Researcher
Inge Mertens
- Research Expertise:My research focus is the identification and validation of biomarkers in liquid biopsies, with special interest in extracellular vesicles. We use mass spectrometry based proteomics.
- Keywords:EXTRACELLULAR VESICLES, DIAGNOSTICS, PROTEOMICS, Biology
- Disciplines:Protein diagnostics
- Research techniques:isolation and characterization of extracellular vesicles mass spectrometry based proteomics, clinical proteomics
- Users of research expertise:diagnostic companies, biotech companies, pharma companies external academic research groups
Affiliations
- Center for Oncological Research (CORE) (Research group)
Member
From1 Jan 2019 → Today - Molecular Imaging, Pathology, Radiotherapy & Oncology (MIPRO) (Research group)
Member
From1 Feb 2015 → 31 Dec 2018 - Biomolecular & Analytical Mass Spectrometry (BAMS) (Research group)
Member
From1 Mar 2013 → 31 Jan 2015
Projects
1 - 9 of 9
- Trapped ion mobility quadrupole time of flight mass spectrometer hyphenated to automated high throughput liquid chromatography.From30 Jun 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Center for Proteomics (CfP).From1 Jan 2022 → TodayFunding: BOF - research organisations
- Stopping the burden of disease caused by onchocerciasis-associated epilepsy.From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- IMARK. Network for image-based biomarker discovery and evaluationFrom1 Jan 2021 → TodayFunding: IOF - mandates
- Extracellular vesicles from urine as source of biomarkers for the diagnosis and follow-up of bladder cancer patients.From30 Dec 2019 → 29 Dec 2020Funding: Nonprofit institution or equivalents
- MALDI Mass Spectrometry Imaging (MALDI-MSI): Bridging proteomics and imaging.From1 May 2016 → 30 Apr 2020Funding: Own budget, for example: patrimony, inscription fees, gifts, FWO Medium Size Research Infrastructure
- CEPROMA: Centre for proteome analysis. Supporting core facilities.From1 Oct 2015 → 31 Dec 2021Funding: BOF - research organisations, Fund Recuperation Fiscal Exemption
- Molecular Imaging Mass Spectrometry platform - Nexus of Aging and Disease - an imminent global threat.From6 Jul 2015 → 31 Dec 2016Funding: Fund Recuperation Fiscal Exemption
- Urinary exosomes as biomarkers for diagnosis and follow up of bladder cancer patientsFrom2 Jul 2015 → 30 Jun 2021Funding: VITO (Flemish Institute for Technological Research)
Publications
1 - 10 of 43
- Protein biomarker discovery studies on urinary sEV fractions separated with UF-SEC for the first diagnosis and detection of recurrence in bladder cancer patients(2023)
Authors: Stephanie Jordaens, Eline Oeyen, Hanny Willems, Filip Ameye, Stefan De Wachter, Patrick Pauwels, Inge Mertens
Pages: 1 - 26 - Macrophages release extracellular vesicles of different properties and composition following exposure to nanoparticles(2023)
Authors: Sarah Deville, Hector Garcia Romeu, Eline Oeyen, Inge Mertens, Inge Nelissen, Anna Salvati
Pages: 1 - 18 - Molecular characterisation of EV-derived biomarkers in neurodegenerative conditions(2023)
Authors: Yaël Hirschberg, Inge Mertens, Kurt Boonen, Yannick Vermeiren
Number of pages: 207 - Proteomic comparison between non-purified cerebrospinal fluid and cerebrospinal fluid-derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia(2023)
Authors: Yaël Hirschberg, Natalia Valle-Tamayo, Oriol Dols-Icardo, Sebastiaan Engelborghs, Bart Buelens, Roosmarijn E. Vandenbroucke, Yannick Vermeiren, Kurt Boonen, Inge Mertens
Pages: 1 - 22 - Characterising extracellular vesicles from individual low volume cerebrospinal fluid samples, isolated by SmartSEC(2022)
Authors: Yaël Hirschberg, Kurt Boonen, Karin Schildermans, Annemieke van Dam, Isabel Pintelon, Charysse Vandendriessche, Milica Velimirovic, An Jacobs, Roosmarijn E. Vandenbroucke, Inge Nelissen, et al.
Pages: 1 - 18 - Four layer multi-omics reveals molecular responses to aneuploidy in Leishmania(2022)
Authors: Bart Cuypers, Pieter Meysman, Ionas Erb, Wout Bittremieux, Dirk Valkenborg, Geert Baggerman, Inge Mertens, Shyam Sundar, Basudha Khanal, Cedric Notredame, et al.
Pages: 1 - 23 - Urinary extracellular vesicles as source of biomarkers for the diagnosis and follow up of bladder cancer patients(2021)
Authors: Eline Oeyen, Geert Baggerman, Inge Mertens
Number of pages: 202 - Urinary extracellular vesicles(2021)
Authors: Uta Erdbrugger, Charles J. Blijdorp, Irene V. Bijnsdorp, Francesc E. Borras, Dylan Burger, Benedetta Bussolati, James Brian Byrd, Aled Clayton, James W. Dear, Juan M. Falcon-Perez, et al.
- Implementation of MALDI mass spectrometry imaging in cancer proteomics research(2020)
Authors: Eline Berghmans, Kurt Boonen, Evelyne Maes, Inge Mertens, Patrick Pauwels, Geert Baggerman
Pages: 1 - 12 - Biofluid markers for prodromal Parkinson's disease(2020)
Authors: Yannick Vermeiren, Yael Hirschberg, Inge Mertens
Pages: 1 - 9
Patents
1 - 1 of 1
- Biomarkers for typing allograft recipients (Inventor)