Researcher
Donovan Flumens
- Keywords:Medicine
- Disciplines:Cellular therapy, Gene and molecular therapy, Hematology
Affiliations
- Laboratory for Experimental Hematology (LEH) (Research group)
Member
From1 Nov 2021 → Today
Projects
1 - 2 of 2
- MulTplex project: Innovating on combinatorial genetically engineered adoptive Tcell therapies against hematological diseases.From1 Nov 2021 → 31 Oct 2022Funding: Nonprofit institution or equivalents
- MulTplex project: Development of a combinatorial multi-epitope T-cell receptor (TCR), non-signaling chimeric antigen receptor (NSCAR) and immunosuppressive immune checkpoint (IICP)-disrupted adoptive T-cell therapy against leukemia.From1 Oct 2021 → TodayFunding: BOF - doctoral mandates
Publications
1 - 8 of 8
- Training of epitope-TCR prediction models with healthy donor-derived cancer-specific T cells(2023)
Authors: Donovan Flumens, Sofie Gielis, Esther Bartholomeus, Diana Campillo Davó, Maarten Versteven, Hans De Reu, Evelien Smits, Benson Ogunjimi, Kris Laukens, Pieter Meysman, et al.
Pages: 1 - 18 - In vitro expansion of Wilms’ tumor protein 1 epitope-specific primary T cells from healthy human peripheral blood mononuclear cells(2023)
Authors: Donovan Flumens, Maarten Versteven, Hans De Reu, Diana Campillo Davó, Yannick Willemen, Benson Ogunjimi, Vigor Van Tendeloo, Zwi Berneman, Sébastien Anguille, Evelien Smits, et al.
Pages: 1 - 18 - Analysis of Wilms’ tumor protein 1 specific TCR repertoire in AML patients uncovers higher diversity in patients in remission than in relapsed(2023)
Authors: Sofie Gielis, Donovan Flumens, Maarten Versteven, Hans De Reu, Esther Bartholomeus, Jolien Schippers, Diana Campillo Davó, Zwi Berneman, Sébastien Anguille, Evelien Smits, et al.
Number of pages: 24 - One-step CRISPR-Cas9-mediated knockout of native TCRαβ genes in human T cells using RNA electroporation(2023)
Authors: Donovan Flumens, Diana Campillo Davó, Ibo Janssens, Gils Roex, Jorrit De Waele, Sébastien Anguille, Eva Lion
Pages: 1 - 21 - Two for one(2022)
Authors: Gils Roex, Diana Campillo Davó, Donovan Flumens, Philip Shaw, Hans De Reu, Eva Lion, Sébastien Anguille
Pages: 1 - 13 - Anti-tumor potency of short-term interleukin-15 dendritic cells is potentiated by in situ silencing of programmed-death ligands(2022)
Authors: Maarten Versteven, Donovan Flumens, Diana Campillo Davó, Hans De Reu, Laura Van Bruggen, Vigor Van Tendeloo, Zwi Berneman, Harry Dolstra, Sébastien Anguille, Willemijn Hobo, et al.
- The ins and outs of messenger RNA electroporation for physical gene delivery in immune cell-based therapy(2021)
Authors: Diana Campillo Davó, Maxime De Laere, Gils Roex, Maarten Versteven, Donovan Flumens, Zwi Berneman, Vigor Van Tendeloo, Sébastien Anguille, Eva Lion
- Safety and clinical efficacy of BCMA CAR-T-cell therapy in multiple myeloma(2020)
Authors: Gils Roex, Marijke Timmers, Diana Campillo Davó, Donovan Flumens, Wilfried Schroyens, Yiwei Chu, Zwi Berneman, Eva Lion, Feifei Luo, Sébastien Anguille