Researcher
Koen Raemdonck
- Disciplines:Nanobiotechnology, Environmental safety and health of nanotechnology, Nanoscale characterisation, Nanophotonics, Nanotechnology not elsewhere classified, Nanometrology, Drug discovery and development not elsewhere classified, Clinical trials, Other pharmaceutical sciences not elsewhere classified, Compound screening, In vitro testing, Biopharmaceuticals, Non-clinical studies, Molecular medicine, Vaccines, Nanomaterials, Nanomanufacturing, Nanofabrication, growth and self assembly, Nanoelectromechanical systems
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2004 → Today
Infrastructure
1 - 1 of 1
- Confocal and two-photon Microscope (Consortium partner)
Projects
1 - 10 of 18
- Exploring co-encapsulation of antihistamines and immune checkpoint siRNAs in lipid nanoparticles for cancer immunotherapy.From1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Conformationally locked G4-decoy oligonucleotides for selective telomerase inhibition and development of a nucleic acid-based anti-telomerase PROTAC strategyFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Synthesis of modified PNA probes for sequence-selective G-quadruplex photoalkylation.From1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- REpurposing lung Surfactant Protein B for Inhalation therapy with RNA therapeuticsFrom1 May 2021 → TodayFunding: H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
- Repurposing lung surfactant protein B for inhalation therapy with RNA therapeuticsFrom1 Nov 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciencesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- NANOMED / Colloidally stable nanogel formulations for siRNA deliveryFrom1 Aug 2019 → 31 Jan 2020Funding: BOF - doctoral mandates
- Local immunomodulation of atherosclerosis by CD8+ T-cell based nanomedicinesFrom1 May 2019 → 30 Apr 2022Funding: FWO research project (including WEAVE projects)
- RNA-MAGIC: RNA-based bioMArkers and tarGets In asthma and Chronic Obstructive Pulmonary Disease (COPD)From1 Jan 2019 → TodayFunding: BOF - projects
- Combination cancer therapy by simultaneous delivery of cationic amphiphilic drugs and RNA therapeutics using a polymer delivery platformFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 87
- Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics(2024)
Authors: Jana Ramon, Yanou Engelen, Herlinde De Keersmaecker, Ilia Goemaere, Deep Punj, Julián Mejía Morales, Cédric Bonte, Geert Berx, Esther Hoste, Stephan Stremersch, et al.
Pages: 1019 - 1036 - Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer(2023)
Authors: Cristina Muntean, Eva Blondeel, Laure Harinck, Kunal Pednekar, Jai Prakash, Olivier De Wever, Jeanne Leblond Chain, Stefaan De Smedt, Katrien Remaut, Koen Raemdonck
- The alpha-adrenergic antagonist prazosin promotes cytosolic siRNA delivery from lysosomal compartments(2023)
Authors: Thijs Van de Vyver, Cristina Muntean, Iuliia Efimova, Dmitri Krysko, Lynn De Backer, Stefaan De Smedt, Koen Raemdonck
Pages: 142 - 158 - Capric acid and myristic acid permeability enhancers in curved liposome membranes(2023)
Authors: Samaneh Davoudi, Koen Raemdonck, Kevin Braeckmans, An Ghysels
Pages: 6789 - 6806 - Modulating intracellular pathways to improve non-viral delivery of RNA therapeutics(2022)
Authors: Thijs Van de Vyver, Koen Raemdonck
- Non-invasive cell-tracking methods for adoptive T cell therapies(2022)
Authors: Jelter Van Hoeck, Christian Vanhove, Koen Raemdonck
Pages: 793 - 807 - Plasma membrane perforation by GSDME during apoptosis-driven secondary necrosis(2022)
Authors: Elke De Schutter, Jana Ramon, Benjamin Pfeuty, Stephan Stremersch, Koen Raemdonck, Ken Op de Beeck, Franck Riquet, Kevin Braeckmans, Peter Vandenabeele
- Non-viral siRNA delivery to T cells : challenges and opportunities in cancer immunotherapy(2022)
Authors: Jelter Van Hoeck, Kevin Braeckmans, Stefaan De Smedt, Koen Raemdonck
- A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs(2022)
Authors: Bram Bogaert, Felix Sauvage, Roberta Guagliardo, Cristina Muntean, [missing] Van Phuc Nguyen, Eline Pottie, Mike Wels, An-Katrien Minnaert, Qiangbing Yang, Dan Peer, et al.
Pages: 256 - 270 - Challenges and strategies for the delivery of biologics to the cornea(2021)
Authors: Mike Wels, D. Roels, Koen Raemdonck, Félix Sauvage
Pages: 560 - 578
Patents
1 - 7 of 7
- MOLECULAR ADJUVANTS FOR ENHANCED CYTOSOLIC DELIVERY OF ACTIVE AGENTS (Inventor)
- PARTICLES COMPRISING SURFACTANT PROTEIN B AND ONE OR MORE LIPIDS (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- PARTICLES COMPRISING SURFACTANT PROTEIN B AND ONE OR MORE LIPIDS (Inventor)
- MOLECULAR ADJUVANTS FOR ENHANCED CYTOSOLIC DELIVERY OF ACTIVE AGENTS (Inventor)
- PARTICLES COMPRISING SURFACTANT PROTEIN B AND ONE OR MORE LIPIDS (Inventor)