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Researcher
Elien Heylen
- Disciplines:Oncology, Genetics, Molecular and cell biology, Medical biotechnology, Bioinformatics and computational biology
Affiliations
- Laboratory for Disease Mechanisms in Cancer (Division)
Member
From1 Oct 2018 → Today
Projects
1 - 1 of 1
- Contribution of serine synthesis enzyme PSPH in the pathogenesis and therapeutic resistance of T-ALLFrom1 Oct 2018 → 30 Jun 2023Funding: FWO fellowships, Foundations, funds and other with scientific goal
Publications
1 - 5 of 5
- Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer(2023)
Authors: Elien Heylen, Paulien Verstraete, Linde Van Aerschot, Tom Venken, David Nittner, Anne Uyttebroeck, Heidi Segers, Diether Lambrechts, Jan Cools, Kim De Keersmaecker, et al.
Pages: 1862 - 1878 - Oncogenic drivers and therapeutic targeting of serine and glycine synthesis in cancer(2023)
Authors: Elien Heylen, Kim De Keersmaecker, Kim Kampen
- The ins and outs of serine and glycine metabolism in cancer(2021)
Authors: Elien Heylen, Kim De Keersmaecker, Kim Kampen
Pages: 131 - 141 - Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth(2021)
Authors: Shauni Geeraerts, Kim Kampen, Gianmarco Rinaldi, Purvi Gupta, Nikolaos Louros, Elien Heylen, Stijn Vereecke, Benno Verbelen, Pieter Vermeersch, Joost Schymkowitz, et al.
Pages: 50 - 63 - Carfilzomib-induced reticulocytosis in patients with multiple myeloma is caused by impaired terminal erythroid maturation(2020)
Authors: Nicolas Kint, Elien Heylen, Daniele Pepe, Kim De Keersmaecker, Catherine Verfaillie, Michel Delforge
Pages: 651 - 655