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Project
DNA complexation using amphiphilic cationic molecules
By organic synthesis aphiphilic molecules are prepared with the ability to form hydrophobic multimolecular complexes with DNA. Their efficiency with respect to itact transport of DNA into the cellular nucleus will be evaluated using biophysical techniques such as FRAP, DLS, FCS and Single Particle Tracking.
Date:1 Dec 2007 → 31 Mar 2009
Keywords:nuclear transport, gene therapy, dna
Disciplines:Process engineering, Polymeric materials, Biochemistry and metabolism, Medical biochemistry and metabolism