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Project

The Flemish exposome project: towards a comprehensive understanding of the life-course impact of dietary and environmental exposure on chronic low-grade gut inflammation Acronym = FLEXiGUT (R-11423)

The human exposome covers the totality of non-genetic exposures from conception throughout the life course. The Flemish exposome project, FLEXiGUT, combines the unique and complementary expertise in Flanders on dietary- and environment-related human biomarkers and biomonitoring, metabolomics, microbiome research and epidemiology to investigate the complex human exposome. This first large-scale Flemish Exposome study, will make use of biomonitoring and -omics based technologies on the available biological matrices of the Flemish Environage Birth and the Flemish Gut Microbiome cohorts. Associations between the acquired exposome metadata and chronic low-grade gut inflammation parameters and related diseases will be analysed using an integrated -omics approach. Our pioneering results will be validated through extension towards other international cohorts.
Date:1 Jan 2021 →  Today
Keywords:chronic exposure, Exposome, human biomonitoring, metabolomics, microbiome
Disciplines:Other environmental sciences not elsewhere classified, Environmental health and safety, Epidemiology, Medical metabolomics, Microbiome
Project type:Collaboration project