Researcher
Delfien Syx
- Disciplines:Paediatrics and neonatology, Palliative care and end-of-life care, Laboratory medicine, Other translational sciences, Molecular and cell biology, Regenerative medicine, Nursing, Other clinical sciences, Other basic sciences, Other paramedical sciences, Other health sciences, Other medical and health sciences, Systems biology, Genetics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → 31 Mar 2024 - Department of Pediatrics and medical genetics (Department)
Member
From1 Sep 2008 → 30 Sep 2018
Projects
1 - 5 of 5
- Zebrafish as a model to study pain in Ehlers-Danlos syndromesFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Understanding human linkeropathies: study of the phenotypic and molecular consequences of defective biosynthesis of the glycosaminoglycan tetrasaccharide linker region.From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- An integrated translational platform to improve the management and outcome of rare heritable connective tissue diseaseFrom1 Jan 2021 → TodayFunding: BOF - projects
- Identifying a pain signature in classical Ehlers-Danlos syndromeFrom1 Nov 2020 → 30 Sep 2023Funding: FWO fellowships
- Study of mediators and pathways contributing to chronic pain in Ehlers-Danlos syndrome From1 Oct 2016 → 30 Sep 2019Funding: BOF - Other initiatives
Publications
1 - 10 of 19
- The establishment of the first reported zebrafish model for thoracic aortic dissection and rupture(2023)
Authors: Michiel Vanhooydonck, Maxim Verlee, Lore Pottie, Annekatrien Boel, Piyanoot Tapaneeyaphan, Marta Guerreiro Santana Ramos Da Silva, Adelbert De Clercq, Lisa Caboor, Matthias Van Impe, Delfien Syx, et al.
Number of pages: 1 - The establishment of the first reported zebrafish model for thoracic aortic dissection and rupture(2023)
Authors: Michiel Vanhooydonck, Lore Pottie, Annekatrien Boel, Piyanoot Tapaneeyaphan, Marta Guerreiro Santana Ramos Da Silva, Adelbert De Clercq, Matthias Van Impe, Delfien Syx, Andy Willaert, Lisa Caboor, et al.
Number of pages: 1 - The establishment of the first reported zebrafish model for thoracic aortic dissection and rupture(2023)
Authors: Michiel Vanhooydonck, Maxim Verlee, Lore Pottie, Annekatrien Boel, Piyanoot Tapaneeyaphan, Marta Guerreiro Santana Ramos Da Silva, Adelbert De Clercq, Lisa Caboor, Matthias Van Impe, Delfien Syx, et al.
Number of pages: 1 - The Ehlers–Danlos syndromes against the backdrop of inborn errors of metabolism(2022)
Authors: Tim Van Damme, Marlies Colman, Delfien Syx, Fransiska Malfait
- A tapt1 knockout zebrafish line with aberrant lens development and impaired vision models human pediatric cataract(2022)
Authors: Tamara Jarayseh, Brecht Guillemyn, Hanna De Saffel, Jan Willem Bek, Sujatha Jagadeesh, Sofie Symoens, Fransiska Malfait, Delfien Syx, Filip Van Nieuwerburgh, Yannick Gansemans, et al.
Number of pages: 1 - Collagens in the physiopathology of the Ehlers–Danlos Syndromes(2021)Series: Biology of Extracellular Matrix
Authors: Fransiska Malfait, Robin Vroman, Marlies Colman, Delfien Syx, Florence Ruggiero
Pages: 55 - 119 - Aberrant binding of mutant HSP47 affects posttranslational modification of type I collagen and leads to osteogenesis imperfecta(2021)
Authors: Delfien Syx, Yoshihiro Ishikawa, Jan Gebauer, Sergei P. Boudko, Brecht Guillemyn, Tim Van Damme, Sanne D'hondt, Sofie Symoens, Sheela Nampoothiri, Douglas B. Gould, et al.
- Loss of TANGO1 leads to absence of bone mineralization(2021)
Authors: Brecht Guillemyn, Sheela Nampoothiri, Delfien Syx, Fransiska Malfait, Sofie Symoens
- Caffey disease is associated with distinct arginine to cysteine substitutions in the proα1(I) chain of type I procollagen(2021)
Authors: Tibbe Dhooge, Delfien Syx, Trinh Hermanns-Lê, Ingrid Hausser, Geert Mortier, Jonathan Zonana, Sofie Symoens, Peter H. Byers, Fransiska Malfait
Pages: 2378 - 2385 - Animal models of Ehlers–Danlos syndromes : phenotype, pathogenesis, and translational potential(2021)
Authors: Robin Vroman, Anne-Marie Malfait, Rachel Miller, Fransiska Malfait, Delfien Syx