Network-based approaches for the identification and mode of action determination of anti-bacterial agents

Drug repurposing and the design of polypharmacological and drug-cocktailing strategies by combining in-house phenotypic and molecular data with advanced bioinformatics approaches. This implies 1) constructing drug-target networks,

2) constructing interaction networks from publicly available data, 3) determining the mode of action of drugs by interrogating interaction networks with in-house data, 4) testing the phenotypic and molecular effect of anti-biofilm agents.