Researcher

Luisa Vonghia

Research Expertise:Expertise in research in Non-alcoholic liver disease (NASH) and Metabolic syndrome, both pre-clinical and clinical. There is familiarity in conducting clinical trials and multiple international collaborations have been set up. Extensive phenotyping on a well-characterized population has been built up. Biomarkers analysis is a topic of interest and a collection of peripheral and hepatic venous and portal blood (which is unique) has been built up. Furthermore, there is expertise with preclinical models that are representative of both the hepatic and metabolic profile of the disease. The topics that have been developed are mainly liver-adipose tissue axis and the immunological aspects of liver and adipose tissue in NASH. In addition, there is a long expertise in clinical trials in alcoholic liver disease and also in the setting of the hepatocellular carcinoma

Research techniques:Muose models, high fat diet, high fat hjgh fructose diet, flow cytometry, gene expression. Ultrasound, elastography, fine needle biopsy.

Users of research expertise:Medical experts or researchers in the field of hepatology and metabolic diseases, patients organizations. Experts in drug development.