Researcher
Sigrid Verhelst
- Keywords:LC-MS, Epigenetics, Histones, bottom-up proteomics, post-translational modifications
- Disciplines:Toxicogenomics, Epigenetics, Proteins, Proteomics, Posttranslational modifications, Pharmaceutical care, Compound screening, In vitro testing
Affiliations
- Department of Pharmaceutics (Department)
Member
From30 Aug 2019 → Today
Projects
1 - 2 of 2
- Cofunding core facility - ProGenTomicsFrom1 Dec 2023 → TodayFunding: BOF - research organisations
- High throughput MS-based histone PTM screening: Filling a void in pharmacoepigenetics.From1 Nov 2019 → 23 Dec 2023Funding: FWO Strategic Basic Research Grant
Publications
1 - 8 of 8
- A large scale mass spectrometry-based histone screening for assessing epigenetic developmental toxicity(2022)
Authors: Sigrid Verhelst, Bart Van Puyvelde, Sander Willems, Simon Daled, Senne Cornelis, Laura Corveleyn, Ewoud Willems, Dieter Deforce, Laura De Clerck, Maarten Dhaenens
- An interactive mass spectrometry atlas of histone posttranslational modifications in T-cell acute leukemia(2022)
Authors: Lien Provez, Bart Van Puyvelde, Laura Corveleyn, Nina Demeulemeester, Sigrid Verhelst, Beatrice Lintermans, Simon Daled, Juliette Roels, Lieven Clement, Lennart Martens, et al.
- Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction(2022)
Authors: Dick W. Zijlmans, Irene Talon, Sigrid Verhelst, Adam Bendall, Karlien Van Nerum, Alok Javali, Andrew A. Malcolm, Sam S. F. A. van Knippenberg, Laura Biggins, San Kit To, et al.
Pages: 858 - 871 - Cov-MS : a community-based template assay for mass-spectrometry-based protein detection in SARS-CoV-2 patients(2021)
Authors: Bart Van Puyvelde, Katleen Van Uytfanghe, Olivier Tytgat, Laurence Van Oudenhove, Robbin Bouwmeester, Simon Daled, Sigrid Verhelst, Laura De Clerck, Laura Corveleyn, Sander Willems, et al.
Pages: 750 - 765 - Histone sample preparation for bottom-up mass spectrometry : a roadmap to informed decisions(2021)
Authors: Simon Daled, Sander Willems, Bart Van Puyvelde, Laura Corveleyn, Sigrid Verhelst, Laura De Clerck, Dieter Deforce, Maarten Dhaenens
- An experimental design to extract more information from MS-based histone studies(2021)
Authors: Laura De Clerck, Sander Willems, Simon Daled, Bart Van Puyvelde, Sigrid Verhelst, Laura Corveleyn, Dieter Deforce, Maarten Dhaenens
Pages: 929 - 938 - Comprehensive histone epigenetics : a mass spectrometry based screening assay to measure epigenetic toxicity(2020)
Authors: Sigrid Verhelst, Laura De Clerck, Sander Willems, Bart Van Puyvelde, Simon Daled, Dieter Deforce, Maarten Dhaenens
- The perspectives of parents, general practitioners, and community pharmacists about treating an ill child in primary care : a comparative study(2019)
Authors: Sigrid Verhelst, Pauline De Bruyne, Myriam Van Winckel, Koen Boussery, Eline Tommelein
Pages: 111 - 119