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Project

STOP SEPSIS

With 30 million cases, 8 million deaths (3 million children) yearly, sepsis (strongly underfunded) is a huge medical problem. We suggest the innovative principle that sepsis is a failing starvation response which is based on failing key molecules (identified by us) in the liver. The mechanism of their failure, the consequences and therapeutics following form the basis of this project.

Date:1 Jan 2021 →  Today
Keywords:multidisciplinary, Metabolism, infection, medical need, inflammation
Disciplines:Regulation of metabolism, Genome structure and regulation, Infectious diseases, Metabolomics, Energy metabolism