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Project

lnvestigating precision in predictive coding during walking to music in multiple sclerosis; with progressive subtypes and cerebellar lesions. (R-11658)

Walking, is essential for daily activity, yet challenging to train in persons with multiple sclerosis (PwMS) with progressive subtypes and with PwMS with cerebellar lesions, given the prevalence of symptoms of fatigability and ataxia in the diseases respectively. Walking requires not only motor, but also cognitive functions, such as attention. This poses an additional challenge to train walking in PwMS with progressive subtypes and PwMS with cerebellar lesions, where cognitive impairment is prevalent. In this project, we propose the use of walking tasks involving auditory-motor coupling- that is synchronised walking to music - embedded in the theoretical framework of predictive coding. The overall aim of the project is to understand how impairments in motor, cognitive and perceptual timing systems (and particularly fatigability and cerebellar lesions) effects precision in PwMS compared to healthy controls.
Date:1 Oct 2020 →  31 Dec 2022
Keywords:Multiple Sclerosis, Music, Synchronisation
Disciplines:Rehabilitation, Rehabilitation sciences not elsewhere classified