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Project
PDE4D: a novel target in the treatment of progressive multiple sclerosis (R-10210)
In a first phase, we aim to identify therapeutically relevant PDE4D isoforms to pave the way towards novel compound development, setup innovative screening assays in-house, and advance the proof-of-concept of PDE4D inhibition to target pMS. Phase 2 will move into an industrial setting where we will also setup challenging screening assays and further investigate the therapeutic potential for the compounds that were elected based on phase 1.
Date:1 Oct 2019 → 31 Dec 2020
Keywords:MULTIPLE SCLEROSIS, phosphodiesterase
Disciplines:Cognitive neuroscience