Researcher
Jonas Janssens
- Disciplines:Medicinal chemistry not elsewhere classified, Organic chemical synthesis, Biomolecular modelling and design, Medicinal and biomolecular chemistry not elsewhere classified, Medicinal chemistry, Bio-organic chemistry, Molecular medicine, Structural biology
Affiliations
- Department of Organic and Macromolecular Chemistry (Department)
Member
From1 Oct 2014 → 22 Sep 2019
Projects
1 - 1 of 1
- Synthesis of triazole analogues of Peloruside A via “click”-chemistry as potential antitumor compounds.From1 Nov 2014 → 31 Oct 2018Funding: BOF - Doctoral projects
Publications
1 - 10 of 12
- Radiosynthesis, in vitro and preliminary biological evaluation of [F-18]2-amino-4-((2-((3-fluorobenzyl)oxy)benzyl)(2-((3-(fluoromethyl)benzyl)oxy)benzyl)amino) butanoic acid, a novel alanine serine cysteine transporter 2 inhibitor-based positron emission tomography tracer(2020)
Authors: Tristan Baguet, Jakob Bouton, Jonas Janssens, Glenn Pauwelyn, Jeroen Verhoeven, Benedicte Descamps, Christian Vanhove, Filip De Vos
Pages: 442 - 455 - Broadening the message : a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells(2019)
Authors: Rein Verbeke, Ine Lentacker, Karine Breckpot, Jonas Janssens, Serge Van Calenbergh, Stefaan De Smedt, Heleen Dewitte
Pages: 1655 - 1669 - Ceramide-templated macrolactams : total synthesis and biological evaluation of macrocyclic α-galactosylceramide analogues and their aglycons(2019)
Authors: Jonas Janssens, Johan Van der Eycken, Serge Van Calenbergh
Pages: 2253 - 2267 - α-Galactosylceramide analogues as iNKT-cell antigens : synthesis, biological evaluation and structural analysis(2019)
Authors: Jonas Janssens
- A molecular switch in mouse CD1d modulates natural killer T cell activation by α-galactosylsphingamides(2019)
Authors: Jing Wang, Joren Guillaume, Jonas Janssens, Soumya G. Remesh, Ge Ying, Aruna Bitra, Dirk Zajonc
Pages: 14345 - 14356 - 4''-O-Alkylated α-galactosylceramide analogues as iNKT-cell antigens : synthetic, biological, and structural studies(2019)
Authors: Jonas Janssens, Aruna Bitra, Jing Wang, Tine Decruy, Koen Venken, Johan Van der Eycken, Dirk Elewaut, Dirk Zajonc, Serge Van Calenbergh
Pages: 147 - 168 - Galactosylsphingamides : new α-GalCer analogues to probe the F’-pocket of CD1d(2017)
Authors: Joren Guillaume, Jing Wang, Jonas Janssens, Soumya G Remesh, Martijn Risseeuw, Tine Decruy, Mathy Froeyen, Dirk M Zajonc
- Efficient divergent synthesis of new immunostimulant 4″-modified α-galactosylceramide analogues(2017)
Authors: Jonas Janssens, Tine Decruy, Toshiyuki Seki, Simon Krols, Johan Van der Eycken, Moriya Tsuji
Pages: 642 - 647 - A practical approach to the synthesis of new 4U+201D-modified U+03B1-galactosylceramide analogues
Authors: Jonas Janssens, Johan Van der Eycken
Pages: 52 - 52 - Regioselective ring opening of 1,3-dioxane-type acetals in carbohydrates
Authors: Jonas Janssens, Martijn Risseeuw, Johan Van der Eycken
Pages: 6405 - 6431