Researcher
Jone Paesmans
- Keywords:Applied biological sciences, biotechnology, General and logistic services
- Disciplines:Engineering and technology
Affiliations
- R&D centraal (Administrative office)
Member
From1 Nov 2020 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Jan 2020 → 31 Oct 2020 - Department of Bio-engineering Sciences (Department)
Member
From1 Jan 2016 → 31 Dec 2019 - Faculty of Sciences and Bioengineering Sciences (Faculty)
Member
From7 Aug 2015 → 29 Jun 2021 - Department of Bio-engineering Sciences (Department)
Member
From1 Nov 2014 → 31 Oct 2020 - Faculty of Sciences and Bioengineering Sciences (Faculty)
Member
From7 Sep 2012 → 4 Jul 2014
Projects
1 - 1 of 1
- FWO-SB-Beurs: Unraveling the structure, function and molecular mechanisms of TBCID24, a new target for drug development against epilepsy and related disordersFrom1 Jan 2016 → 31 Dec 2019Funding: FWO fellowships
Publications
1 - 5 of 5
- Ontrafeling van de structuur en functie van de synaptische eiwitten TBC1D24 en Synaptojanin1 en hun rol in neurologische aandoeningen(2021)
Authors: Jone Paesmans, Wim Versées
- A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations(2020)
Authors: Jone Paesmans, Ella Martin, Babette Deckers, Marjolijn Berghmans, Ritika Sethi, Yannick Loeys, Els Pardon, Jan Steyaert, Patrik Verstreken, Christian Galicia, et al.
Pages: 1-27 - Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies(2020)
Authors: Margaux Leemans, Christian Galicia, Egon Deyaert, Elise Daems, Linda Krause, Jone Paesmans, Els Pardon, Jan Steyaert, Arjan Kortholt, Frank Sobott, et al.
Pages: 1203-1218 - TBC1D24-TLDc-related epilepsy exercise-induced dystonia(2019)
Authors: Kevin Lüthy, Davide Mei, Baptiste Fischer, Maurizio De Fusco, Jef Swerts, Jone Paesmans, Elena Parrini, Naomi Lubarr, Inge A Meijer, Katherine M Mackenzie, et al.
Pages: 2319-2335 - Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function(2016)
Authors: Baptiste Fischer, Kevin Lüthy, Jone Paesmans, Charlotte De Koninck, Ine Maes, Jef Swerts, Sabine Kuenen, Valerie Uytterhoeven, Patrik Verstreken, Wim Versées
Pages: 965-973
Patents
1 - 2 of 2
Linked dataset
1 - 3 of 3
- Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody (Creator)
- Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody. (Creator)
- Crystal structure of the TLDc domain of Skywalker/TBC1D24 from Drosophila melanogaster (Researcher)