Researcher
Lien De Beck
- Keywords:Medicine
- Disciplines:Applied immunology, Epigenetics, Cell death, Cancer therapy
Affiliations
- Laboratory of Molecullar and Cellular Therapy (Research group)
Member
From19 Mar 2021 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Oct 2018 → 30 Sep 2023 - Basic (bio-) Medical Sciences (Department)
Member
From1 Oct 2017 → 20 Oct 2022 - Faculty of Medicine and Pharmacy (Faculty)
Member
From23 Aug 2017 → 23 Mar 2023 - Faculty of Medicine and Pharmacy (Faculty)
Member
From25 Aug 2015 → 28 Jun 2017
Projects
1 - 1 of 1
- Modulating epigenetic mechanisms to enhance cancer immunotherapy.From1 Oct 2018 → 30 Sep 2022Funding: FWO fellowships
Publications
1 - 7 of 7
- Application of epigenetic-targeting agents to confer immune modulation in cancer(2023)
Authors: Lien De Beck, Karine Breckpot, Karin Vanderkerken, Ken Maes
Number of pages: 247 - Targeted radionuclide therapy with low and high-dose Lutetium-177 labeled single domain antibodies induces distinct immune signatures in a mouse melanoma model(2022)
Authors: Thomas Ertveldt, Lien De Beck, Kirsten De Ridder, Hanne Locy, Wout De Mey, C Goyvaerts, Quentin Lecocq, Hannelore Ceuppens, Y De Vlaeminck, Robin Maximilian Awad, et al.
Pages: 1136-1148 - Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma(2022)
Authors: Lien De Beck, Robin Maximilian Awad, Veronica Basso, Noelia Casares, Kirsten De Ridder, Y De Vlaeminck, Alessandra Gnata, C Goyvaerts, Quentin Lecocq, Edurne San José-Enériz, et al.
Pages: 1-15 - TNF-alpha-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy(2022)
Authors: Kirsten De Ridder, Hanne Locy, Elisa Piccioni, Miren Ibarra Zuazo, Robin Maximilian Awad, Stefaan Verhulst, Mathias Van Bulck, Y De Vlaeminck, Quentin Lecocq, Eva Reijmen, et al.
Pages: 1-15 - Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer(2021)
Authors: Quentin Lecocq, Pieterjan Debie, Janik Puttemans, Robin Maximilian Awad, Lien De Beck, Thomas Ertveldt, Y De Vlaeminck, C Goyvaerts, Geert Raes, Marleen Keyaerts, et al.
- Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade(2021)
Authors: Robin Maximilian Awad, Quentin Lecocq, Katty Zeven, Thomas Ertveldt, Lien De Beck, Hannelore Ceuppens, Katrijn Broos, Y De Vlaeminck, C Goyvaerts, Magali Verdonck, et al.
Pages: 172-182 - Epigenetic treatment of multiple myeloma mediates tumor intrinsic and extrinsic immunomodulatory effects(2018)
Authors: Lien De Beck, Sarah Melhaoui, Kim De Veirman, Eline Menu, Elke De Bruyne, Karin Vanderkerken, Karine Breckpot, Ken Maes