Researcher
Tom Van Nieuwenhuysen
- Disciplines:Biophysics, Molecular and cell biology, Laboratory medicine, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From1 Jan 2011 → 24 Sep 2017
Projects
1 - 1 of 1
- Characterization of novel target genes of the Wnt signaling pathway relevant to intestinal cancers.From1 Oct 2011 → 30 Jun 2016Funding: IWT personal funding - specialisation scholarships
Publications
1 - 10 of 11
- Engraftment of allotransplanted tumor cells in adult rag2 mutant Xenopus tropicalis(2022)
Authors: Dieter Tulkens, Dionysia Dimitrakopoulou, Marthe Boelens, Tom Van Nieuwenhuysen, Suzan Demuynck, Wendy Toussaint, Pieter Van Vlierberghe, Kris Vleminckx
- CRISPR-SID : identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping(2021)
Authors: Thomas Naert, Dieter Tulkens, Tom Van Nieuwenhuysen, Joanna Przybyl, Suzan Demuynck, Matt van de Rijn, Mushriq Al-Jazrawe, Benjamin A. Alman, Paul Coucke, Kim De Leeneer, et al.
- Targeted genome engineering in Xenopus using the transcription activator-like effector nuclease (TALEN) technology(2018)Series: Methods in Molecular Biology
Authors: Tom Van Nieuwenhuysen, Kris Vleminckx
Pages: 55 - 65 - Modeling human disease in Xenopus tropicalis using programmable nucleases(2017)
Authors: Tom Van Nieuwenhuysen
- CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis(2016)
Authors: Thomas Naert, Tom Van Nieuwenhuysen, Dionysia Dimitrakopoulou, Jannick Leoen, Jurgen Haustraete, Wouter Steyaert, Trees Lepez, Dieter Deforce, Kris Vleminckx
- TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis(2015)
Authors: Tom Van Nieuwenhuysen, Thomas Naert, Hong Tran Thi, Griet Van Imschoot, Sarah Geurs, Ellen Sanders, David Creytens, Frans Van Roy, Kris Vleminckx
Pages: 555 - 566 - TALEN mediated mutation of apc and β-catenin in Xenopus tropicalis as powerful models for Wnt driven cancer and Familial Adenomatous Polyposis (FAP)(2015)Volume: 75
Authors: Tom Van Nieuwenhuysen, Thomas Naert, David Creytens, Frans Van Roy, Kris Vleminckx
Number of pages: 1 - TLR2 activation causes no morbidity or cardiovascular failure, despite excessive systemic nitric oxide production(2013)
Authors: Benjamin Vandendriessche, Jennyfer Bultinck, Benedicte Descamps, Elke Rogge, Tom Van Nieuwenhuysen, Christian Vanhove, Peter Brouckaert
Pages: 28 - 35 - CRISPR/Cas9 mediated knockout of rcbtb1 in Xenopus tropicalis to model RCBTB1-associated retinal diseaseVolume: 59
Authors: Giulia Ascari, Thomas Naert, Tom Van Nieuwenhuysen, Suzan Demuynck, Chris Guerin, Kris Vleminckx
Number of pages: 1 - TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models
Authors: Thomas Naert, Tom Van Nieuwenhuysen, Kris Vleminckx