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Project

Sorting out functionally conserved plant orthologs using comparative expression analysis

New methods will be developed to predict functions for genes and transcripts. These methods will robustly transfer functions between coexpressing transcripts and will detect orthologs with a conserved coexpression context. This allows to make high quality function predictions, even for species with few known exerimental functions or with a large evolutionary distance to a model organism.

Date:1 Jan 2015 →  31 Dec 2020
Keywords:alternative splicing, gene ontology, comparative transcriptomics, orthology, RNA-Seq, function prediction
Disciplines:Scientific computing, Bioinformatics and computational biology, Other (bio)medical engineering, Industrial biotechnology, Biomaterials engineering, Other biotechnology, bio-engineering and biosystem engineering, Public health services, Biomechanical engineering, Public health care, Plant biology, Environmental engineering and biotechnology, Biological system engineering