Researcher
Sven Eyckerman
- Keywords (Ghent University):protein complexes
- Disciplines (Flanders Institute for Biotechnology):Analytical biochemistry, Cell death and senescence, Analysis of next-generation sequence data, General diagnostics
- Disciplines (Ghent University):Transcription and translation, Cell signalling, Biomarker discovery, In vitro testing, Cancer biology
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Eyckerman Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Biochemistry (Department)
Member
From1 Oct 1998 → 30 Sep 2018
Projects
1 - 5 of 5
- Functional study of a novel, long non-coding RNA (lncRNA) upstream of ABCA4 in retina and blindnessFrom1 Nov 2022 → TodayFunding: BOF - doctoral mandates
- Replication fork protector dependency factors: novel targets for combination treatment and immunomodulation in neuroblastoma (REINFORCE)From1 Jan 2022 → TodayFunding: BOF - projects
- The role of super-enhancer regulated SOX11 in regulation of SWI/SNF and PRC2 activity in adrenergic neuroblastomaFrom1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Large scale microfluidics-based optimization of synthetic biology_x000D_ circuits and cell reprogrammingFrom1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
- Long noncoding RNAs in cancer: deciphering the functional role of the dark matter of the human cancer genomeFrom1 Jan 2016 → 31 Dec 2022Funding: BOF - Concerted Research Project from 1994
Publications
1 - 10 of 19
- Cornification of keratinocytes is associated with differential changes in the catalytic activity and the immunoreactivity of transglutaminase-1(2023)
Authors: Marta Surbek, Tessa Van de Steene, Attila Placido Sachslehner, Bahar Golabi, Johannes Griss, Sven Eyckerman, Kris Gevaert, Leopold Eckhart
- Deep mutational scanning of proteins in mammalian cells(2023)
Authors: Stefanie Maes, Nick Deploey, Frank Peelman, Sven Eyckerman
- A decoupled Virotrap approach to study the interactomes of N-terminal proteoforms(2023)Series: Modifications and targeting of protein termini : part A
Authors: Annelies Bogaert, Tessa Van de Steene, Marnik Vuylsteke, Sven Eyckerman, Kris Gevaert, Thomas Arnesen
Pages: 253 - 287 - N-terminal proteoforms may engage in different protein complexes(2023)
Authors: Annelies Bogaert, Daria Fijalkowska, An Staes, Tessa Van de Steene, Marnik Vuylsteke, Charlotte Stadler, Sven Eyckerman, Kerstin Spirohn, Tong Hao, Michael A Calderwood, et al.
- Orthogonal proteomics methods to unravel the HOTAIR interactome(2022)
Authors: Louis Delhaye, Edith De Bruycker, Pieter-Jan Volders, Daria Fijalkowska, Delphine De Sutter, Sven Degroeve, Lennart Martens, Pieter Mestdagh, Sven Eyckerman
- RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition(2022)
Authors: Carolina de Carvalho Nunes, Lisa Depestel, Liselot Mus, Kaylee M. Keller, Louis Delhaye, Amber Louwagie, Muhammad Rishfi, Alex Whale, Neesha Kara, Simon R. Andrews, et al.
- Proteome profiling of RNF213 depleted cells reveals nitric oxide regulator DDAH1 antilisterial activity(2021)
Authors: Lia Martina, Caroline Asselman, Fabien Henri Thery, Katie Boucher, Louis Delhaye, Teresa Maia, Bart Dermaut, Sven Eyckerman, Francis Impens
- Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity(2021)
Authors: Fabien Henri Thery, Lia Martina, Caroline Asselman, Heidi Repo, Y Zhang, Koen Sedeyn, Georgios Moschonas, C Bredow, QW Teo, J Zhang, et al.
- Capturing salmonella SspH2 host targets in virus-like particles(2021)
Authors: Margaux De Meyer, Igor Fijalkowski, Veronique Jonckheere, Delphine De Sutter, Sven Eyckerman, Petra Van Damme
- IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress(2020)
Authors: Michael J. Grey, Eva Cloots, Mariska S. Simpson, Nicole LeDuc, Yevgeniy V. Serebrenik, Heidi De Luca, Delphine De Sutter, Phi Luong, Jay R. Thiagarajah, Adrienne W. Paton, et al.
Patents
1 - 9 of 9
- Improved aminopeptidases for single molecule peptide sequencing (Inventor)
- Means and methods for single molecule peptide sequencing (Inventor)
- Means and methods for single molecule peptide sequencing (Inventor)
- Usages of recombinant extracellular vesicles (Inventor)
- Viral particle based protein-protein interaction trap (Inventor)
- VIRAL PARTICLE BASED SMALL MOLECULE-PROTEIN INTERACTION TRAP (Inventor)
- Usages of recombinant extracellular vesicles (Inventor)
- Means and methods for single molecule peptide sequencing (Inventor)
- Universal MRM tags for protein quantification (Inventor)