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Researcher
Debby Van Dam
- Research Expertise:Animal modelling of disorders with neurological symptomatology Cognitive and behavioral alterations in Alzheimer’s disease and related neurodegenerative disorders Neurochemical and neuropathological correlates of behavioral alterations In-depth phenotyping of rodent models via assessment of various levels of learning and memory , behavioral alterations (e.g. aggression, circadian rhythm changes, anxiety), motor performance, EEG-based sleep or epilepsy studies. Rodent surgery including stereotactic procedures (non)pharmacological interventions with symptomatic or disease-modifying procedures Behavioral and biochemical biomarkers of Alzheimer’s disease in Down syndrome
- Keywords:TRANSLATIONAL NEUROSCIENCES, BEHAVIOURAL EXPERIMENTS, BRAIN AGEING, NEUROCHEMISTRY, NEURODEGENERATIVE BRAIN DISEASES, ALZHEIMER DEMENTIA, DEMENTIA, Biomedical sciences (incl. biochemistry)
- Disciplines:Behavioural neuroscience, Cognitive neuroscience, Neurological and neuromuscular diseases, Neurophysiology
- Research techniques:- Cognitive and behavioural evaluation in rodents - Pharmacological and non-pharmacological modulation of behavioural alterations - In vivo electrophysiology (sleep, epilepsy) - Neurodegenerative disorders, including Alzheimer's disease and related disorders - Animal models of neurodegenerative disorders - Surgical and stereotaxic techniques in rodents - Neurochemical and neuropathological correlaten of behavioural alterations and brain functions - Neurophysiology and behavioural neurosciences - Laboratory animal techniques including project design, legislative framework, animal welfare and ethical considerations
- Users of research expertise:Researchers requiring in-depth phenotyping and validation of rodent models including neurochemical and neuropathological correlates, pharmacological interventions and surgical procedures