Researcher
Lars Emil Larsen
- Keywords:Epilepsy, Seizures, Electrophysiology, Biomedical Signal Processing, Chemogenetics, Biosensors, Optogenetics, Photometry
- Disciplines:Neurological and neuromuscular diseases, Neurophysiology, Biomedical instrumentation, Biomedical signal processing, Neurosciences not elsewhere classified
Affiliations
- Department of Head and Skin (Department)
Member
From1 Oct 2019 → 15 Jul 2023 - Department of Electronics and information systems (Department)
Member
From1 Nov 2018 → 30 Sep 2023 - Department of Internal medicine (Department)
Member
From12 Oct 2012 → 24 Sep 2017
Projects
1 - 3 of 3
- Development of technology for next generation closed-loop precision therapy for seizure control in epilepsy using photopharmacology and optogeneticsFrom1 Oct 2022 → 14 Jul 2023Funding: FWO senior postdoctoral fellowship
- Soft and flexible technologies for electrical and optical modulation of the epileptic brain.From1 Jan 2022 → TodayFunding: BOF - projects
- Noradrenergic modulation of seizures and epilepsy: the good, the bad and the uglyFrom1 Nov 2021 → TodayFunding: FWO fellowships
Publications
1 - 10 of 17
- Increased dentate gyrus excitability in the intrahippocampal kainic acid mouse model for temporal lobe epilepsy(2024)
Authors: Marijke Vergaelen, Simona Manzella, Kristl Vonck, Erine Craey, Jeroen Spanoghe, Mathieu Sprengers, Evelien Carrette, Wytse Jan Wadman, Jean Delbeke, Paul Boon, et al.
- In vivo inhibition of epileptiform afterdischarges in rat hippocampus by light-activated chloride channel, stGtACR2(2023)
Authors: Anirudh Acharya, Lars Emil Larsen, Jean Delbeke, Wytse Wadman, Kristl Vonck, Alfred Meurs, Paul Boon, Robrecht Raedt
Pages: 907 - 916 - Hippocampal seizures differentially modulate locus coeruleus activity and result in consistent time-locked release of noradrenaline in rat hippocampus(2023)
Authors: Lars Emil Larsen, Sielke Caestecker, Latoya Stevens, Pieter van Mierlo, Evelien Carrette, Paul Boon, Kristl Vonck, Robrecht Raedt
- Level of hM4D(Gi) DREADD expression determines inhibitory and neurotoxic effects in the hippocampus(2021)
Authors: Marie-Gabrielle Goossens, Lars Emil Larsen, Marijke Vergaelen, Wytse Wadman, Chris Van den Haute, Wayra Brackx, Silke Proesmans, Jana Desloovere, Emma Christiaen, Erine Craey, et al.
- Optical control of excitatory transmission in hippocampal slices with photoactive adenosine A1 receptor agonist(2021)
Authors: Erine Craey, Fabian Hulpia, Serge Van Calenbergh, Lars Emil Larsen, Charlotte Mathys, Inge Van Colen, Jean Delbeke, Kristl Vonck, Paul Boon, Wytse Wadman, et al.
Number of pages: 1 - Optimized parameters for transducing the locus coeruleus using canine adenovirus type 2 (CAV2) vector in rats for chemogenetic modulation research(2021)
Authors: Latoya Stevens, Lars Emil Larsen, Wouter Van Lysebettens, Evelien Carrette, Paul Boon, Robrecht Raedt, Kristl Vonck
- Deep brain stimulation reduces evoked potentials with a dual time course in freely moving rats : potential neurophysiological basis for intermittent as an alternative to continuous stimulation(2020)
Authors: Mathieu Sprengers, Robrecht Raedt, Lars Emil Larsen, Jean Delbeke, Wytse Wadman, Paul Boon, Kristl Vonck
Pages: 903 - 913 - Dynamic functional connectivity and graph theory metrics in a rat model of temporal lobe epilepsy reveal a preference for brain states with a lower functional connectivity, segregation and integration(2020)
Authors: Emma Christiaen, Marie-Gabrielle Goossens, Benedicte Descamps, Lars Emil Larsen, Paul Boon, Robrecht Raedt, Christian Vanhove
- Spontaneous right ventricular pseudoaneurysms and increased arrhythmogenicity in a mouse model of Marfan syndrome(2020)
Authors: Felke Steijns, Marjolijn Renard, Marine Vanhomwegen, Petra Vermassen, Jana Desloovere, Robrecht Raedt, Lars Emil Larsen, Máté István Tóth, Julie De Backer, Patrick Sips
- Identification of vagus nerve stimulation parameters affecting rat hippocampal electrophysiology without temperature effects(2020)
Authors: Wouter Van Lysebettens, Kristl Vonck, Lars Emil Larsen, Latoya Stevens, Charlotte Bouckaert, Charlotte Germonpré, Mathieu Sprengers, Evelien Carrette, Jean Delbeke, Wytse Wadman, et al.
Pages: 1198 - 1206