Researcher
Sofie Peirs
- Disciplines:Palliative care and end-of-life care, Laboratory medicine, Other translational sciences, Regenerative medicine, Nursing, Other clinical sciences, Other basic sciences, Other paramedical sciences, Other health sciences, Other medical and health sciences
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → 28 Feb 2019 - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2012 → 30 Sep 2018
Projects
1 - 2 of 2
- Combination therapies with the LSD1 inhibitor GSK2879552 for the treatment of T-cell acute lymphoblastic leukemiaFrom1 Oct 2016 → 31 Mar 2017Funding: Nonprofit institution or equivalents
- ETV6: the AchillesU+2019 heel of early T-cell progenitor T-cell acute lymphoblastic leukemia.From1 Oct 2012 → 30 Sep 2016Funding: FWO fellowships, BOF - Other initiatives
Publications
1 - 10 of 27
- The spleen as a sanctuary site for residual leukemic cells following ABT-199 monotherapy in ETP-ALL(2021)
Authors: Alessandra Di Grande, Sofie Peirs, Paul D. Donovan, Maaike Van Trimpont, Julie Morscio, Béatrice Lintermans, Lindy Reunes, Niels Vandamme, Steven Goossens, Hien Anh Nguyen, et al.
Pages: 1963 - 1976 - RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia(2021)
Authors: Filip Matthijssens, Nitesh D. Sharma, Monique Nysus, Christian K. Nickl, Huining Kang, Dominique R. Perez, Wouter Van Loocke, Sofie Peirs, Lindy Reunes, Filip Van Nieuwerburgh, et al.
- Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia(2019)
Authors: Gayle P Pouliot, James Degar, Laura Hinze, Bose Kochupurakkal, Chau D Vo, Melissa A Burns, Lisa Moreau, Chirag Ganesa, Justine Roderick, Sofie Peirs, et al.
- USP7 cooperates with NOTCH1 to drive the oncogenic transcriptional program in T-cell leukemia(2019)
Authors: Qi Jin, Carlos A Martinez, Kelly M Arcipowski, Yixing Zhu, Blanca T Gutierrez-Diaz, Kenneth K Wang, Megan R Johnson, Andrew G Volk, Feng Wang, Jian Wu, et al.
Pages: 222 - 239 - Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia(2019)
Authors: Gloria Milani, Filip Matthijssens, Wouter Van Loocke, Sofie Peirs, Morgan Thénoz, Lindy Reunes, Niels Vandamme, Filip Van Nieuwerburgh, Dieter Deforce, Claire Schwab, et al.
Pages: 169 - 174 - Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma(2018)
Authors: Renate De Smedt, Sofie Peirs, Julie Morscio, Filip Matthijssens, Juliette Roels, Lindy Reunes, Béatrice Lintermans, Steven Goossens, Tim Lammens, Nadine Van Roy, et al.
Pages: e17 - e20 - A novel L-asparaginase with low L-glutaminase coactivity is highly efficacious against both T- and B-cell acute lymphoblastic leukemias in vivo(2018)
Authors: Hien Anh Nguyen, Ying Su, Jenny Yu Zhang, Aleksandar Antanasijevic, Michael Caffrey, Amanda M Schalk, Li Liu, Damiano Rondelli, Annie Oh, Dolores L Mahmud, et al.
Pages: 1549 - 1560 - PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia(2018)
Authors: Ingrid M Ariës, Kimberly Bodaar, Salmaan A Karim, Triona Ni Chonghaile, Laura Hinze, Melissa A Burns, Maren Pfirrmann, James Degar, Jack T Landrigan, Sebastian Balbach, et al.
Pages: 3094 - 3114 - Novel molecular insights and targeted therapies in T-cell acute lymphoblastic leukaemia(2017)
Authors: Sofie Peirs
Pages: 244 - 246 - Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia(2017)
Authors: Sofie Peirs, Wouter Van Loocke, Jueqiong Wang, Mina Takawy, Filip Matthijssens, Stefan E Sonderegger, Katharina Haigh, Thao Nguyen, Niels Vandamme, Magdaline Costa, et al.
Pages: 981 - 990