Drug load microbubbles for ultrasound targeted delivery in breast cancer therapy: from the model of the canine mammary gland tumors

The canine mammary gland tumor offers an interesting animal model for breast cancer in women. Contrast-enhanced ultrasonography (CEUS) may increase the efficacy of chemotherapeutics as drugs (doxorubicin liposomes) can be incorporated into the microbubble's lipid shell. With this innovative project we hope to demonstrate the diagnostic and improved therapeutic efficacy of CEUS in canine mammary gland tumors and to show the canine model's.