Researcher
Sofie Desmet
- Keywords (Ghent University):nuclear receptors
- Disciplines (Flanders Institute for Biotechnology):Analytical biochemistry, Cell death and senescence, Analysis of next-generation sequence data, General diagnostics
- Disciplines (Ghent University):Transcription and translation, Structural biology, Regulation of metabolism
Affiliations
- De Bosscher Lab (Research group)
Member
From1 Jan 2019 → 20 Feb 2022 - Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → 20 Feb 2022 - Tavernier Lab (Research group)
Member
From1 Jan 2017 → 31 Dec 2018 - Department of Biochemistry (Department)
Member
From1 Oct 2012 → 30 Sep 2018
Projects
1 - 2 of 2
- Characterization of the PPARα-ERRα interaction and crosstalk in non-alcoholic fatty liver diseaseFrom1 Oct 2019 → 20 Feb 2022Funding: BOF - postdoctoral mandates
- Study of the transcriptional cross-talk between PPARα and ERRαFrom1 Oct 2012 → 30 Sep 2016Funding: BOF - Other initiatives, FWO fellowships
Publications
1 - 10 of 12
- Nuclear receptor crosstalk : defining the mechanisms for therapeutic innovation(2020)
Authors: Sofie Desmet, Eva Estébanez-Perpiña, Luc Brunsveld
Pages: 363 - 377 - Molecular actions of PPARα in lipid metabolism and inflammation(2018)
Authors: Nadia Bougarne, Sofie Desmet, Julie Deckers, David W Ray, Bart Staels
Pages: 760 - 802 - Study of the transcriptional crosstalk between metabolic nuclear receptors(2018)
Authors: Sofie Desmet
- Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march(2018)
Authors: Julie Deckers, Nadia Bougarne, Viacheslav Mylka, Sofie Desmet, Astrid Luypaert, Michael Devos, Giel Tanghe, Justine Van Moorleghem, Manon Vanheerswynghels, Lode De Cauwer, et al.
Pages: 1360 - 1370 - Glucocorticoid receptors : finding the middle ground(2017)
Authors: Sofie Desmet
Pages: 1136 - 1145 - Compound A influences gene regulation of the dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment(2017)
Authors: Sofie Desmet, Nadia Bougarne, Lode De Cauwer, M Vuylsteke, Dariusz Ratman, R Houtman, Jan Tavernier
- Glucocorticoid receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor(2017)
Authors: Nadia Bougarne, Jolien Vandewalle, Lien Dejager, Sofie Vandevyver, Sofie Desmet, Lode De Cauwer, Samuel Lievens, Claude Libert, Jan Tavernier
- Determining the coregulator profile of the endogenous glucocorticoid receptor in lymphoid malignancies using MARCoNI(2014)
Authors: Dariusz Ratman, Sofie Desmet, René Houtman, Ilse Beck
Number of pages: 1 - The increasing complexity of glucocorticoid receptor signaling and regulation(2014)
Authors: Sofie Desmet, Ilse Beck, Nadia Bougarne, Dorien Clarisse, Julie Deckers, Dariusz Ratman, Jan Tavernier, Karolien De Bosscher
Pages: 33 - 52 - Cofactor profiling of the glucocorticoid receptor from a cellular environment(2014)Series: Methods in Molecular Biology
Authors: Sofie Desmet, Lien Dejager, Diana Melchers, Niek Bastiaensen, Rob Ruijtenbeek, Ilse Beck, Claude Libert, Renée Houtman, Onno C Meijer, Gabriella Castoria, et al.
Pages: 83 - 94