Researcher
Frank Peelman
- Disciplines:Palliative care and end-of-life care, Laboratory medicine, Other translational sciences, Regenerative medicine, Nursing, Other clinical sciences, Other basic sciences, Other paramedical sciences, Other health sciences, Other medical and health sciences
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Biochemistry (Department)
Member
From1 Oct 1994 → 30 Sep 2018
Projects
1 - 6 of 6
- In-depth study of structure/activity relations of the glucocorticoid receptor and its ligands via an extreme mutation scanFrom1 Nov 2023 → TodayFunding: BOF - doctoral mandates
- Prepared for SARS-CoV-3: advancing our understanding of SARS coronavirus antigenic and pathogenic evolutionFrom1 Jan 2022 → TodayFunding: FWO EOS
- A bioinformatic toolbox for the analysis and optimization of a high-throughput deep mutational scanning assay: development and case-studyFrom1 Nov 2020 → TodayFunding: FWO fellowships
- In-depth study of structure/activity relations of the glucocorticoid receptor and its ligands via an extreme mutation scan.From1 Nov 2019 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant
- Development of a robust expression system for stable soluble influenza neuraminidaseFrom1 Nov 2019 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant
- Bioinformatics for a high-throughput deep mutational scanning protein-protein interaction assay: turning a prototype into a precision medicine toolboxFrom1 Oct 2019 → 31 Oct 2020Funding: BOF - doctoral mandates
Publications
1 - 10 of 11
- Deep mutational scanning of proteins in mammalian cells(2023)
Authors: Stefanie Maes, Nick Deploey, Frank Peelman, Sven Eyckerman
- The biologist’s guide to the glucocorticoid receptor’s structure(2023)
Authors: Nick Deploey, Laura Van Moortel, Inez Rogatsky, Frank Peelman, Karolien De Bosscher
- Biallelic loss-of-function variants in RAX2, encoding a homeobox-containing Rax transcription factor, cause autosomal recessive inherited retinal disease(2018)
Authors: Stijn Van de Sompele, Claire Smith, Marianthi Karali, Marta Corton, Kristof Van Schil, Frank Peelman, Timothy Cherry, Toon Rosseel, Hannah Verdin, Julien Derolez, et al.
Number of pages: 1 - RNF41 interacts with the VPS52 subunit of the GARP and EARP complexes(2017)
Authors: Delphine Masschaele, Leentje De Ceuninck, Joris Wauman, Dieter Defever, Frank Stenner, Samuel Lievens, Frank Peelman, Jan Tavernier
- High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in The Netherlands: identification and characterization of eight novel mutations(2011)
Authors: Adriaan G Holleboom, Jan A Kuivenhoven, Frank Peelman, Alinda W Schimmel, Jorge Peter, Joep C Defesche, John JP Kastelein, G Kees Hovingh, Erik S Stroes, Mohammad Mahdi Motazacker
Pages: 1290 - 1298 - Chylomicronemia with low Postheparin Lipoprotein Lipase levels in the setting of GPIHBP1 defects(2010)
Authors: Remco Franssen, Stephen G Young, Frank Peelman, Jozef Hertecant, Jeroen A Sierts, Alida WM Schimmel, Andre Bensadoun, John JP Kastelein, Loren G Fong, Geesje M Dallinga-Thie, et al.
Pages: 169 - 178 - Abnormal LPL release leads to chylomicronemia in the presence of GPIHBP1 defects(2010)Volume: 11
Authors: BJ Arsenault, AP Beigneux, Frank Peelman, R Franssen, J Hertecant, SG Young, GM Dallinga-Thie
Pages: 88 - 88 - The metabolism of triglyceride-rich lipoproteins revisited: new players, new insight(2010)
Authors: Geesje M Dallinga-Thie, Remco Franssen, Hans L Mooij, Maartje E Visser, H Carlijne Hassing, Frank Peelman, John JP Kastelein, Miklos Peterfy, Max Nieuwdorp
Pages: 1 - 8 - Functional characterization of naturally occurring pathogenic mutations in the human leptin receptor(2008)
Authors: Wendy Kimber, Frank Peelman, Xavier Prieur, Theresia Wangensteen, Stephen O'Rahilly, Jan Tavernier, I. Sadaf Farooq
Pages: 6043 - 6052 - Multiple roles for the SOCS box(2008)Volume: 43
Authors: Julie Piessevaux, Delphine Lavens, Frank Peelman, Jan Tavernier
Pages: 293 - 293
Patents
1 - 10 of 10
- TARGETED MUTANT INTERFERON-GAMMA AND USES THEREOF (Inventor)
- TARGETED MUTANT INTERFERON-GAMMA AND USES THEREOF (Inventor)
- NOVEL TSLP INHIBITORS (Inventor)
- TARGETED MUTANT INTERFERON-β USES THEREOF (Inventor)
- TARGETING OF CYTOKINE ANTAGONISTS (Inventor)
- TARGETED MODIFIED IL-1 FAMILY MEMBERS (Inventor)
- TARGETED MODIFIED TNF FAMILY MEMBERS (Inventor)
- TARGETED MUTANT INTERFERON-GAMMA AND USES THEREOF (Inventor)
- TARGETED MODIFIED IL-1 FAMILY MEMBERS (Inventor)
- TARGETED MODIFIED TNF FAMILY MEMBERS (Inventor)