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Project

Pre-programmed iPS-derived cartilaginous tissues as a base for engineering next-generation skeletal implants

Articular cartilage damage/defect in the knee joint is a relatively common clinical problem since it has only limited capacity for self-repairing. Induced pluripotent stem cells (iPSCs) has been widely investigated in the field of skeletal regenerative therapies due to their pluripotency and unlimited self-renewal capacity. Moreover, iPSCs are regarded as alternative cell sources in regenerative medicine and the stable cartilage phenotypic has been demonstrated in both rat and mini-pig cartilage defect models. So it would be prospective to explore pre-programmed iPS-derived cartilaginous tissues as skeletal implants.

Date:1 Nov 2021 →  Today
Keywords:Induced pluripotent stem cells
Disciplines:Tissue engineering
Project type:PhD project