Researcher
Sofie Martens
- Disciplines:Biophysics, Molecular and cell biology, Laboratory medicine, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From30 Aug 2013 → 31 Aug 2020
Projects
1 - 1 of 1
- Necroptotic proteins in diseases: targeting RIP kinases in inflammatory disorders and exploring the role of MLKL in melanoma developmentFrom1 Jan 2015 → 31 Dec 2018Funding: IWT personal funding - strategic basic research grants, IWT personal funding - specialisation scholarships
Publications
1 - 10 of 11
- Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state(2022)
Authors: Farzaneh Ghazavi, Jelle Huysentruyt, Stephanie Kourula, Sofie Martens, Tim Wartewig, Tatyana Divert, Ria Roelandt, Bastian Popper, Andreas Hiergeist, Peter Tougaard, et al.
- MLKL deficiency in BrafV600EPten-/- melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice(2022)
Authors: Sofie Martens, Nozomi Takahashi, Niels Vandamme, Hanne Verschuere, Tatyana Divert, Marnik Vuylsteke, Peter Vandenabeele
- MLKL in cancer : more than a necroptosis regulator(2021)
Authors: Sofie Martens, Jolien Bridelance, Ria Roelandt, Peter Vandenabeele, Nozomi Takahashi
Pages: 1757 - 1772 - Inhibitors targeting RIPK1/RIPK3 : old and new drugs(2020)
Authors: Sofie Martens, Sam Hofmans, Koen Augustyns, Peter Vandenabeele
Pages: 209 - 224 - Ionizing radiation results in a mixture of cellular outcomes including mitotic catastrophe, senescence, methuosis, and iron-dependent cell death(2020)
Authors: Sandy Adjemian Catani, Teodora-Eugenia Oltean, Sofie Martens, Bartosz Wiernicki, Tom Vanden Berghe, Benjamin Cappe, Maria Ladik, Franck Riquet, Liesbeth Heyndrickx, Jolien Bridelance, et al.
- Necroptotic proteins in diseases : targeting RIP kinases in inflammatory disorders and exploring the role of MLKL in melanoma development(2019)
Authors: Sofie Martens
- Tozasertib analogues as inhibitors of necroptotic cell death(2018)
Authors: Sam Hofmans, Lars Devisscher, Sofie Martens, Dries Van Rompaey, Kenneth Goossens, Tatyana Divert, Wim Nerinckx, Nozomi Takahashi, Hans De Winter, Pieter Van der Veken, et al.
Pages: 1895 - 1920 - RIPK1-dependent cell death : a novel target of the Aurora kinase inhibitor Tozasertib (VX-680)(2018)
Authors: Sofie Martens, Lars Devisscher, Sam Hofmans, Polien Claeys, Marnik Vuylsteke, Nozomi Takahashi, Koen Augustyns, Peter Vandenabeele
- Ionizing radiation-induced cell death(2017)
Authors: Sandy Adjemian Catani, Sofie Martens, Bartosz Wiernicki, Tania Love Aaes, Peter Vandenabeele
Number of pages: 1 - Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells(2017)
Authors: Friederike Feldmann, Barbara Schenk, Sofie Martens, Peter Vandenabeele, Simone Fulda
Pages: 68208 - 68220