diabetes.(2024)
Authors: Chantal Mathieu, Lut Overbergh
Pages: db230622 - Technical Validation and Utility of an HLA Class II Tetramer Assay for Type 1 Diabetes: A Multicenter Study.(2023)
Authors: Samal Bissenova, Lut Overbergh
Pages: 183 - 196 - Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory(2023)
Authors: Lut Overbergh, Chantal Mathieu
Pages: 1983 - 1996 - Gene expression signature predicts rate of type 1 diabetes progression(2023)
Authors: Lut Overbergh, Chantal Mathieu
- NET Proteome in Established Type 1 Diabetes Is Enriched in Metabolic Proteins(2023)
Authors: Samal Bissenova, Rita Derua, Chantal Mathieu, Conny Gysemans, Lut Overbergh
- 2D-DIGE Analysis of Liver Disease in Mice(2023)
Authors: Rita Derua, Lut Overbergh, Veerle Janssens
Pages: 231 - 244 - Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the importance of deamidation in neoantigen generation(2022)
Authors: Ylke Bruggeman, Chantal Mathieu, Lut Overbergh
- The role of deamidation as post-translational modification in type 1 diabetes(2022)
Authors: Aïsha Callebaut, Chantal Mathieu, Lut Overbergh, Mijke Buitinga
- Regulation of metabolism by protein modifications in autoimmunity(2022)
Authors: Lut Overbergh
Patents
1 - 1 of 1