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Project
Mechanistic study on the prediction of the pharmacokinetics of drugs in children
This project aims to evaluate the usefulness of Physiologically Based Pharmacokinetic (PBKP) - Modelling in predicting the pharmacokinetics of drugs en paediatric populations. Current knowledge on PBPK-modelling in children will be expanded, an the resulting model will be tested and validated using the model drugs tramadol and propofol.
Date:1 Jan 2012 → 31 Dec 2016
Keywords:PBPK-modelling, pharmacokinetics, paediatric drug development
Disciplines:Other pharmaceutical sciences, Pharmaceutics, Toxicology and toxinology, Pharmacotherapy, Pharmacognosy and phytochemistry, Biomarker discovery and evaluation, Medicinal products, Drug discovery and development, Pharmacology