Adaptation and expectation in macaque visual cortex

In this project we investigate how previous sensory input affects neural responses. A robust manifestation of the influence of recent input is neural adaptation or repetition suppression, which refers to a reduced neural activity when stimuli are repeated. Additionally neural responses could also be enhanced, for example when a stimulus is rare. These mechanisms have an important role in the predictive coding theory, which postulates that cortical responses signal violations of prior expectations. Here we investigate claims that perceptual expectations can modulate the strength of adaptation of action potential activity in macaque visual cortex.