Researcher
Inna Afonina
- Keywords (Ghent University):NF-kB signaling in inflammation and cancer
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Cell signalling, Inflammation, Cancer biology
Affiliations
- Beyaert Lab (Research group)
Member
From1 Jan 2017 → Today - Department of Biomedical molecular biology (Department)
Member
From1 May 2013 → Today
Projects
1 - 5 of 5
- Role of linear ubiquitination in intestinal inflammation and diseaseFrom1 Nov 2023 → TodayFunding: FWO fellowships
- A novel role for CARD14 in prostate cancerFrom1 Oct 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Characterisation of the physiological function of CARD14 in the context of psoriasisFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- CARD14/MALT1 signaling in keratinocytes: from molecular
characterisation to validation as therapeutic targetFrom1 Jan 2017 → 31 Mar 2021Funding: FWO Strategic Basic Research Grant
- Characterisation of the biochemical and physiological function of CARMA2 in the context of psoriasisFrom1 Oct 2013 → 31 Jan 2020Funding: FWO fellowships, BOF - Other initiatives
Publications
1 - 10 of 28
- IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer(2023)
Authors: Olga S. Blomberg, Lorenzo Spagnuolo, Hannah Garner, Leonie Voorwerk, Olga I. Isaeva, Ewald van Dyk, Noor Bakker, Myriam Chalabi, Chris Klaver, Maxime Duijst, et al.
Pages: 106 - 123.e10 - A20 is a master switch of IL-33 signalling in macrophages and determines IL-33-induced lung immunity(2023)
Authors: Aurora Holgado Muñoz, Zhuangzhuang Liu, Aigerim Aidarova, Christina Müller, Mira Haegman, Yasmine Driege, Marja Kreike, Charlotte Scott, Inna Afonina, Rudi Beyaert
Pages: 244 - 256.e4 - Infection and immunity : 'There Are Things Out There You (Don't) Need To Know About'(2022)
Authors: Inna Afonina, Eik Hoffmann
Pages: 3920 - 3925 - Editorial: Post-translational modifications of extracellular signaling molecules and antigens in immune and inflammatory responses(2022)
Authors: Inna Afonina, Loredana Frasca, Gaby Palmer
- CARD14 signalling ensures cell survival and cancer associated gene expression in prostate cancer cells(2022)
Authors: Domien Vanneste, Yasmine Driege, Marieke Carels, Elien Van Nuffel, Pieter De Bleser, Yvan Saeys, Rudi Beyaert, Inna Afonina
- Immune responses and therapeutic options in psoriasis(2021)
Authors: Inna Afonina, Elien Van Nuffel, Rudi Beyaert
Pages: 2709 - 2727 - IL-33trap-mediated IL-33 neutralization does not exacerbate choroidal neovascularization, but fails to protect against retinal degeneration in a dry age-related macular degeneration model(2021)
Authors: Inge Van Hove, Tine Van Bergen, Isabelle Etienne, Aurora Holgado Muñoz, Inna Afonina, Rudi Beyaert, Jean HM. Feyen, Tjing-Tjing Hu
- Defining the combinatorial space of PKC::CARD-CC signal transduction nodes(2021)
Authors: Yasmine Driege, Marja Kreike, Styliani Iliaki, Domien Vanneste, Marie Lork, Inna Afonina, Harald Braun, Rudi Beyaert
Pages: 1630 - 1647 - Polo-like kinase 1 (PLK1) signaling in cancer and beyond(2021)
Authors: Styliani Iliaki, Rudi Beyaert, Inna Afonina
- MALT1 targeting suppresses CARD14‐induced psoriatic dermatitis in mice(2020)
Authors: Elien Van Nuffel, Jens Staal, Griet Baudelet, Mira Haegman, Yasmine Driege, Tino Hochepied, Inna Afonina, Rudi Beyaert