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Project

Depressed Skull fractures: Timing of surgery, systemic inflammatory response, surgical site infection, and post-traumatic seizures - (DESTINE Study)

The timing for surgery of depressed skull fracture (DSF) in low-income-countries remains unclear due to the risks from the intraoperative bleeding versus surgical site infection. Neuro-inflammation induced by trauma, anaesthesia, and surgery stress predispose patients to late post-traumatic epilepsy. Indepth immunological, imaging, and clinical studies of patients with DSF could improve the understanding and decision-making of the surgical timing.

Date:1 Oct 2021 →  Today
Keywords:surgical site infection, post-traumatic epilepsy, timing of surgery, Depressed skull fracture, systemic inflammatory responses
Disciplines:Neurosurgery