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Project
Understanding Down syndrome as a neuro-skeletal disorder: towards integrated treatment of brain, bones and cognition
Our aim is to identify the prenatal EGCG dose that optimizes the integrated development of the brain, skull and long bones and correlates to cognitive improvement.
Date:5 Jul 2018 → 4 Jan 2021
Keywords:Down Syndrome Ts65Dn trisomic mouse model, epigallocatechin-3-gallate (EGCG), longitudinal brain and skeletal development, psychomotor and cognitive tests
Disciplines:Medical imaging and therapy, Other paramedical sciences, Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences