Researcher
Aleyde Van Eynde
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 17
- Coordination of cell-cycle progression and DNA-damage repair by the protein phosphatase-1 regulator NIPP1From1 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- SUBSTRATE MAPPING AND ACTIVITY REGULATION OF PP1 HOLOENZYMESFrom1 Oct 2014 → 31 Dec 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting mitotic-exit phosphatases for cancer therapy.From1 Oct 2014 → 30 Sep 2019Funding: BOF - Concerted Research Project from 1994
- Targeting epigenetic regulators using bacterial macromolecule delivery.From1 Sep 2014 → 31 Aug 2019Funding: Other international institutions, not mentioned elsewhere
- Activation of protein phosphatase-1 as a novel cancer therapy.From1 Jan 2013 → 31 Dec 2016Funding: Private funding of national origin - undefined
- Functions of NIPP1 in keratinocyte biology and cutaneous wound repair.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- Regulation of ISWI-type chromatin remodeling complexes by phosphorylation.From1 Sep 2012 → 20 Dec 2019Funding: FWO fellowships
- A MultiMarker Methylation Signature for the diagnosis and prognosis of cancer.From1 Apr 2012 → 31 Mar 2015Funding: IOF - Industrial Research Fund
- Explorative and therapeutic targeting of protein phosphatase PP1 holoenzymes.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project
- Signaling by protein kinase Melk in multipotent progenitors, astrocytes and malignant astrocytoma.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project
Publications
1 - 10 of 35
- Substrate mapping and activity regulation of PP1 holoenzymes(2022)
Authors: Dan Wu, Mathieu Bollen, Aleyde Van Eynde
- Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases(2021)
Authors: Mathieu Bollen, Aleyde Van Eynde
- Enhanced DNA-repair capacity and resistance to chemically induced carcinogenesis upon deletion of the phosphatase regulator NIPP1(2020)
Authors: Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
- The phosphatase regulator NIPP1 restrains chemokine-driven skin inflammation.(2020)
Authors: Iris Verbinnen, Marloes Jonkhout, Kathelijne Szekér, Margareta Nikolic, Susan Schlenner, Aleyde Van Eynde, Mathieu Bollen
Pages: 1576 - 1588 - The phosphatase regulator NIPP1 restrains chemokine-driven inflammation and DNA-damage repair in the skin(2019)
Authors: Iris Verbinnen, Mathieu Bollen, Aleyde Van Eynde
- Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics.(2019)
Authors: Monique Beullens, Mathieu Bollen, Aleyde Van Eynde
Pages: 16 - 30 - MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells (vol 35, e00267, 2015)(2018)
Authors: Lijs Beke, Cenk Kig, Joannes TM Linders, Shannah Boens, An Boeckx, Erika van Heerde, Marc Parade, An De Bondt, Ilse Van den Wyngaert, Tarig Bashir, et al.
- The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2(2018)
Authors: Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
Pages: 18031 - 18039 - A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions(2018)
Authors: Dan Wu, Rita Derua, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
Pages: 15152 - 15162 - Overexpression of PP1-NIPP1 limits the capacity of cells to repair DNA double-strand breaks(2018)
Authors: Dan Wu, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen