Researcher
Tim Van de Walle
- Disciplines:Transport phenomena, Other chemical sciences, Separation and membrane technologies, Process engineering, General chemical and biochemical engineering, Chemical product design and formulation, Catalysis and reacting systems engineering, Other (bio)chemical engineering, Organic chemical synthesis, Agricultural plant production, Bio-organic chemistry
Affiliations
- Department of Green Chemistry and Technology (Department)
Member
From1 Jan 2018 → 26 Sep 2021 - Department of Sustainable Organic Chemistry and Technology (Department)
Member
From1 Oct 2016 → 31 Dec 2017
Projects
1 - 1 of 1
- Explorations in quinoline chemistry – towards the development of novel piperidine-quinoline hybrids with antimalarial activity and nitroxoline analogs with anti-tumor activityFrom1 Oct 2016 → 30 Sep 2020Funding: BOF - Doctoral projects
Publications
1 - 9 of 9
- Synthesis of novel nitroxoline analogs with potent cathepsin B exopeptidase inhibitory activity(2020)
Authors: Tim Van de Walle, Marina Briand, Ana Mitrovic, Izidor Sosic, Stanislav Gobec, Janko Kos, Leentje Persoons, Dirk Daelemans, Steven De Jonghe, Zorica Ubiparip, et al.
Pages: 2477 - 2490 - Development of antimalarial quinoline-based conjugates and anticancer nitroxoline derivatives(2020)
Authors: Tim Van de Walle
- Design and synthesis of novel ferrocene-quinoline conjugates and evaluation of their electrochemical and antiplasmodium properties(2020)
Authors: Aleksandra Minić, Tim Van de Walle, Kristof Van Hecke, Jill Combrinck, Peter J. Smith, Kelly Chibale, Matthias D'hooghe
- Synthesis of 1,4U+2010thiazepaneU+2010based curcuminoids with promising anticancer activity(2019)
Authors: Tim Van de Walle, Kristof Van Hecke, Charlotte Grootaert, Matthias D'hooghe
Pages: 12583 - 12600 - Synthesis of nonU+2010symmetrical nitrogenU+2010containing curcuminoids in the pursuit of new anticancer candidates(2019)
Authors: Tim Van de Walle, Charlotte Grootaert, Kristof Van Hecke, Nathalie Catry, Matthias D'hooghe
Pages: 236 - 247 - Synthesis and cytotoxic evaluation of monocarbonyl curcuminoids and their pyrazoline derivatives(2019)
Authors: Tim Van de Walle, Charlotte Grootaert, Steven De Jonghe, Leentje Persoons, Dirk Daelemans, Kristof Van Hecke, Matthias D'hooghe
Pages: 2045 - 2051 - Synthesis of Novel AzaU+2010aromatic Curcuminoids with Improved Biological Activities towards Various Cancer Cell Lines(2018)
Authors: Tim Van de Walle, Charlotte Grootaert, Margot Bultinck, Matthias D'hooghe
Pages: 381 - 392 - Synthesis and biological evaluation of novel quinoline-piperidine scaffolds as antiplasmodium agents
Authors: Tim Van de Walle, Maya Boone, Julie Van Puyvelde, Jill Combrinck, Peter J. Smith, Kelly Chibale, Matthias D'hooghe
- Recent contributions of quinolines to antimalarial and anticancer drug discovery research
Authors: Tim Van de Walle, Lore Cools, Matthias D'hooghe