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Project

Post Treatment dosimetry system for patient specific Quality assurance

The current project intends to develop a surface dosimetry system for radiotherapy. The general research objective includes the selection of optimal Radiophotoluminiscent material (RPL) and an optimal read-out strategy. The final goal is to investigate the feasibility of a RPL coating on immobilization masks as are typically utilized in certain treatment types and that would allow for quality assurance of the treatment after each treatment fraction and/or to verify the accumulated dose over all fractions. First the dosimetric properties of RPL are investigated. The dose response is analyzed on a microscopic level utilizing Monte Carlo simulations. The simulations will be benchmarked with measurement on mono-energetic sources at Laboratory for Nuclear Calibrations (LNK) in SCK CEN. LNK performs dosimetry calibrations and irradiations with γ-rays, X-rays and neutrons for almost any type of dosimeter and sample used in research institutions. Second the performance of a 3D reader will be analyzed in terms of image quality, spatial resolution, sensitivity etc. Finally, surface doses deposited by clinical LINACS measured on the masks can will be compared with doses planned using the TPS (treatment planning system).This RPL research will be executed in the context of a larger VLAIO project that investigates the whole bench-to-bedside trajectory from lab to clinical plans for three luminescence-based dosimetry systems: pre-treatment dosimetry, in-vivo dosimetry, and post-treatment dosimetry. The project will be executed by a collaboration with the Belgian Nuclear Research Centre (SCK CEN) and the Innovation Office of AGFA.
Date:25 May 2021 →  14 Aug 2021
Keywords:Radiophotoluminiscence, Quality Assurance, Dosimetry, Monte Carlo, Dose Mask, 3D reader, Treatment Planning System
Disciplines:Medical biophysics, Radiation therapy, Image-guided interventions, Medical biotechnology not elsewhere classified
Project type:PhD project