Researcher
Steven Strubbe
- Keywords:Immunology, molecular biology
- Disciplines:Adaptive immunology, Immunogenetics, Stem cell biology, Hematology
Affiliations
- Department of Diagnostic Sciences (Department)
Member
From1 Oct 2018 → 25 Sep 2022 - Department of Clinical chemistry, microbiology and immunology (Department)
Member
From1 Sep 2015 → 30 Sep 2018
Projects
1 - 1 of 1
- Gene-targeting of human pluripotent stem cells to study human T lymphocyte development and immune deficienciesFrom1 Jan 2016 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 10
- Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development(2022)
Authors: Juliette Roels, Jolien Van Hulle, Marieke Lavaert, Anna Kuchmiy, Steven Strubbe, Tom Putteman, Bart Vandekerckhove, Georges Leclercq, Filip Van Nieuwerburgh, Lena Böhme, et al.
- In vitro model systems to study human T cell development(2022)Edition: 2Series: Methods in Molecular Biology (MIMB)
Authors: Nina Lambrechts, Kai Ling Liang, Imke Velghe, Steven Strubbe, Anne-Catherine Dolens, Tom Taghon, Remy Bosselut, Melanie S. Vacchio
Pages: 335 - 354 - In vitro modeling of SCID using primary patient cells(2021)
Authors: Steven Strubbe
- Modeling of human T cell development in vitro as a read-out for hematopoietic stem cell multipotency(2021)
Authors: Steven Strubbe, Tom Taghon
Pages: 2113 - 2122 - A tumor suppressor enhancer of PTEN in T-cell development and leukemia(2021)
Authors: L Tottone, O Lancho, JW Loh, A Singh, S Kimura, Anna Kuchmiy, Steven Strubbe, MA Lawlor, V da Silva-Diz, S Luo, et al.
Pages: 93 - 109 - A novel non-coding variant in DCLRE1C results in deregulated splicing and induces SCID through the generation of a truncated ARTEMIS protein that fails to support V(D)J recombination and DNA damage repair(2021)
Authors: Steven Strubbe, Marieke De Bruyne, Ulrich Pannicke, Elien Beyls, Bart Vandekerckhove, Georges Leclercq, Elfride De Baere, Victoria Bordon, Anne Vral, Klaus Schwarz, et al.
- Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia(2020)
Authors: Morgan Thénoz, B Szarzynska, M Landfors, Anna Kuchmiy, Steven Strubbe, Lindy Reunes, Filip Matthijssens, Wouter Van Loocke, B Erarslan-Uysal, P Richter-Pechanska, et al.
Pages: 274 - 289 - Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia(2020)Volume: 136
Authors: Morgan Thénoz, Bronislawa Szarzynska, Mattias Landfors, Anna Kuchmiy, Steven Strubbe, Lindy Reunes, Filip Matthijssens, Wouter Van Loocke, Marc R. Mansour, Utpal Dave, et al.
Number of pages: 1 - Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development(2020)
Authors: Anna Kuchmiy, Matthias De Decker, Steven Strubbe, Marieke Lavaert, Georges Leclercq, Filip Van Nieuwerburgh, Pieter Van Vlierberghe, Tom Taghon
Pages: 1280 - 1292 - PHF6 expression levels impact human hematopoietic stem cell differentiation(2020)
Authors: Anne-Catherine Dolens, Steven Strubbe, Inge Van de Walle, Finola E. Moore, Suzanne Vanhauwaert, Filip Matthijssens, David M. Langenau, Pieter Van Vlierberghe, Tom Taghon