Researcher
Thijs Van de Vyver
- Disciplines:Medicinal products, Pharmacognosy and phytochemistry, Pharmaceutics, Biomarker discovery and evaluation, Other pharmaceutical sciences, Drug discovery and development, Toxicology and toxinology, Pharmacotherapy, Pharmacology
Affiliations
- Department of Pharmaceutics (Department)
Member
From18 Aug 2016 → 26 Sep 2021
Projects
1 - 1 of 1
- Repurposing of cationic amphiphilic drugs as adjuvants to enhance
the cellular delivery of small interfering RNAFrom1 Oct 2016 → 30 Sep 2020Funding: FWO fellowships
Publications
1 - 8 of 8
- The alpha-adrenergic antagonist prazosin promotes cytosolic siRNA delivery from lysosomal compartments(2023)
Authors: Thijs Van de Vyver, Cristina Muntean, Iuliia Efimova, Dmitri Krysko, Lynn De Backer, Stefaan De Smedt, Koen Raemdonck
Pages: 142 - 158 - Modulating intracellular pathways to improve non-viral delivery of RNA therapeutics(2022)
Authors: Thijs Van de Vyver, Koen Raemdonck
- Old drugs with new tricks : repurposing small molecules to promote lysosomal escape of small nucleic acid therapeutics(2021)
Authors: Thijs Van de Vyver
- Surfactant protein B promotes cytosolic SiRNA delivery by adopting a virus-like mechanism of action(2021)
Authors: Roberta Guagliardo, Lore Herman, Jelle Penders, Agata Zamborlin, Herlinde De Keersmaecker, Thijs Van de Vyver, Sandrine Verstraeten, Pieterjan Merckx, Marie-Paule Mingeot-Leclercq, Mercedes Echaide, et al.
Pages: 8095 - 8109 - Hydrogel-induced cell membrane disruptions enable direct cytosolic delivery of membrane-impermeable cargo(2021)
Authors: Jelter Van Hoeck, Thijs Van de Vyver, Aranit Harizaj, Glenn Goetgeluk, Pieterjan Merckx, Jing Liu, Mike Wels, FĂ©lix Sauvage, Herlinde De Keersmaecker, Christian Vanhove, et al.
- Cationic amphiphilic drugs boost the lysosomal escape of small nucleic acid therapeutics in a nanocarrier-dependent manner(2020)
Authors: Thijs Van de Vyver, Bram Bogaert, Lynn De Backer, Freya Joris, Roberta Guagliardo, Jelter Van Hoeck, Pieterjan Merckx, Srinivas Ramishetti, Dan Peer, Katrien Remaut, et al.
Pages: 4774 - 4791 - Repurposing cationic amphiphilic drugs as adjuvants to induce lysosomal siRNA escape in nanogel transfected cells(2018)
Authors: Freya Joris, Lynn De Backer, Thijs Van de Vyver, Chiara Bastiancich, Koen Raemdonck
Pages: 266 - 276 - Glycation in human fingernail clippings using ATR-FTIR spectrometry, a new marker for the diagnosis and monitoring of diabetes mellitus(2017)
Authors: Renaat Coopman, Thijs Van de Vyver, Antoine Sadiki Kishabongo, Philippe Katchunga, Elisabeth H Van Aken, Justin Cikomola, Tinne Monteyne, Marijn Speeckaert
Pages: 62 - 67