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Relaxation oscillations and canards of a regulated two-gene model

Journal Contribution - Journal Article

We investigate a two-gene system with an autoregulatory feedback loop using geometric singular perturbation theory. We identify (coexisting) relaxation oscillations, singular Hopf bifurcations, homoclinic loops etc. We also demonstrate a new method to compute the criticality of the singular Hopf bifurcations. (c) 2021 Elsevier Inc. All rights reserved.
Journal: JOURNAL OF MATHEMATICAL ANALYSIS AND APPLICATIONS
ISSN: 0022-247X
Issue: 1
Volume: 502
Publication year:2021
Keywords:Gene expression, Regulatory network, Canards, Relaxation oscillations, Singular Hopf bifurcation, Geometric singular perturbation theory
BOF-keylabel:yes
IOF-keylabel:yes
BOF-publication weight:2
Authors:International
Authors from:Higher Education
Accessibility:Open